DELRE, PIETRO
DELRE, PIETRO
DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation
2024 Alberga, Domenico; Lamanna, Giuseppe; Graziano, Giovanni; Delre, Pietro; Cristina Lomuscio, Maria; Corriero, Nicola; Ligresti, Alessia; Siliqi, Dritan; Saviano, Michele; Contino, Marialessandra; Stefanachi, Angela; Mangiatordi, GIUSEPPE FELICE
A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach
2023 Abatematteo, Francesca Serena; Delre, Pietro; Mercurio, Ivan; Rezelj, Veronica V.; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo, Nicola Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, Giuseppe Felice; Abate, Carmen
ALPACA: A machine Learning Platform for Affinity and selectivity profiling of CAnnabinoids receptors modulators
2023 Delre, Pietro; Contino, Marialessandra; Alberga, Domenico; Saviano, Michele; Corriero, Nicola; Mangiatordi, GIUSEPPE FELICE
AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis
2023 Lomuscio, MARIA CRISTINA; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo Nicola, Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE
Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors
2023 Rullo, Mariagrazia; La Spada, Gabriella; Miniero, Daniela Valeria; Gottinger, Andrea; Catto, Marco; Delre, Pietro; Mastromarino, Margherita; Latronico, Tiziana; Marchese, Sara; Mangiatordi, Giuseppe Felice; Binda, Claudia; Linusson, Anna; Liuzzi, Grazia Maria; Pisani, Leonardo
Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers
2023 Sarcina, Lucia; Delre, Pietro; Graziano, Giovanni; Stefanachi, Angela; Blasi, Davide; Picca Rosaria, A; DI FRANCO, Cinzia; Leonetti, Francesco; Scamarcio, Gaetano; Bollella, Paolo; Mangiatordi Giuseppe, F; Macchia, Eleonora; Torsi, Luisa
Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4?-piperidin]-1?-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of ? Receptors via Fluorescence-Based Techniques
2023 Abatematteo, Francesca Serena; Majellaro, Maria; Montsch, Bianca; PrietoDíaz, Rubén; Niso, Mauro; Contino, Marialessandra; Stefanachi, Angela; Riganti, Chiara; Mangiatordi, Giuseppe Felice; Delre, Pietro; Heffeter, Petra; Sotelo, Eddy; Abate, Carmen
Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels
2023 Farinato, Alessandro; Cavalluzzi, Maria Maddalena; Altamura, Concetta; Campanale, Carmen; Laghetti, Paola; Saltarella, Ilaria; Delre, Pietro; Barbault, Arthur; Tarantino, Nancy; Milani, Gualtiero; Rotondo, Natalie Paola; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Pierno, Sabata; Mangiatordi, Giuseppe Felice; Lentini, Giovanni; Desaphy, Jean François
DypB peroxidase for aflatoxin removal: New insights into the toxin degradation process
2023 Mangini V; Rosini E; Caliandro R; Mangiatordi GF; Delre P; Sciancalepore AG; Pollegioni L; Haidukowski M; Mazzorana M; Sumarah MW; Renaud JB; Flaig R; Mulè G; Belviso BD; Loi M.
Endocannabinoid Degradation Enzyme Inhibitors as Potential Antipsychotics: A Medicinal Chemistry Perspective
2023 Mangiatordi, Giuseppe Felice; Cavalluzzi, Maria Maddalena; Delre, Pietro; Lamanna, Giuseppe; Lumuscio, Maria Cristina; Saviano, Michele; Majoral, Jean Pierre; Mignani, Serge; Duranti, Andrea; Lentini, Giovanni
GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design
2023 Lamanna, Giuseppe; Delre, Pietro; Marcou, Gilles; Saviano, Michele; Varnek, Alexandre; Horvath, Dragos; Mangiatordi, GIUSEPPE FELICE
hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation
2023 Milani Gualtiero; Budriesi Roberta; Tavazzani Elisa; Cavalluzzi Maria Maddalena; Mattioli Laura Beatrice; Miniero Daniela Valeria; Delre Pietro; Belviso Benny Danilo; Denegri Marco; Cuocci Corrado; Rotondo Natalie Paola; De Palma Annalisa; Gualdani Roberta; Caliandroro Rocco ; Mangiatordi; Giuseppe Felice; Kumawat Amit; Camilloni Carlo; Priori Silvia;; Lentini Giovanni
Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria
2023 Mori M.; Stelitano G.; Cazzaniga G.; Gelain A.; Tresoldi A.; Cocorullo M.; Roversi M.; Chiarelli L.R.; Tomaiuolo M.; Delre P.; Mangiatordi G.F.; Griego A.; Rizzello L.; Cassetta A.; Covaceuszach S.; Villa S.; Meneghetti F.
