We have reconstituted rat liver gap junction in single phospholipids membrane, forming a single-membrane functional channel. Our objectives were (a) to evaluate the effect of ELF-EMFs on the permeability and gating of the single-membrane connexin channels, and (b) to relate the nature of any observable effect to our previous proposed theoretical model.

Effect of low-frequency electromagnetic fields on gap junction connexin-32 channels reconstituted in liposomes.

Ramundo Orlando Alfonsina;
2001

Abstract

We have reconstituted rat liver gap junction in single phospholipids membrane, forming a single-membrane functional channel. Our objectives were (a) to evaluate the effect of ELF-EMFs on the permeability and gating of the single-membrane connexin channels, and (b) to relate the nature of any observable effect to our previous proposed theoretical model.
2001
NEUROBIOLOGIA E MEDICINA MOLECOLARE
gap junction; liposomes; mechanism of cation; electromagnetic fields
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/58898
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