Electro Fluid Dynamic Technologies to Engineer 3D Matrices for Glial Cells in Brain

The intricate web of the mind relies heavily on connections between neurons and glial cells, particularly astrocytes, oligodendrocytes, and microglia. While neurological research has traditionally focused on neurons, the crucial roles of glial cells in maintaining homeostasis, supporting synaptic functions, and structuring brain development have become more obvious. Advanced models that can properly reproduce the brain’s microenvironment are necessary to understand how it works and what causes its malfunction. Electro fluid dynamic technologies like electrospraying and electrospinning techniques, present new ways of creating complicated three-dimensional scaffolds suitable for glial cell growth and function. This study discusses how these technologies can be applied to create scaffolds that mimic natural extracellular matrices, improving interactions among glial cells that facilitate insights into brain homeostasis and neural communication.