MIELE, CLAUDIA
 Distribuzione geografica
Continente #
AS - Asia 3.437
NA - Nord America 1.777
EU - Europa 846
SA - Sud America 692
AF - Africa 61
OC - Oceania 10
Totale 6.823
Nazione #
US - Stati Uniti d'America 1.684
SG - Singapore 1.411
CN - Cina 776
BR - Brasile 555
HK - Hong Kong 415
VN - Vietnam 357
IT - Italia 260
FR - Francia 203
KR - Corea 144
NL - Olanda 134
BD - Bangladesh 81
DE - Germania 55
AR - Argentina 50
IN - India 50
GB - Regno Unito 49
JP - Giappone 46
CA - Canada 44
EC - Ecuador 31
FI - Finlandia 26
ID - Indonesia 25
MX - Messico 24
IL - Israele 23
ZA - Sudafrica 23
PL - Polonia 19
IQ - Iraq 17
TR - Turchia 15
CO - Colombia 14
SA - Arabia Saudita 14
PY - Paraguay 12
RU - Federazione Russa 11
UA - Ucraina 11
AU - Australia 10
PK - Pakistan 10
SE - Svezia 10
LT - Lituania 9
ES - Italia 8
UZ - Uzbekistan 8
BO - Bolivia 7
CL - Cile 7
JM - Giamaica 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
IE - Irlanda 6
PE - Perù 6
VE - Venezuela 6
AL - Albania 5
DZ - Algeria 5
EG - Egitto 5
MA - Marocco 5
NP - Nepal 5
AZ - Azerbaigian 4
CR - Costa Rica 4
GR - Grecia 4
HU - Ungheria 4
KE - Kenya 4
PT - Portogallo 4
RO - Romania 4
TH - Thailandia 4
UY - Uruguay 4
AT - Austria 3
GA - Gabon 3
MY - Malesia 3
NI - Nicaragua 3
PH - Filippine 3
TT - Trinidad e Tobago 3
AO - Angola 2
BY - Bielorussia 2
CH - Svizzera 2
CY - Cipro 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
GE - Georgia 2
GH - Ghana 2
HR - Croazia 2
JO - Giordania 2
KZ - Kazakistan 2
LB - Libano 2
LU - Lussemburgo 2
LV - Lettonia 2
MN - Mongolia 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
AI - Anguilla 1
AM - Armenia 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BZ - Belize 1
DJ - Gibuti 1
DO - Repubblica Dominicana 1
EE - Estonia 1
ET - Etiopia 1
GT - Guatemala 1
HN - Honduras 1
IR - Iran 1
KG - Kirghizistan 1
KH - Cambogia 1
LK - Sri Lanka 1
MG - Madagascar 1
Totale 6.818
Città #
Singapore 835
Santa Clara 431
Hong Kong 406
Hefei 311
San Jose 247
Ashburn 172
Lauterbourg 153
Beijing 142
Seoul 142
Ho Chi Minh City 124
Los Angeles 105
Hanoi 81
Naples 70
Dallas 63
São Paulo 54
New York 47
Marigliano 34
Buffalo 31
Helsinki 26
Frankfurt am Main 23
Da Nang 22
Tokyo 22
Rome 21
Milan 19
Minamishinagawa 18
Rio de Janeiro 18
Montreal 15
Bengaluru 14
Düsseldorf 13
Johannesburg 13
Orem 13
Warsaw 13
Chicago 12
Denver 12
Haiphong 12
Hải Dương 12
Ninh Bình 12
Brooklyn 11
Atlanta 10
Belo Horizonte 10
Curitiba 10
Guayaquil 10
Toronto 10
Boardman 9
Council Bluffs 9
Mexico City 9
Phoenix 9
Chennai 8
Guarulhos 8
Manchester 8
Tashkent 8
Casoria 7
Charlotte 7
Dhaka 7
London 7
San Francisco 7
The Dalles 7
Amsterdam 6
Baghdad 6
Biên Hòa 6
Boston 6
Brasília 6
Dammam 6
Dublin 6
Falkenstein 6
Houston 6
Istanbul 6
Osasco 6
Philadelphia 6
Porto Alegre 6
Stockholm 6
Thái Nguyên 6
Ankara 5
Can Tho 5
Cape Town 5
Fortaleza 5
Goiânia 5
Jakarta 5
Kyiv 5
Lima 5
Mumbai 5
Nam Định 5
Piscataway 5
Poplar 5
Querétaro 5
Recife 5
Riyadh 5
Seattle 5
Shanghai 5
Sorocaba 5
Baku 4
Baltimore 4
Bauru 4
Bologna 4
Buenos Aires 4
Bắc Ninh 4
Campinas 4
Caserta 4
Ciudad del Este 4
Duque de Caxias 4
Totale 4.149
Nome #
Diabetes and Cognitive Impairment: A Role for Glucotoxicity and Dopaminergic Dysfunction 111
ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first-degree relatives of type 2 diabetics 96
Glucosamine-induced endoplasmic reticulum stress affects GLUT4 expression via activating transcription factor 6 in rat and human skeletal muscle cells. 94
Citrus aurantium L. Dry Extracts Ameliorate Adipocyte Differentiation of 3T3-L1 Cells Exposed to TNFα by Down-Regulating miR-155 Expression 92
The Relevance of Insulin Action in the Dopaminergic System 89
Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics 89
Cytotoxicity of dental resin composites: an in vitro evaluation. 84
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms. 82
Resveratrol Improves Endothelial Function by A PREP1-Mediated Pathway in Mouse Aortic Endothelial Cells 81
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic beta-cells. 80
Molecular basis of ageing in chronic metabolic diseases 79
Targetting PED/PEA-15 for diabetes treatment. 78
In severe obesity, subcutaneous adipose tissue cell-derived cytokines are early markers of impaired glucose tolerance and are modulated by quercetin 78
