Synthesis of a Zn(II) coordination polymer for luminescent detection of biomolecules: A case study with ATP

A new Zn(II)-based luminescent coordination polymer (CP), [Zn(BPYP)(NPA)·DMF·3H₂O]ₙ (1) (BPYP = 2,5-bis(pyrid-4-yl)pyridine; H₂NPA = 4-nitroisophthalic acid), was synthesized via a mixed-ligand hydrothermal method. Single-crystal X-ray diffraction revealed a 2D layered framework with 1D channels and Zn(II) centers in a distorted tetrahedral geometry. CP (1) demonstrates high selectivity and sensitivity for adenosine triphosphate (ATP) detection through significant fluorescence quenching, driven by the inner filter effect and photoinduced electron transfer. The sensor performs reliably in various real water samples, with recoveries of 93.88–101.86 % and RSDs below 2.8 %. Showing low detection limit (LOD) 5.77 × 10−5 ML−1 and Stern–Volmer quenching constant (Ksv) of 0.993 × 103 M−1. Its robust stability and recyclability highlight CP (1) as a promising and reusable fluorescent platform for environmental and biological ATP sensing.