Carbocatalysis expands its applicability to the synthesis of indenes via intramolecular Friedel-Crafts like alkylation of Morita-Baylis-Hilman alcohols. Graphene oxide (GO) dictated the conditions to document a C−C bond forming protocol featuring large scope (14 examples) and moderate to high yield (45-80 %) under mild reaction conditions. Detailed mechanistic investigation completed the present study.
Synthesis of Indenes via Graphene Oxide Mediated Manipulation of Morita‐Baylis‐Hillman Alcohols
Mantovani, Sebastiano;Pintus, Angela;Kovtun, Alessandro;Melucci, Manuela;
2023
Abstract
Carbocatalysis expands its applicability to the synthesis of indenes via intramolecular Friedel-Crafts like alkylation of Morita-Baylis-Hilman alcohols. Graphene oxide (GO) dictated the conditions to document a C−C bond forming protocol featuring large scope (14 examples) and moderate to high yield (45-80 %) under mild reaction conditions. Detailed mechanistic investigation completed the present study.File in questo prodotto:
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59_Mantovani_Morita_Eur J Org Chem - 2023.pdf
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