CARLOMAGNO, FRANCESCA
 Distribuzione geografica
Continente #
AS - Asia 1.142
NA - Nord America 674
SA - Sud America 300
EU - Europa 213
AF - Africa 17
OC - Oceania 2
Totale 2.348
Nazione #
US - Stati Uniti d'America 647
SG - Singapore 507
CN - Cina 247
BR - Brasile 246
HK - Hong Kong 123
VN - Vietnam 122
FR - Francia 64
NL - Olanda 39
KR - Corea 36
AR - Argentina 26
DE - Germania 25
JP - Giappone 25
GB - Regno Unito 20
IT - Italia 19
BD - Bangladesh 16
EC - Ecuador 13
CA - Canada 11
FI - Finlandia 11
IN - India 11
ID - Indonesia 10
MX - Messico 10
IQ - Iraq 8
CO - Colombia 7
IL - Israele 6
ES - Italia 5
UA - Ucraina 5
ZA - Sudafrica 5
KZ - Kazakistan 4
OM - Oman 4
RU - Federazione Russa 4
AT - Austria 3
EG - Egitto 3
HN - Honduras 3
LB - Libano 3
LT - Lituania 3
MA - Marocco 3
PL - Polonia 3
PY - Paraguay 3
SE - Svezia 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AU - Australia 2
CL - Cile 2
CZ - Repubblica Ceca 2
IE - Irlanda 2
PK - Pakistan 2
SA - Arabia Saudita 2
TN - Tunisia 2
TW - Taiwan 2
BG - Bulgaria 1
BH - Bahrain 1
BO - Bolivia 1
BW - Botswana 1
BY - Bielorussia 1
CY - Cipro 1
DZ - Algeria 1
GA - Gabon 1
GT - Guatemala 1
HR - Croazia 1
JM - Giamaica 1
JO - Giordania 1
KW - Kuwait 1
LK - Sri Lanka 1
LY - Libia 1
MD - Moldavia 1
NP - Nepal 1
PE - Perù 1
PT - Portogallo 1
QA - Qatar 1
SR - Suriname 1
TH - Thailandia 1
TJ - Tagikistan 1
TT - Trinidad e Tobago 1
Totale 2.348
Città #
Santa Clara 314
Singapore 281
Hong Kong 122
Hefei 77
Beijing 61
Lauterbourg 55
San Jose 49
Ho Chi Minh City 40
Ashburn 38
Seoul 36
Hanoi 31
Los Angeles 24
Tokyo 19
São Paulo 18
Frankfurt am Main 11
Helsinki 11
New York 11
Rio de Janeiro 9
Buffalo 8
Belo Horizonte 7
Quận Bình Thạnh 7
Baghdad 6
Dhaka 6
London 6
Minamishinagawa 6
Montreal 6
Biên Hòa 5
Brasília 5
Campinas 5
Da Nang 5
Guayaquil 5
Haiphong 5
Nuremberg 5
Portsmouth 5
Dallas 4
Denver 4
Düsseldorf 4
Orem 4
Phoenix 4
Salvador 4
Sumaré 4
Acalanes Ridge 3
Barra do Piraí 3
Curitiba 3
Diadema 3
Falkenstein 3
Hangzhou 3
Johannesburg 3
José C. Paz 3
Madrid 3
Poplar 3
Quito 3
Rome 3
Seeb 3
Shanghai 3
Stockholm 3
São José 3
Tashkent 3
Uberaba 3
Vienna 3
Viçosa 3
Ahmedabad 2
Alexandria 2
Alfenas 2
Almaty 2
Amsterdam 2
Asunción 2
Atlanta 2
Bauru 2
Belford Roxo 2
Bengaluru 2
Charlotte 2
Chennai 2
Chicago 2
Cleveland 2
Diamantina 2
Dourados 2
Durban 2
Kyiv 2
Magé 2
Manchester 2
Mexico City 2
Mumbai 2
Naples 2
Nova Serrana 2
Patos de Minas 2
Pelotas 2
Philadelphia 2
Phủ Lý 2
Piracicaba 2
Piscataway 2
Porto Alegre 2
Prague 2
Recife 2
Santiago de Cali 2
Sorocaba 2
Suzano 2
Sydney 2
São Lourenço do Sul 2
São Luís 2
Totale 1.465
Nome #
Association between DNA methylation profile and malignancy in follicular-patterned thyroid neoplasms 113
ZD6474, an Orally Available Inhibitor of KDR Tyrosine Kinase Activity, Efficiently Blocks Oncogenic RET Kinases. 76
Attacking cancer with molecularly targeted agents Editorial overview 68
Genetic alterations in differentiated thyroid cancer: what can be expected for gene expression profiling of thyroid carcinomas 58
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells 55
Identification of RET kinase inhibitors as potential new treatment for sporadic and inherited thyroid cancer. 52
NCOA4 deficiency impairs systemic iron homeostasis 51
Bioisosteric discovery of npa101.3, a second-generation ret/vegfr2 inhibitor optimized for single-agent polypharmacology 50
Functional characterization of a novel FGFR1OP-RET rearrangement in hematopoietic malignancies 49
Iron and ferritin modulate MHC Class i expression and NK cell recognition 48
The receptor-type protein tyrosine phosphatase J antagonizes the biochemical and biological effects of RET-derived oncoproteins. 48
Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases 48
NCOA4-mediated Ferritinophagy in Macrophages Is Crucial to Sustain Erythropoiesis in Mice 47
Fragment-Based Discovery of a Dual pan-RET/VEGFR2 Kinase Inhibitor Optimized for Single-Agent Polypharmacology 46
Identification of novel small molecule inhibitors of oncogenic RET kinase 46
The molecular basis for RET tyrosine-kinase inhibitors in thyroid cancer 45
Regulation of p27Kip1 protein levels contributes to mitogenic effects of the RET/PTC kinase in thyroid carcinoma cells. 45
Identification of two novel RET kinase inhibitors through MCR-based drug discovery: Design, synthesis and evaluation 44
Ret-mediated mitogenesis requires Src kinase activity 43
