SPANU, PIETRO

SPANU, PIETRO  

Istituto di Chimica Biomolecolare - ICB - Sede Secondaria Sassari  

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Titolo Data di pubblicazione Autore(i) File
Design and synthesis of a new Non-Covalent Caspase-3 Inhibitor with Neuroprotective Property 1-gen-2023 Spanu, Pietro; Chandgudge, Ajay; Ulgheri, Fausta; Loriga, Giovanni; Fuggetta, MARIA PIA; M Dolga, Amalia; H Elsinga, Philip; Kopschina Feltes, Paula; J de Vries, Erik F; Domling, Alexander
Design, synthesis and biological evaluation of 1,5-disubstituted aamino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders 1-gen-2022 Ulgheri, Fausta; Spanu, Pietro; Deligia, Francesco; Loriga, Giovanni; Fuggetta, MARIA PIA; de Haan, Iris; Chandgudge, Ajay; Groves, Matthew; Domling, Alexander
Spectroscopic and in silico studies on the interaction of substituted pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one derivatives with c-myc g4-dna 1-gen-2021 Mulliri, S.; Laaksonen, A.; Spanu, P.; Farris, R.; Farci, M.; Mingoia, F.; Roviello, G.; Mocci, F.
Non-covalent inflammasome-caspase-1 complex inhibitors: New molecules targeting immune and inflammatory disorders including COVID-19 1-gen-2020 Ulgheri, Fausta; Spanu, Pietro; Deligia, Francesco; Loriga, Giovanni; Fuggetta, MARIA PIA; Morra, Andrea; de Haan, Iris; Chandgudge, Ajay; R Groves, Matthew; Domling, Alexander
"Green Chemistry" in "Drug Discovery": sintesi sostenibili di nuovi inibitori di telomerasi 1-gen-2019 De Luca, Lidia; Azzena, Ugo; Carraro, Massimo; Pinna, Luigi; Mocci, Francesca; ENGELBRECHT Leon De, Villiers; Spanu, Pietro; Gloria, Rassu; Marchetti, Mauro; Ulgheri, Fausta; Zambrano, Vincenzo
A new synthetic spiroketal: Studies on antitumor activity on murine melanoma model in vivo and mechanism of action in vitro 1-gen-2019 Fuggetta, Mp; Spanu, P; Ulgheri, F; Deligia, F; Carta, P; Mannu, A; Trotta, V; Cicco, Rd; Barra, A; Zona, E; Morelli, F
Novel therapeutic approach in a multiplicity of neurodegenerative and autoinflammatory pathologies 1-gen-2019 Spanu, Pietro; Ulgheri, Fausta; Loriga, Giovanni
Spectroscopic and in silico studies on the interaction of substituted-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one derivatives with c-myc and Tel22 1-gen-2019 G. Roviello ; S. Mulliri ; F. Mocci ; P. Spanu ; F. Mingoia
A New synthetic spiroketal: Antitumor Activity On Murine Melanoma Model In Vivo and MOA In Vitro 1-gen-2018 Spanu, Pietro; Fuggetta, MARIA PIA; Ulgheri, Fausta; Deligia, Francesco; Loriga, Giovanni; Carta, Paola; Mannu, Alberto; Trotta, Veronica; De Cicco, Rosanna; Barra, Adriano; Zona, Enrica; Morelli, Franco
An Efficient Chemical Conversion of Glycerol to Dihydroxyacetone 1-gen-2018 Ulgheri, Fausta; Spanu, Pietro
Caspasi, Miastenia Gravis e Distrofia Muscolare di duchenne 1-gen-2018 Spanu, Pietro; Doemling, Alexander; Deligia, Francesco; Fuggetta, MARIA PIA; Chandgude, Ajay; H Elsinga, Philip; Ulgheri, Fausta
Novel caspase inhibitors 1-gen-2018 Doemling, Alexander; Spanu, Pietro; Ulgheri, Fausta
2-hydroxy-8-methyl-1,7-dioxaspiro[5.5]undec-3-en-5-one: a Natural-Product-Inspired Spiroketal with in vivo Efficacy in Mouse Model of Melanoma 1-gen-2017 Spanu, Pietro; Pia Fuggetta, Maria; Ulgheri, Fausta; Carta, Paola; Deligia, Francesco; Zonfrillo, Manuela; Trotta, Veronica; De Cicco, Rosanna; Barra, Adriano; Zona, Enrica; Morelli, Franco
Potent Non-Covalent Inhibitors of Caspase-1 Targeting Neuroinflammation in Neurodegenerative Diseases 1-gen-2017 Fausta Ulgheri; Deligia F.; Fuggetta M.P.; Chandgude A. L.; Elsinga P.; de Vries E.F.J.; Doorduin J.; Kopschina Feltes P.; Dolga A.; Krabbendam I.; Dömling A. ; Spanu P.
Individuazione di Nuovi Lead per la Cura di Patologie Neurodegenerative 1-gen-2016 Spanu, Pietro; Ulgheri, Fausta; Ugo, Azzena; Luisa, Pisano; Francesca, Mocci
SYNTHESIS AND ENANTIOMERIC SEPARATION OF A NOVEL SPIROKETAL DERIVATIVE: A POTENT HUMAN TELOMERASE INHIBITOR WITH HIGH IN VITRO ANTICANCER ACTIVITY 1-gen-2016 Spanu, Pietro; DE MICO, Antonella; Cottarelli, Andrea; Morelli, Franco; Zonfrillo, Manuela; Ulgheri, Fausta; Peluso, Paola; Mannu, Alberto; Deligia, Francesco; Marchetti, Mauro; Roviello, Giovanni; Reyes Romero, Atilio; Domling, Alexander; Fuggetta, MARIA PIA
Synthesis and Enantiomeric Separation of a Novel Spiroketal Derivative: A Potent Human Telomerase Inhibitor with High in Vitro Anticancer Activity 1-gen-2016 Fuggetta, MARIA PIA; DE MICO, Antonella; Cottarelli, Andrea; Morelli, Franco; Zonfrillo, Manuela; Ulgheri, Fausta; Peluso, Paola; Mannu, Alberto; Deligia, Francesco; Marchetti, Mauro; Roviello, Giovanni; Romero Atilio, Reyes; Domling, Alexander; Spanu, Pietro
TARGETING NEUROINFLAMMATION THROUGH POTENT NON-COVALENT INHIBITORS OF CASPASE-1 1-gen-2016 Ulgheri, F; Deligia, F; Morra, A; Fuggetta, Mp; Chandgude, A L; Elsinga, P; de Vries, Efj; Doorduin, J; Kopschina Feltes, P; Dolga, A; Krabbendam, I; Spanu, P; Dömling, A
Potent non-covalent inhibitors of Caspase-1 1-gen-2015 L Chandgude, Ajay; Fuggetta, MARIA PIA; Meurs, Herman; Gosens, Reinoud; Groves, Matthew; Ulgheri, Fausta; Spanu, Pietro; Dömling, Alexander
An unexpected reaction of pyridine with acetyl chloride to give dihydropyridine and piperidine derivatives 1-gen-2014 Spanu P.; Mannu A.; Ulgheri F.