GARBELLI, ANNA
GARBELLI, ANNA
Istituto di Genetica Molecolare "Luigi Luca Cavalli Sforza"
DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective
2022 Garbelli, A; Bione, S; Maga, G
A Role for Human DNA Polymerase lambda in Alternative Lengthening of Telomeres
2021 Mentegari, E; Bertoletti, F; Kissova, M; Zucca, E; Galli, S; Tagliavini, G; Garbelli, A; Maffia, A; Bione, S; Ferrari, E; d'Adda di Fagagna, F; Francia, S; Sabbioneda, S; Chen, Ly; Lingner, J; Bergoglio, V; Hoffmann, Js; Hubscher, U; Crespan, E; Maga, G
Targeting ddx3x helicase activity with ba103 shows promising therapeutic effects in preclinical glioblastoma models
2021 Brai A; Riva V; Clementi L; Falsitta L; Zamperini C; Sinigiani V; Festuccia C; Sabetta S; Aiello D; Roselli C; Garbelli A; Trivisani CI; Maccari L; Bugli F; Sanguinetti M; Calandro P; Chiariello M; Quaranta P; Botta L; Angelucci A; Maga G; Botta M.
DDX3X Inhibitors, an Effective Way to Overcome HIV-1 Resistance Targeting Host Proteins
2020 Brai A; Riva V; Saladini F; Zamperini C; Trivisani CI; Garbelli A; Pennisi C; Giannini A; Boccuto A; Bugli F; Martini M; Sanguinetti M; Zazzi M; Dreassi E; Botta M; Maga G.
Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor
2020 Brai, A; Boccuto, A; Monti, M; Marchi, S; Vicenti, I; Saladini, F; Trivisani, Ci; Pollutri, A; Trombetta, Cm; Montomoli, E; Riva, V; Garbelli, A; Nola, Em; Zazzi, M; Maga, G; Dreassi, E; Botta, M
Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases
2020 Riva V; Garbelli A; Casiraghi F; Arena F; Trivisani CI; Gagliardi A; Bini L; Schroeder M; Maffia A; Sabbioneda S; Maga G.
Novel Insights into the Biochemical Mechanism of CK1epsilon and its Functional Interplay with DDX3X
2020 Bono, B; Franco, G; Riva, V; Garbelli, A; Maga, G
Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses
2020 Riva V; Garbelli A; Brai A; Casiraghi F; Fazi R; Trivisani CI; Boccuto A; Saladini F; Vicenti I; Martelli F; Zazzi M; Giannecchini S; Dreassi E; Botta M; Maga G.
DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection
2019 Brai, A; Martelli, F; Riva, V; Garbelli, A; Fazi, R; Zamperini, C; Pollutri, A; Falsitta, L; Ronzini, S; Maccari, L; Maga, G; Giannecchini, S; Botta, M
Synthesis and antiviral activity of novel 1,3,4-thiadiazole inhibitors of DDX3x
2019 Brai A; Ronzini S; Riva V; Botta L; Zamperini C; Borgini M; Trivisani CI; Garbelli A; Pennisi C; Boccuto A; Saladini F; Zazzi M; Maga G; Botta M.
How to win the HIV-1 drug resistance hurdle race: Running faster or jumping higher?
2017 Garbelli, A; Riva, V; Crespan, E; Maga, G
The power of enzyme kinetics in the drug development process
2013 Samuele, A; Crespan, E; Garbelli, A; Bavagnoli, L; Maga, G
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors
2012 Radi, M; Falchi, F; Garbelli, A; Samuele, A; Bernardo, V; Paolucci, S; Baldanti, F; Schenone, S; Manetti, F; Maga, G; Botta, M
A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication.
2011 Garbelli A; Beermann S; Di Cicco G; Dietrich U; Maga G.
Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents.
2011 Crespan, E; Garbelli, A; Amoroso, A; Maga, G
Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication.
2011 Garbelli A; Radi M; Falchi F; Beermann S; Zanoli S; Manetti F; Dietrich U; Botta M; Maga G.
The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection.
2011 Bavagnoli, L; Dundon, Wg; Garbelli, A; Zecchin, B; Milani, A; Parakkal, G; Baldanti, F; Paolucci, S; Volmer, R; Tu, Y; Wu, C; Capua, I; Maga, G
Inhibitors of human immunodeficiency virus-1 replication targeting the human dead-box polypeptide 3 (DDX3) RNA helicase
2010 Maga G; Falchi F; Garbelli A; Radi M; Paolucci S; Baldanti F; Botta M
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3.
2008 Maga, G; Falchi, F; Garbelli, A; Belfiore, A; Witvrouw, M; Manetti, F; Botta, M
Expression, characterization of human DDX3 protein and construction of mutants.
