In this paper, we propose a numerical study of macroscopic models for collective cell migration, focusing on a multidimensional pressureless Euler-type model with nonlocal interactions coupled with chemotaxis, rigorously derived from microscopic dynamics. Different mechanical interactions are investigated, including attraction-repulsion effects. Moreover, the model is extended to the case of different populations of interacting cells. The validity of such a macroscopic model and its agreement with the microscopic dynamics is finally assessed through a parameter estimation analysis in a specific setting.

NUMERICAL STUDY ON A MULTIDIMENSIONAL PRESSURELESS EULER-TYPE MODEL WITH NONLOCAL INTERACTIONS AND CHEMOTAXIS FOR COLLECTIVE CELL MIGRATION

Menci M.;Natalini R.;
2026

Abstract

In this paper, we propose a numerical study of macroscopic models for collective cell migration, focusing on a multidimensional pressureless Euler-type model with nonlocal interactions coupled with chemotaxis, rigorously derived from microscopic dynamics. Different mechanical interactions are investigated, including attraction-repulsion effects. Moreover, the model is extended to the case of different populations of interacting cells. The validity of such a macroscopic model and its agreement with the microscopic dynamics is finally assessed through a parameter estimation analysis in a specific setting.
2026
Istituto Applicazioni del Calcolo ''Mauro Picone''
PDE, chemotaxis models, nonlocal models, inverse problems, parameter estimation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/583562
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