Esophageal adenocarcinoma and its precursor, Barrett’s esophagus (BE), are associated with a pro-inflammatory, Gram-negative-dominated esophageal microbiome. In a single-arm pilot study, 23 patients with BE consumed a fermented milk drink containing Lactobacillus casei strain Shirota (LcS) twice daily for 4 weeks, based on the hypothesis that this intervention could shift the microbiome toward a more beneficial Gram-positive profile.
A fermented milk drink containing Lactobacillus casei strain Shirota modulates the esophageal microbiome composition in Barrett’s esophagus
Maria Laura Ferrando;
2026
Abstract
Esophageal adenocarcinoma and its precursor, Barrett’s esophagus (BE), are associated with a pro-inflammatory, Gram-negative-dominated esophageal microbiome. In a single-arm pilot study, 23 patients with BE consumed a fermented milk drink containing Lactobacillus casei strain Shirota (LcS) twice daily for 4 weeks, based on the hypothesis that this intervention could shift the microbiome toward a more beneficial Gram-positive profile.File in questo prodotto:
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