DELRE, PIETRO
DELRE, PIETRO
Istituto di Cristallografia - IC
DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation
2024 Alberga, Domenico; Lamanna, Giuseppe; Graziano, Giovanni; Delre, Pietro; Cristina Lomuscio, Maria; Corriero, Nicola; Ligresti, Alessia; Siliqi, Dritan; Saviano, Michele; Contino, Marialessandra; Stefanachi, Angela; Mangiatordi, GIUSEPPE FELICE
DypB peroxidase for aflatoxin removal: New insights into the toxin degradation process
2024 Mangini, V; Rosini, E; Caliandro, R; Mangiatordi, Gf; Delre, P; Sciancalepore, Ag; Pollegioni, L; Haidukowski, M; Mazzorana, M; Sumarah, Mw; Renaud, Jb; Flaig, R; Mulè, G; Belviso, Bd; Loi, M
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)
2024 Intranuovo, F; Majellaro, M; Mastropasqua, F; Delre, P; Abatematteo, Fs; Mangiatordi, Gf; Stefanachi, A; Brea, J; Loza, Mi; Riganti, C; Ligresti, A; Kumar, P; Esposito, D; Cristino, L; Nicois, A; González, L; Perrone, Mg; Colabufo, Na; Sotelo, E; Abate, C; Contino, M.
Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus
2024 Mori, Matteo; Cocorullo, Mario; Tresoldi, Andrea; Cazzaniga, Giulia; Gelain, Arianna; Stelitano, Giovanni; Chiarelli, Laurent R.; Tomaiuolo, Martina; Delre, Pietro; Mangiatordi, Giuseppe F.; Garofalo, Mariangela; Cassetta, Alberto; Covaceuszach, Sonia; Villa, Stefania; Meneghetti, Fiorella
Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization
2024 La Spada, Gabriella; Miniero, Daniela Valeria; Rullo, Mariagrazia; Cipolloni, Marco; Delre, Pietro; Colliva, Carolina; Colella, Marco; Leonetti, Francesco; Liuzzi, Grazia Maria; Mangiatordi, Giuseppe Felice; Giacchè, Nicola; Pisani, Leonardo
A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach
2023 Abatematteo Francesca, Serena; Delre, Pietro; Mercurio, Ivan; Rezelj Veronica, V; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo Nicola, Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, GIUSEPPE FELICE; Abate, Carmen
ALPACA: A machine Learning Platform for Affinity and selectivity profiling of CAnnabinoids receptors modulators
2023 Delre, Pietro; Contino, Marialessandra; Alberga, Domenico; Saviano, Michele; Corriero, Nicola; Mangiatordi, GIUSEPPE FELICE
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis
2023 Lomuscio, MARIA CRISTINA; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo Nicola, Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE
Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors
2023 Rullo, Mariagrazia; La Spada, Gabriella; Miniero Daniela, Valeria; Gottinger, Andrea; Catto, Marco; Delre, Pietro; Mastromarino, Margherita; Latronico, Tiziana; Marchese, Sara; Mangiatordi, GIUSEPPE FELICE; Binda, Claudia; Linusson, Anna; Liuzzi Grazia, Maria; Pisani, Leonardo
Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers
2023 Sarcina, Lucia; Delre, Pietro; Graziano, Giovanni; Stefanachi, Angela; Blasi, Davide; Picca Rosaria, A; DI FRANCO, Cinzia; Leonetti, Francesco; Scamarcio, Gaetano; Bollella, Paolo; Mangiatordi Giuseppe, F; Macchia, Eleonora; Torsi, Luisa
Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4?-piperidin]-1?-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of ? Receptors via Fluorescence-Based Techniques
2023 Abatematteo Francesca, Serena; Majellaro, Maria; Montsch, Bianca; Prietodíaz, Rubén; Niso, Mauro; Contino, Marialessandra; Stefanachi, Angela; Riganti, Chiara; Mangiatordi, GIUSEPPE FELICE; Delre, Pietro; Heffeter, Petra; Sotelo, Eddy; Abate, Carmen
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels
2023 Farinato, Alessandro; Cavalluzzi Maria, Maddalena; Altamura, Concetta; Campanale, Carmen; Laghetti, Paola; Saltarella, Ilaria; Delre, Pietro; Barbault, Arthur; Tarantino, Nancy; Milani, Gualtiero; Rotondo Natalie, Paola; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Pierno, Sabata; Mangiatordi, GIUSEPPE FELICE; Lentini, Giovanni; Desaphy Jean, François
Endocannabinoid Degradation Enzyme Inhibitors as Potential Antipsychotics: A Medicinal Chemistry Perspective
2023 Mangiatordi, GIUSEPPE FELICE; Cavalluzzi Maria, Maddalena; Delre, Pietro; Lamanna, Giuseppe; Lumuscio Maria, Cristina; Saviano, Michele; Majoral Jean, Pierre; Mignani, Serge; Duranti, Andrea; Lentini, Giovanni
GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design
2023 Lamanna, Giuseppe; Delre, Pietro; Marcou, Gilles; Saviano, Michele; Varnek, Alexandre; Horvath, Dragos; Mangiatordi, GIUSEPPE FELICE
hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation
2023 Milani, Gualtiero; Budriesi, Roberta; Tavazzani, Elisa; Cavalluzzi Maria, Maddalena; Mattioli Laura, Beatrice; Miniero Daniela, Valeria; Delre, Pietro; Belviso, BENNY DANILO; Denegri, Marco; Cuocci, Corrado; Rotondo Natalie, Paola; De Palma, Annalisa; Gualdani, Roberta; Caliandroro, Rocco; Mangiatordi, GIUSEPPE FELICE; Felice, Giuseppe; Kumawat, Amit; Camilloni, Carlo; Priori, Silvia; Lentini, Giovanni
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R)
2023 Graziano, G; Delre, P; Carofiglio, F; Brea, J; Ligresti, A; Kostrzewa, M; Riganti, C; Gioegallo, C; Majellaro, M; Nicolotti, O; Colabufo, Na; Abate, C; Loza, Mi; Sotelo, E; Mangiatordi, Gf; Contino, M; Stefanachi, A; Leonetti, F
Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria
2023 Mori, M.; Stelitano, G.; Cazzaniga, G.; Gelain, A.; Tresoldi, A.; Cocorullo, M.; Roversi, M.; Chiarelli, L. R.; Tomaiuolo, M.; Delre, P.; Mangiatordi, G. F.; Griego, A.; Rizzello, L.; Cassetta, A.; Covaceuszach, S.; Villa, S.; Meneghetti, F.
A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS
2022 Spinetti, E; Delre, P; Saviano, M; Siliqi, D; Lattanzi, G; Mangiatordi, Gf
DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues
2022 Creanza, TERESA MARIA; Lamanna, Giuseppe; Delre, Pietro; Contino, Marialessandra; Corriero, Nicola; Saviano, Michele; Mangiatordi, GIUSEPPE FELICE; Ancona, Nicola
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase
2022 Intranuovo, Francesca; Brunetti, Leonardo; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Loza Maria, Isabel; Sotelo, Eddy; Saviano, Michele; Colabufo Nicola, Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation | 1-gen-2024 | Alberga, Domenico; Lamanna, Giuseppe; Graziano, Giovanni; Delre, Pietro; Cristina Lomuscio, Maria; Corriero, Nicola; Ligresti, Alessia; Siliqi, Dritan; Saviano, Michele; Contino, Marialessandra; Stefanachi, Angela; Mangiatordi, GIUSEPPE FELICE | |
| DypB peroxidase for aflatoxin removal: New insights into the toxin degradation process | 1-gen-2024 | Mangini, V; Rosini, E; Caliandro, R; Mangiatordi, Gf; Delre, P; Sciancalepore, Ag; Pollegioni, L; Haidukowski, M; Mazzorana, M; Sumarah, Mw; Renaud, Jb; Flaig, R; Mulè, G; Belviso, Bd; Loi, M | |
| N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R) | 1-gen-2024 | Intranuovo, F; Majellaro, M; Mastropasqua, F; Delre, P; Abatematteo, Fs; Mangiatordi, Gf; Stefanachi, A; Brea, J; Loza, Mi; Riganti, C; Ligresti, A; Kumar, P; Esposito, D; Cristino, L; Nicois, A; González, L; Perrone, Mg; Colabufo, Na; Sotelo, E; Abate, C; Contino, M. | |
| Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus | 1-gen-2024 | Mori, Matteo; Cocorullo, Mario; Tresoldi, Andrea; Cazzaniga, Giulia; Gelain, Arianna; Stelitano, Giovanni; Chiarelli, Laurent R.; Tomaiuolo, Martina; Delre, Pietro; Mangiatordi, Giuseppe F.; Garofalo, Mariangela; Cassetta, Alberto; Covaceuszach, Sonia; Villa, Stefania; Meneghetti, Fiorella | |
| Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization | 1-gen-2024 | La Spada, Gabriella; Miniero, Daniela Valeria; Rullo, Mariagrazia; Cipolloni, Marco; Delre, Pietro; Colliva, Carolina; Colella, Marco; Leonetti, Francesco; Liuzzi, Grazia Maria; Mangiatordi, Giuseppe Felice; Giacchè, Nicola; Pisani, Leonardo | |
| A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach | 1-gen-2023 | Abatematteo Francesca, Serena; Delre, Pietro; Mercurio, Ivan; Rezelj Veronica, V; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo Nicola, Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, GIUSEPPE FELICE; Abate, Carmen | |
| ALPACA: A machine Learning Platform for Affinity and selectivity profiling of CAnnabinoids receptors modulators | 1-gen-2023 | Delre, Pietro; Contino, Marialessandra; Alberga, Domenico; Saviano, Michele; Corriero, Nicola; Mangiatordi, GIUSEPPE FELICE | |
| AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis | 1-gen-2023 | Lomuscio, MARIA CRISTINA; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo Nicola, Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE | |
| Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors | 1-gen-2023 | Rullo, Mariagrazia; La Spada, Gabriella; Miniero Daniela, Valeria; Gottinger, Andrea; Catto, Marco; Delre, Pietro; Mastromarino, Margherita; Latronico, Tiziana; Marchese, Sara; Mangiatordi, GIUSEPPE FELICE; Binda, Claudia; Linusson, Anna; Liuzzi Grazia, Maria; Pisani, Leonardo | |
| Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers | 1-gen-2023 | Sarcina, Lucia; Delre, Pietro; Graziano, Giovanni; Stefanachi, Angela; Blasi, Davide; Picca Rosaria, A; DI FRANCO, Cinzia; Leonetti, Francesco; Scamarcio, Gaetano; Bollella, Paolo; Mangiatordi Giuseppe, F; Macchia, Eleonora; Torsi, Luisa | |
| Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4?-piperidin]-1?-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of ? Receptors via Fluorescence-Based Techniques | 1-gen-2023 | Abatematteo Francesca, Serena; Majellaro, Maria; Montsch, Bianca; Prietodíaz, Rubén; Niso, Mauro; Contino, Marialessandra; Stefanachi, Angela; Riganti, Chiara; Mangiatordi, GIUSEPPE FELICE; Delre, Pietro; Heffeter, Petra; Sotelo, Eddy; Abate, Carmen | |
| Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels | 1-gen-2023 | Farinato, Alessandro; Cavalluzzi Maria, Maddalena; Altamura, Concetta; Campanale, Carmen; Laghetti, Paola; Saltarella, Ilaria; Delre, Pietro; Barbault, Arthur; Tarantino, Nancy; Milani, Gualtiero; Rotondo Natalie, Paola; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Pierno, Sabata; Mangiatordi, GIUSEPPE FELICE; Lentini, Giovanni; Desaphy Jean, François | |
| Endocannabinoid Degradation Enzyme Inhibitors as Potential Antipsychotics: A Medicinal Chemistry Perspective | 1-gen-2023 | Mangiatordi, GIUSEPPE FELICE; Cavalluzzi Maria, Maddalena; Delre, Pietro; Lamanna, Giuseppe; Lumuscio Maria, Cristina; Saviano, Michele; Majoral Jean, Pierre; Mignani, Serge; Duranti, Andrea; Lentini, Giovanni | |
| GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design | 1-gen-2023 | Lamanna, Giuseppe; Delre, Pietro; Marcou, Gilles; Saviano, Michele; Varnek, Alexandre; Horvath, Dragos; Mangiatordi, GIUSEPPE FELICE | |
| hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation | 1-gen-2023 | Milani, Gualtiero; Budriesi, Roberta; Tavazzani, Elisa; Cavalluzzi Maria, Maddalena; Mattioli Laura, Beatrice; Miniero Daniela, Valeria; Delre, Pietro; Belviso, BENNY DANILO; Denegri, Marco; Cuocci, Corrado; Rotondo Natalie, Paola; De Palma, Annalisa; Gualdani, Roberta; Caliandroro, Rocco; Mangiatordi, GIUSEPPE FELICE; Felice, Giuseppe; Kumawat, Amit; Camilloni, Carlo; Priori, Silvia; Lentini, Giovanni | |
| N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) | 1-gen-2023 | Graziano, G; Delre, P; Carofiglio, F; Brea, J; Ligresti, A; Kostrzewa, M; Riganti, C; Gioegallo, C; Majellaro, M; Nicolotti, O; Colabufo, Na; Abate, C; Loza, Mi; Sotelo, E; Mangiatordi, Gf; Contino, M; Stefanachi, A; Leonetti, F | |
| Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria | 1-gen-2023 | Mori, M.; Stelitano, G.; Cazzaniga, G.; Gelain, A.; Tresoldi, A.; Cocorullo, M.; Roversi, M.; Chiarelli, L. R.; Tomaiuolo, M.; Delre, P.; Mangiatordi, G. F.; Griego, A.; Rizzello, L.; Cassetta, A.; Covaceuszach, S.; Villa, S.; Meneghetti, F. | |
| A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS | 1-gen-2022 | Spinetti, E; Delre, P; Saviano, M; Siliqi, D; Lattanzi, G; Mangiatordi, Gf | |
| DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues | 1-gen-2022 | Creanza, TERESA MARIA; Lamanna, Giuseppe; Delre, Pietro; Contino, Marialessandra; Corriero, Nicola; Saviano, Michele; Mangiatordi, GIUSEPPE FELICE; Ancona, Nicola | |
| Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase | 1-gen-2022 | Intranuovo, Francesca; Brunetti, Leonardo; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Loza Maria, Isabel; Sotelo, Eddy; Saviano, Michele; Colabufo Nicola, Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra |