OBJECTIVES: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD- subjects. DESIGN AND METHODS: Identification of heterozygous G6PD- subjects was done by the measurement of G6PD activity and by a cytochemical test. RESULTS: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD- subjects. CONCLUSIONS: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD- heterozygotes.

Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency

Antonio Tagarelli;Anna Piro;Loredana Bastone;Giuseppe Tagarelli
2006

Abstract

OBJECTIVES: To determine if the qualitative test (cytochemical) is more reliable than the quantitative test (differential pH-metry) in identifying heterozygous G6PD- subjects. DESIGN AND METHODS: Identification of heterozygous G6PD- subjects was done by the measurement of G6PD activity and by a cytochemical test. RESULTS: A cytochemical test is more sensitive than differential pH-metry to identify heterozygous G6PD- subjects. CONCLUSIONS: A cytochemical test is a reliable method for mass screening for G6PD deficiency to identify G6PD- heterozygotes.
2006
Istituto di Scienze Neurologiche - ISN - Sede Mangone
G6PD deficiency; Differential pH-metry; Cytochemical test; Calabria population; Southern Italy
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Descrizione: Reliability of quantitative and qualitative tests to identify heterozygotes carrying severe or mild G6PD deficiency
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/76662
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