Our recent publication “Transcriptomic Profiles of Monocyte-Derived Macrophages Exposed to SARS-CoV-2 VOCs Reveal Immune-Evasion Escape Driven by Delta” revealed a transcriptomic alteration and an evolution of the host monocyte-derived macrophages (MDM) in response to the exposure to SARS-CoV-2 VOCs, particularly for Delta variant. We now decided to investigate the effects of inactivated SARS-CoV-2 VOCs exposure on human MDMs, with a particular focus on the immune response key players.
Exposure of monocyte-derived macrophages to the UV-inactivated SARS-CoV-2 VOCs shows similar effects on the transcriptomic profile as active virus: a comparative analysis
Giambruno, Roberto;
2025
Abstract
Our recent publication “Transcriptomic Profiles of Monocyte-Derived Macrophages Exposed to SARS-CoV-2 VOCs Reveal Immune-Evasion Escape Driven by Delta” revealed a transcriptomic alteration and an evolution of the host monocyte-derived macrophages (MDM) in response to the exposure to SARS-CoV-2 VOCs, particularly for Delta variant. We now decided to investigate the effects of inactivated SARS-CoV-2 VOCs exposure on human MDMs, with a particular focus on the immune response key players.File in questo prodotto:
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