A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS
2022 Spinetti E.; Delre P.; Saviano M.; Siliqi D.; Lattanzi G.; Mangiatordi G.F.
DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues
2022 Creanza, Teresa Maria; Lamanna, Giuseppe; Delre, Pietro; Contino, Marialessandra; Corriero, Nicola; Saviano, Michele; Mangiatordi, Giuseppe Felice; Ancona, Nicola
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase
2022 Intranuovo, Francesca; Brunetti, Leonardo; DelRe, Pietro; Mangiatordi, Giuseppe Felice; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Loza, Maria Isabel; Sotelo, Eddy; Saviano, Michele; Colabufo, Nicola Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra
Ligand-based prediction of hERG-mediated cardiotoxicity based on the integration of different machine learning techniques
2022 Delre, Pietro; Lavado, Giovanna J.; Lamanna, Giuseppe; Saviano, Michele; Roncaglioni, Alessandra; Benfenati, Emilio; Mangiatordi, Giuseppe Felice; Gadaleta, Domenico
Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study
2021 Creanza, Tm; Delre, P; Ancona, N; Lentini, G; Saviano, M; Mangiatordi, Gf
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation | 1-gen-2024 | Alberga, Domenico; Lamanna, Giuseppe; Graziano, Giovanni; Delre, Pietro; Cristina Lomuscio, Maria; Corriero, Nicola; Ligresti, Alessia; Siliqi, Dritan; Saviano, Michele; Contino, Marialessandra; Stefanachi, Angela; Mangiatordi, GIUSEPPE FELICE | |
| A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach | 1-gen-2023 | Abatematteo, Francesca Serena; Delre, Pietro; Mercurio, Ivan; Rezelj, Veronica V.; Siliqi, Dritan; Beaucourt, Stephanie; Lattanzi, Gianluca; Colabufo, Nicola Antonio; Leopoldo, Marcello; Saviano, Michele; Vignuzzi, Marco; Mangiatordi, Giuseppe Felice; Abate, Carmen | |
| ALPACA: A machine Learning Platform for Affinity and selectivity profiling of CAnnabinoids receptors modulators | 1-gen-2023 | Delre, Pietro; Contino, Marialessandra; Alberga, Domenico; Saviano, Michele; Corriero, Nicola; Mangiatordi, GIUSEPPE FELICE | |
| AMALPHI: A Machine Learning Platform for Predicting Drug-Induced PhospholIpidosis | 1-gen-2023 | Lomuscio, MARIA CRISTINA; Abate, Carmen; Alberga, Domenico; Laghezza, Antonio; Corriero, Nicola; Colabufo Nicola, Antonio; Saviano, Michele; Delre, Pietro; Mangiatordi, GIUSEPPE FELICE | |
| Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors | 1-gen-2023 | Rullo, Mariagrazia; La Spada, Gabriella; Miniero, Daniela Valeria; Gottinger, Andrea; Catto, Marco; Delre, Pietro; Mastromarino, Margherita; Latronico, Tiziana; Marchese, Sara; Mangiatordi, Giuseppe Felice; Binda, Claudia; Linusson, Anna; Liuzzi, Grazia Maria; Pisani, Leonardo | |
| Controlling the Binding Efficiency of Surface Confined Antibodies through the Design of Mixed Self-Assembled Monolayers | 1-gen-2023 | Sarcina, Lucia; Delre, Pietro; Graziano, Giovanni; Stefanachi, Angela; Blasi, Davide; Picca Rosaria, A; DI FRANCO, Cinzia; Leonetti, Francesco; Scamarcio, Gaetano; Bollella, Paolo; Mangiatordi Giuseppe, F; Macchia, Eleonora; Torsi, Luisa | |
| Development of Fluorescent 4-[4-(3H-Spiro[isobenzofuran-1,4?-piperidin]-1?-yl)butyl]indolyl Derivatives as High-Affinity Probes to Enable the Study of ? Receptors via Fluorescence-Based Techniques | 1-gen-2023 | Abatematteo, Francesca Serena; Majellaro, Maria; Montsch, Bianca; PrietoDíaz, Rubén; Niso, Mauro; Contino, Marialessandra; Stefanachi, Angela; Riganti, Chiara; Mangiatordi, Giuseppe Felice; Delre, Pietro; Heffeter, Petra; Sotelo, Eddy; Abate, Carmen | |