Thiazolidinediones control the expression of Ped/Pea-15 (phosphoprotein enriched in diabetes) both in vitro and in vivo 77
Adipocyte precursor cells from first degree relatives of type 2 diabetic patients feature changes in hsa-mir-23a-5p, -193a-5p, and -193b-5p and insulin-like growth factor 2 expression 76
A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice 76
Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner. 75
Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity 75
The Combination of Berberine, Tocotrienols and Coffee Extracts Improves Metabolic Profile and Liver Steatosis by the Modulation of Gut Microbiota and Hepatic miR-122 and miR-34a Expression in Mice 74
Glucose Enhances Pro-Tumorigenic Functions of Mammary Adipose-Derived Mesenchymal Stromal/Stem Cells on Breast Cancer Cell Lines 72
Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice 72
A peptide from the N-terminal region of PED/PEA-15 blocks its interaction with PLD1 and restores insulin sensitivity in skeletal muscle cells . 70
The Dual-Role of Methylglyoxal in Tumor Progression ??? Novel Therapeutic Approaches 69
DNA Methylation and Type 2 Diabetes: Novel Biomarkers for Risk Assessment? 68
Immunoglobulins G modulate endothelial function and affect insulin sensitivity in humans 68
Increased levels of versican and insulin-like growth factor 1 in peritumoral mammary adipose tissue are related to aggressiveness in estrogen receptor-positive breast cancer 67
Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects. 65
Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity 64
DNA methylation in cardiovascular disease and heart failure: novel prediction models? 64
Methylglyoxal Impairs the Pro-Angiogenic Ability of Mouse Adipose-Derived Stem Cells (mADSCs) via a Senescence-Associated Mechanism 64
PED gene overexpression impairs insulin action and secretion and glucose tolerance 63
GRP78 Mediates Cell Growth and Invasiveness in Endometrial Cancer 62
Hypomethylation at PANDAR promoter progressively induces senescence in adipocyte precursor cells in subjects with obesity and type 2 diabetes 61
Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage. 61
Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet 61
Altered PTPRD DNA Methylation Associates With Restricted Adipogenesis in Healthy First-Degree Relatives of Type 2 Diabetes Subjects 60
Chronic Adipose Tissue Inflammation Linking Obesity to Insulin Resistance and Type 2 Diabetes 60
Glyoxalase 1 knockdown induces age‐related β‐cell dysfunction and glucose intolerance in mice 60
The Pervasive Effects of ER Stress on a Typical Endocrine Cell: Dedifferentiation, Mesenchymal Shift and Antioxidant Response in the Thyrocyte 58
Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity 58
miR-214-dependent increase of PHLPP2 levels mediates the impairment of insulin-stimulated akt activation in mouse aortic endothelial cells exposed to methylglyoxal 57
Epigenetic Dysregulation of the Homeobox A5 (HOXA5) Gene Associates with Subcutaneous Adipocyte Hypertrophy in Human Obesity 57
Surgical stress and metabolic response after totally laparoscopic right colectomy 56
Increased hexosamine biosynthetic pathway flux dedifferentiates INS-1E cells and murine islets by an extracellular signal-regulated kinase (ERK)1/2-mediated signal transmission pathway. 56
Low-dose Bisphenol-A Promotes Epigenetic Changes at Pparγ Promoter in Adipose Precursor Cells 56
Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging 54
Adipose tissue dysfunction as determinant of obesity-associated metabolic complications 53
Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo. 52
The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells 52
Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes 52
PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1 52
Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5 52
KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2alpha 51
Citrus aurantium L. dry extracts promote C/ ebp? expression and improve adipocyte differentiation in 3T3-L1 cells 51
Mammary Adipose Tissue Control of Breast Cancer Progression: Impact of Obesity and Diabetes 51
The destiny of glucose from a MicroRNA perspective 49
Prep1 deficiency improves metabolic response in white adipose tissue 48
The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts. 48
