D'ADDA DI FAGAGNA, FABRIZIO
D'ADDA DI FAGAGNA, FABRIZIO
Istituto di Genetica Molecolare "Luigi Luca Cavalli Sforza"
CRISPR/Cas9 screens identify LIG1 as a sensitizer of PARP inhibitors in castration-resistant prostate cancer
2024 Fracassi, Giulia; Lorenzin, Francesca; Orlando, Francesco; Gioia, Ubaldo; D'Amato, Giacomo; Casaramona, Arnau S.; Cantore, Thomas; Prandi, Davide; Santer, Frédéric R.; Klocker, Helmut; d'Adda di Fagagna, Fabrizio; Mateo, Joaquin; Demichelis, Francesca
Guidelines for minimal information on cellular senescence experimentation in vivo
2024 Ogrodnik, Mikolaj; Carlos Acosta, Juan; Adams, Peter D.; d'Adda di Fagagna, Fabrizio; Baker, Darren J.; Bishop, Cleo L.; Chandra, Tamir; Collado, Manuel; Gil, Jesus; Gorgoulis, Vassilis; Gruber, Florian; Hara, Eiji; Jansen-Dürr, Pidder; Jurk, Diana; Khosla, Sundeep; Kirkland, James L.; Krizhanovsky, Valery; Minamino, Tohru; Niedernhofer, Laura J.; Passos, João F.; Ring, Nadja A. R.; Redl, Heinz; Robbins, Paul D.; Rodier, Francis; Scharffetter-Kochanek, Karin; Sedivy, John M.; Sikora, Ewa; Witwer, Kenneth; von Zglinicki, Thomas; Yun, Maximina H.; Grillari, Johannes; Demaria, Marco
Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
2023 Rosso, I; Jonesweinert, C; Rossiello, F; Cabrini, M; Brambillasca, S; Munozsagredo, L; Lavagnino, Z; Martini, E; Tedone, E; Garre', M; Aguado, J; Parazzoli, D; Mione, M; Shay, Jw; Mercurio, C; d'Adda di Fagagna, F
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT)
2023 Falcinelli, M; Dell'Omo, G; Grassi, E; Mariella, E; Leto, Sm; Scardellato, S; Lorenzato, A; Arena, S; Bertotti, A; Trusolino, L; Bardelli, A; d'Adda di Fagagna, F
SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence
2023 Gioia, U; Tavella, S; Martínezorellana, P; Cicio, G; Colliva, A; Ceccon, M; Cabrini, M; Henriques, Ac; Fumagalli, V; Paldino, A; Presot, E; Rajasekharan, S; Iacomino, N; Pisati, F; Matti, V; Sepe, S; Conte, Mi; Barozzi, S; Lavagnino, Z; Carletti, T; Volpe, Mc; Cavalcante, P; Iannacone, M; Rampazzo, C; Bussani, R; Tripodo, C; Zacchigna, S; Marcello, A; d'Adda di Fagagna, F
Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer
2023 Frittoli, E; Palamidessi, A; Iannelli, F; Zanardi, F; Villa, S; Barzaghi, L; Abdo, H; Cancila, V; Beznoussenko, Gv; Della Chiara, G; Pagani, M; Malinverno, C; Bhattacharya, D; Pisati, F; Yu, W; Galimberti, V; Bonizzi, G; Martini, E; Mironov, Aa; Gioia, U; Ascione, F; Li, Q; Havas, K; Magni, S; Lavagnino, Z; Pennacchio, Fa; Maiuri, P; Caponi, S; Mattarelli, M; Martino, S; d'Adda di Fagagna, F; Rossi, C; Lucioni, M; Tancredi, R; Pedrazzoli, P; Vecchione, A; Petrini, C; Ferrari, F; Lanzuolo, C; Bertalot, G; Nader, G; Foiani, M; Piel, M; Cerbino, R; Giavazzi, F; Tripodo, C; Scita, G
BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1
2022 Chen, D; Gervai, Jz; Poti, A; Nemeth, E; Szeltner, Z; Szikriszt, B; Gyure, Z; Zamborszky, J; Ceccon, M; d'Adda di Fagagna, F; Szallasi, Z; Richardson, Al; Szuts, D
DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging
2022 Sepe, S; Rossiello, F; Cancila, V; Iannelli, F; Matti, V; Cicio, G; Cabrini, M; Marinelli, E; Alabi, Br; di Lillo, A; Di Napoli, A; Shay, Jw; Tripodo, C; d'Adda di Fagagna, F
Telomere dysfunction in ageing and age-related diseases
2022 Rossiello, F; Jurk, D; Passos, Jf; d'Adda di Fagagna, F
TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance
2022 Buemi, Valentina; Schillaci, Odessa; Santorsola, Mariangela; Bonazza, Deborah; Broccia, Pamela Veneziano; Zappone, Annie; Bottin, Cristina; Dell'Omo, Giulia; Kengne, Sylvie; Cacchione, Stefano; Raffa, Grazia Daniela; Piazza, Silvano; d'Adda di Fagagna, Fabrizio; Benetti, Roberta; Cortale, Maurizio; Zanconati, Fabrizio; Del Sal, Giannino; Schoeftner, Stefan
A role for human dna polymerase λ in alternative lengthening of telomeres
2021 Mentegari, E.; Bertoletti, F.; Kissova, M.; Zucca, E.; Galli, S.; Tagliavini, G.; Garbelli, A.; Maffia, A.; Bione, S.; Ferrari, E.; d'Adda di Fagagna, F.; Francia, S.; Sabbioneda, S.; Chen, L. -Y.; Lingner, J.; Bergoglio, V.; Hoffmann, J. -S.; Hubscher, U.; Crespan, E.; Maga, G.