| Development of Riluzole Analogs with Improved Use-Dependent Inhibition of Skeletal Muscle Sodium Channels | 1-gen-2023 | Farinato, Alessandro; Cavalluzzi, Maria Maddalena; Altamura, Concetta; Campanale, Carmen; Laghetti, Paola; Saltarella, Ilaria; Delre, Pietro; Barbault, Arthur; Tarantino, Nancy; Milani, Gualtiero; Rotondo, Natalie Paola; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Pierno, Sabata; Mangiatordi, Giuseppe Felice; Lentini, Giovanni; Desaphy, Jean François | |
| DypB peroxidase for aflatoxin removal: New insights into the toxin degradation process | 1-gen-2023 | Mangini V; Rosini E; Caliandro R; Mangiatordi GF; Delre P; Sciancalepore AG; Pollegioni L; Haidukowski M; Mazzorana M; Sumarah MW; Renaud JB; Flaig R; Mulè G; Belviso BD; Loi M. | |
| Endocannabinoid Degradation Enzyme Inhibitors as Potential Antipsychotics: A Medicinal Chemistry Perspective | 1-gen-2023 | Mangiatordi, Giuseppe Felice; Cavalluzzi, Maria Maddalena; Delre, Pietro; Lamanna, Giuseppe; Lumuscio, Maria Cristina; Saviano, Michele; Majoral, Jean Pierre; Mignani, Serge; Duranti, Andrea; Lentini, Giovanni | |
| GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design | 1-gen-2023 | Lamanna, Giuseppe; Delre, Pietro; Marcou, Gilles; Saviano, Michele; Varnek, Alexandre; Horvath, Dragos; Mangiatordi, GIUSEPPE FELICE | |
| hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation | 1-gen-2023 | Milani Gualtiero; Budriesi Roberta; Tavazzani Elisa; Cavalluzzi Maria Maddalena; Mattioli Laura Beatrice; Miniero Daniela Valeria; Delre Pietro; Belviso Benny Danilo; Denegri Marco; Cuocci Corrado; Rotondo Natalie Paola; De Palma Annalisa; Gualdani Roberta; Caliandroro Rocco ; Mangiatordi; Giuseppe Felice; Kumawat Amit; Camilloni Carlo; Priori Silvia;; Lentini Giovanni | |
| Targeting Siderophore-Mediated Iron Uptake in M. abscessus: A New Strategy to Limit the Virulence of Non-Tuberculous Mycobacteria | 1-gen-2023 | Mori M.; Stelitano G.; Cazzaniga G.; Gelain A.; Tresoldi A.; Cocorullo M.; Roversi M.; Chiarelli L.R.; Tomaiuolo M.; Delre P.; Mangiatordi G.F.; Griego A.; Rizzello L.; Cassetta A.; Covaceuszach S.; Villa S.; Meneghetti F. | |
| A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS | 1-gen-2022 | Spinetti E.; Delre P.; Saviano M.; Siliqi D.; Lattanzi G.; Mangiatordi G.F. | |
| DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues | 1-gen-2022 | Creanza, Teresa Maria; Lamanna, Giuseppe; Delre, Pietro; Contino, Marialessandra; Corriero, Nicola; Saviano, Michele; Mangiatordi, Giuseppe Felice; Ancona, Nicola | |
| Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase | 1-gen-2022 | Intranuovo, Francesca; Brunetti, Leonardo; DelRe, Pietro; Mangiatordi, Giuseppe Felice; Stefanachi, Angela; Laghezza, Antonio; Niso, Mauro; Leonetti, Francesco; Loiodice, Fulvio; Ligresti, Alessia; Kostrzewa, Magdalena; Brea, Jose; Loza, Maria Isabel; Sotelo, Eddy; Saviano, Michele; Colabufo, Nicola Antonio; Riganti, Chiara; Abate, Carmen; Contino, Marialessandra | |
| Ligand-based prediction of hERG-mediated cardiotoxicity based on the integration of different machine learning techniques | 1-gen-2022 | Delre, Pietro; Lavado, Giovanna J.; Lamanna, Giuseppe; Saviano, Michele; Roncaglioni, Alessandra; Benfenati, Emilio; Mangiatordi, Giuseppe Felice; Gadaleta, Domenico | |
| Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study | 1-gen-2021 | Creanza, Tm; Delre, P; Ancona, N; Lentini, G; Saviano, M; Mangiatordi, Gf |