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 47
Increased hexosamine biosynthetic pathway flux alters cell–cell adhesion in INS-1E cells and murine islets 47
Peroxisome proliferator-activated receptor-? activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1. 46
In L6 skeletal muscle cells, glucose induces cytosolic translocation of protein kinase C-alpha and trans-activates the insulin receptor kinase. 46
Prep1, A Homeodomain transcription factor involved in glucose and lipid metabolism 46
Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells 45
Understanding type 2 diabetes: from genetics to epigenetics 45
Adenoviral Gene Transfer of PLD1-D4 Enhances Insulin Sensitivity in Mice by Disrupting Phospholipase D1 Interaction with PED/PEA-15. 45
Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells 44
Potential Mechanisms of Bisphenol A (BPA) Contributing to Human Disease 44
L? insulina regola l? attivazione di PDK-1 (Phosphoinositides-Dependent Kinase-1) mediante fosforilazione in tirosina ed interazione con il recettore 43
Endoplasmic reticulum stress is activated in endometrial adenocarcinoma. 43
Nutritional factors, dna methylation, and risk of type 2 diabetes and obesity: Perspectives and challenges 43
Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 42
Role of the HIF-1?/Nur77 axis in the regulation of the tyrosine hydroxylase expression by insulin in PC12 cells 42
Selective disruption of insulin-like growth factor (IGF)-1 signalling via phosphoinositide-dependent kinase-1 prevents the protective effect of IGF-1 on human cancer cell death. 40
Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function. 39
PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice. 39
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development. 38
A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells 38
Human glycated albumin affects glucose metabolism in L6 skeletal muscle cells by impairing insulin-induced insulin receptor substrate (IRS) signaling through a protein kinase C alpha-mediated mechanism. 38
Adipocyte control of cancer cell growth 37
Lo stress del reticolo endoplasmatico (RE) indotto da glucosammina inibisce l'espressione del GLUT4 nelle cellule muscolari scheletriche mediante il fattore di attivazione della trascrizione (ATF) 6. 37
Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-² activity and TGF-²1 expression. 36
Trischitta V, Frittitta L. ENPP1 Affects Insulin Action and Secretion: Evidences from In Vitro Studies. 35
The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes. 35
Cell fate following ER stress: just a matter of "quo ante" recovery or death? 35
Molecular mechanisms controlling cancer cell growth: role of adipocyte-released factors 34
Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells. 34
Peptide antagonists of the PED-hPLD1 binding 33
An Extract, Transform, Load foundation for Biobank Data Interoperability 33
In Skeletal Muscle Advanced Glycation End Products (AGEs) Inhibit Insulin Action and Induce the Formation of Multimolecular Complexes Including the Receptor for AGEs 32
Platelet-Rich Plasma Increases Growth and Motility of Adipose Tissue-Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function 32
Omi/HtrA2 promotes cell death by binding and degrading the antiapoptotic protein PED/PEA-15. 32
Personalized medicine and type 2 diabetes: Lesson from epigenetics 32
Protein kinase Calpha activation by RET: evidence for a negative feedback mechanism controlling RET tyrosine kinase. 32
Thiazolidinediones control the expression of phosphoprotein enriched in diabetes (ped/pea-15) both in vitro and in vivo. 32
Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. 31
ENPP1 affects insulin action and secretion: evidences from in vitro studies. 31
The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism. 30
Prep1 regulates angiogenesis through a PGC-1?-mediated mechanism 30
IRS-1 and IRS-2 are recruited by TrkA receptor and oncogenic TRK-T1. 29
Totale 5.472
Categoria #
all - tutte 22.033
article - articoli 19.578
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.611


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/2024110 0 0 0 0 0 0 0 0 9 2 80 19
2024/20252.534 56 13 155 80 316 179 68 196 89 261 629 492
2025/20264.314 221 493 451 601 694 210 622 155 186 255 212 214
Totale 6.958