D898_E901 RET Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms 43
Ret gene fusions in malignancies of the thyroid and other tissues 43
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application 42
RET is a heat shock protein 90 (HSP90) client protein and is knocked down upon HSP90 pharmacological block. 41
Efficient inhibition of RET/papillary thyroid carcinoma oncogenic kinases by 4-amino-5-(4-chloro-phenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2). 40
Discovery of pyrazolo-thieno[3,2-d]pyrimidinylamino-phenyl acetamides as type-II pan-tropomyosin receptor kinase (TRK) inhibitors: Design, synthesis, and biological evaluation 40
RET/PTC activation in human thyroid carcinomas 40
The tyrosine kinase inhibitor ZD6474 blocks proliferation of RET mutant medullary thyroid carcinoma cells. 39
Oncogenic rearrangements driving ionizing radiation-associated human cancer 38
BRAF is a therapeutic target in aggressive thyroid carcinoma. 38
Receptor tyrosine kinase inhibitors in thyroid cancer. 38
Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose 38
Growth factor transduction pathways: Paradigm of anti-neoplastic targeted therapy 37
Mitogenic effects of the up-regulation of minichromosome maintenance proteins in anaplastic thyroid carcinoma. 37
Targeting RET Kinase in Thyroid Cancer 36
Tamoxifen erythroid toxicity revealed by studying the role of nuclear receptor co-activator 4 in erythropoiesis 34
Pros and cons of cellular studies in developing new drugs for thyroid cancers. 33
Central role of RET in thyroid cancer 32
The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype. 31
Peroxiredoxin-2: A Novel Regulator of Iron Homeostasis in Ineffective Erythropoiesis 31
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 31
Potent mitogenicity of the RET/PTC3 oncogene correlates with its prevalence in tall-cell variant of papillary thyroid carcinoma. 30
Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival 30
Constitutive and AP20187-induced Ret activation in photoreceptors does not protect from light-induced damage. 29
BAY 43-9006 inhibition of oncogenic RET mutants. 29
Minireview: RET: normal and abnormal functions 28
The oncogenic activity of RET point mutants for follicular thyroid cells may account for the occurrence of papillary thyroid carcinoma in patients affected by familial medullary thyroid carcinoma. 28
Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor beta gatekeeper mutants. 27
Receptor tyrosine kinases as targets for anticancer therapeutics. 26
The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret. 25
Only the substitution of methionine 918 with a threonine and not with other residues activates RET transforming potential 25
New therapeutic approaches to treat medullary thyroid carcinoma. 25
Identification of Polo-like kinase 1 as a potential therapeutic target in anaplastic thyroid carcinoma. 24
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKs): Evidence for a divergence of the ERKs and JNKs pathways induced by Ret 24
Glial cell line-Derived Neurotrophic Factor differentially stimulates Ret mutants associated with the Multiple Endocrine Neoplasia type 2 syndromes and Hirschsprung's disease 24
Different mutations of the RET gene cause different human tumoral diseases 24
Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474. 23
Dysfunction of the RET receptor in human cancer. 22
Molecular biology of the MEN2 gene 22
Receptor- and non-receptor tyrosine kinases induce processing of the amyloid precursor protein: role of the low-density lipoprotein receptor-related protein. 22
The kinase inhibitor PP1 blocks tumorigenesis induced by RET oncogenes. 21
Cloning and molecular characterization of a novel gene strongly induced by the adenovirus E1A gene in rat thyroid cells 20
Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B 20
Clinical case seminar: in vivo and in vitro characterization of a novel germline RET mutation associated with low-penetrant nonaggressive familial medullary thyroid carcinoma. 17
Totale 2.379
Categoria #
all - tutte 7.232
article - articoli 7.232
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 14.464


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202416 0 0 0 0 0 0 0 0 1 0 9 6
2024/2025998 10 3 71 32 299 35 30 51 25 60 185 197
2025/20261.365 53 215 101 212 256 72 183 83 59 85 46 0
Totale 2.379