Neisseria meningitidis is an encapsulated Gram-negative bacterium responsible for significant morbidity and mortality worldwide. Meningococci are opportunistic pathogens, carried in the nasopharynx of approximately 10% of asymptomatic adults. Here we describe a two-dimensional gel electrophoresis protein map of the serogroup A strain Z4970, a clinical isolate classified as ancestral to several pandemic waves. Since menA differs from other serogroups by having a fairly stable clonal population structure (i.e. with a low degree of variability), we envisaged comparative mapping as a useful tool for microevolution studies.
COMPARATIVE PROTEOMICS AS A TOOL TO IDENTIFY NOVEL MARKERS OF MENINGOCOCCUS A EPIDEMIOLOGY.
Renzone G;Scaloni A;
2005
Abstract
Neisseria meningitidis is an encapsulated Gram-negative bacterium responsible for significant morbidity and mortality worldwide. Meningococci are opportunistic pathogens, carried in the nasopharynx of approximately 10% of asymptomatic adults. Here we describe a two-dimensional gel electrophoresis protein map of the serogroup A strain Z4970, a clinical isolate classified as ancestral to several pandemic waves. Since menA differs from other serogroups by having a fairly stable clonal population structure (i.e. with a low degree of variability), we envisaged comparative mapping as a useful tool for microevolution studies.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
8th National Biotechnology Congress_2005_Bernardini et al.pdf
non disponibili
Tipologia:
Abstract
Licenza:
Nessuna licenza dichiarata (non attribuibile a prodotti successivi al 2023)
Dimensione
136.84 kB
Formato
Adobe PDF
|
136.84 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
