Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.
Click chemistry to functionalise peptidomimetics
D Arosio;L Manzoni;
2006
Abstract
Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.File in questo prodotto:
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Descrizione: Click chemistry to functionalise peptidomimetics
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