2007 Garbelli, A; Franca, R; Belfiore, A; Maga, G
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective | 1-gen-2022 | Garbelli, A; Bione, S; Maga, G | |
| A Role for Human DNA Polymerase lambda in Alternative Lengthening of Telomeres | 1-gen-2021 | Mentegari, E; Bertoletti, F; Kissova, M; Zucca, E; Galli, S; Tagliavini, G; Garbelli, A; Maffia, A; Bione, S; Ferrari, E; d'Adda di Fagagna, F; Francia, S; Sabbioneda, S; Chen, Ly; Lingner, J; Bergoglio, V; Hoffmann, Js; Hubscher, U; Crespan, E; Maga, G | |
| Targeting ddx3x helicase activity with ba103 shows promising therapeutic effects in preclinical glioblastoma models | 1-gen-2021 | Brai A; Riva V; Clementi L; Falsitta L; Zamperini C; Sinigiani V; Festuccia C; Sabetta S; Aiello D; Roselli C; Garbelli A; Trivisani CI; Maccari L; Bugli F; Sanguinetti M; Calandro P; Chiariello M; Quaranta P; Botta L; Angelucci A; Maga G; Botta M. | |
| DDX3X Inhibitors, an Effective Way to Overcome HIV-1 Resistance Targeting Host Proteins | 1-gen-2020 | Brai A; Riva V; Saladini F; Zamperini C; Trivisani CI; Garbelli A; Pennisi C; Giannini A; Boccuto A; Bugli F; Martini M; Sanguinetti M; Zazzi M; Dreassi E; Botta M; Maga G. | |
| Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor | 1-gen-2020 | Brai, A; Boccuto, A; Monti, M; Marchi, S; Vicenti, I; Saladini, F; Trivisani, Ci; Pollutri, A; Trombetta, Cm; Montomoli, E; Riva, V; Garbelli, A; Nola, Em; Zazzi, M; Maga, G; Dreassi, E; Botta, M | |
| Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases | 1-gen-2020 | Riva V; Garbelli A; Casiraghi F; Arena F; Trivisani CI; Gagliardi A; Bini L; Schroeder M; Maffia A; Sabbioneda S; Maga G. | |
| Novel Insights into the Biochemical Mechanism of CK1epsilon and its Functional Interplay with DDX3X | 1-gen-2020 | Bono, B; Franco, G; Riva, V; Garbelli, A; Maga, G | |
| Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses | 1-gen-2020 | Riva V; Garbelli A; Brai A; Casiraghi F; Fazi R; Trivisani CI; Boccuto A; Saladini F; Vicenti I; Martelli F; Zazzi M; Giannecchini S; Dreassi E; Botta M; Maga G. | |
| DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection | 1-gen-2019 | Brai, A; Martelli, F; Riva, V; Garbelli, A; Fazi, R; Zamperini, C; Pollutri, A; Falsitta, L; Ronzini, S; Maccari, L; Maga, G; Giannecchini, S; Botta, M | |
| Synthesis and antiviral activity of novel 1,3,4-thiadiazole inhibitors of DDX3x | 1-gen-2019 | Brai A; Ronzini S; Riva V; Botta L; Zamperini C; Borgini M; Trivisani CI; Garbelli A; Pennisi C; Boccuto A; Saladini F; Zazzi M; Maga G; Botta M. | |
| How to win the HIV-1 drug resistance hurdle race: Running faster or jumping higher? | 1-gen-2017 | Garbelli, A; Riva, V; Crespan, E; Maga, G | |
| The power of enzyme kinetics in the drug development process | 1-gen-2013 | Samuele, A; Crespan, E; Garbelli, A; Bavagnoli, L; Maga, G | |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors | 1-gen-2012 | Radi, M; Falchi, F; Garbelli, A; Samuele, A; Bernardo, V; Paolucci, S; Baldanti, F; Schenone, S; Manetti, F; Maga, G; Botta, M | |
| A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication. | 1-gen-2011 | Garbelli A; Beermann S; Di Cicco G; Dietrich U; Maga G. | |
| Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents. | 1-gen-2011 | Crespan, E; Garbelli, A; Amoroso, A; Maga, G | |
| Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication. | 1-gen-2011 | Garbelli A; Radi M; Falchi F; Beermann S; Zanoli S; Manetti F; Dietrich U; Botta M; Maga G. | |
| The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection. | 1-gen-2011 | Bavagnoli, L; Dundon, Wg; Garbelli, A; Zecchin, B; Milani, A; Parakkal, G; Baldanti, F; Paolucci, S; Volmer, R; Tu, Y; Wu, C; Capua, I; Maga, G | |
| Inhibitors of human immunodeficiency virus-1 replication targeting the human dead-box polypeptide 3 (DDX3) RNA helicase | 1-gen-2010 | Maga G; Falchi F; Garbelli A; Radi M; Paolucci S; Baldanti F; Botta M | |
| Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3. | 1-gen-2008 | Maga, G; Falchi, F; Garbelli, A; Belfiore, A; Witvrouw, M; Manetti, F; Botta, M | |
| Expression, characterization of human DDX3 protein and construction of mutants. | 1-gen-2007 | Garbelli, A; Franca, R; Belfiore, A; Maga, G |