In recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing sys-tems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymers due to their biocompatibility, biodegradability, low immunogenicity, and adaptability. Among these proteins, keratin, extracted from waste wool, and fibroin, derived from Bombyx mori cocoons, exhibit exceptional properties such as mechanical strength, cell adhe-sion capabilities, and suitability for various fabrication methods. These proteins can also be func-tionalized with antimicrobial, antioxidant, and anti-inflammatory compounds, making them highly versatile for biomedical applications. This review highlights the promising potential of keratin- and fibroin-based films as innovative platforms for wound healing, emphasizing their advantages and the prospects they offer in creating next-generation wound dressing devices.

Natural Protein Films from Textile Wastes for Wound Healing and Wound Dressing Applications

Livia Ottaviano;Sara Buoso;Roberto Zamboni;Giovanna Sotgiu
;
Tamara Posati
2024

Abstract

In recent years, several studies have focused on the development of sustainable, biocompatible, and biodegradable films with potential applications in wound healing and wound dressing sys-tems. Natural macromolecules, particularly proteins, have emerged as attractive alternatives to synthetic polymers due to their biocompatibility, biodegradability, low immunogenicity, and adaptability. Among these proteins, keratin, extracted from waste wool, and fibroin, derived from Bombyx mori cocoons, exhibit exceptional properties such as mechanical strength, cell adhe-sion capabilities, and suitability for various fabrication methods. These proteins can also be func-tionalized with antimicrobial, antioxidant, and anti-inflammatory compounds, making them highly versatile for biomedical applications. This review highlights the promising potential of keratin- and fibroin-based films as innovative platforms for wound healing, emphasizing their advantages and the prospects they offer in creating next-generation wound dressing devices.
2024
Istituto per la Sintesi Organica e la Fotoreattivita' - ISOF
Silk Fibroin films
Keratin films
Wound healing
Wound dressing
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Descrizione: Natural protein films from textile wastes for wound healing and wound dressing applications
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/523563
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