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2021 Di Micco, R; Krizhanovsky, V; Baker, D; d'Adda di Fagagna, F
DNA Damage Triggers a New Phase in Neurodegeneration
2021 Pessina, F; Gioia, U; Brandi, O; Farina, S; Ceccon, M; Francia, S; d'Adda di Fagagna, F
DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end-joining
2021 Cabrini, M; Roncador, M; Galbiati, A; Cipolla, L; Maffia, A; Iannelli, F; Sabbioneda, S; d'Adda di Fagagna, F; Francia, S
MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends
2021 Sharma, S; Anand, R; Zhang, X; Francia, S; Michelini, F; Galbiati, A; Williams, H; Ronato, Da; Masson, Jy; Rothenberg, E; Cejka, P; d'Adda di Fagagna, F
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury
2021 Uryga, Ak; Grootaert, Moj; Garrido, Am; Oc, S; Foote, K; Chappell, J; Finigan, A; Rossiello, F; d'Adda di Fagagna, F; Aravani, D; Jorgensen, Hf; Bennett, Mr
The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
2021 Napoletano, F; Ferrari Bravo, G; Voto, Iap; Santin, A; Celora, L; Campaner, E; Dezi, C; Bertossi, A; Valentino, E; Santorsola, M; Rustighi, A; Fajner, V; Maspero, E; Ansaloni, F; Cancila, V; Valenti, Cf; Santo, M; Artimagnella, Ob; Finaurini, S; Gioia, U; Polo, S; Sanges, R; Tripodo, C; Mallamaci, A; Gustincich, S; d'Adda di Fagagna, F; Mantovani, F; Specchia, V; Del Sal, G
Detection of Telomeric DNA:RNA Hybrids Using TeloDRIP-qPCR.
2020 Rosso, I; d'Adda di Fagagna, F
Telomere transcription in ageing
2020 Aguado, J; d'Adda di Fagagna, F; Wolvetang, E
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors
2019 Pessina, F; Giavazzi, F; Yin, Y; Gioia, U; Vitelli, V; Galbiati, A; Barozzi, S; Garre, M; Oldani, A; Flaus, A; Cerbino, R; Parazzoli, D; Rothenberg, E; d'Adda di Fagagna, F
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| CRISPR/Cas9 screens identify LIG1 as a sensitizer of PARP inhibitors in castration-resistant prostate cancer | 1-gen-2024 | Fracassi, Giulia; Lorenzin, Francesca; Orlando, Francesco; Gioia, Ubaldo; D'Amato, Giacomo; Casaramona, Arnau S.; Cantore, Thomas; Prandi, Davide; Santer, Frédéric R.; Klocker, Helmut; d'Adda di Fagagna, Fabrizio; Mateo, Joaquin; Demichelis, Francesca | |
| Guidelines for minimal information on cellular senescence experimentation in vivo | 1-gen-2024 | Ogrodnik, Mikolaj; Carlos Acosta, Juan; Adams, Peter D.; d'Adda di Fagagna, Fabrizio; Baker, Darren J.; Bishop, Cleo L.; Chandra, Tamir; Collado, Manuel; Gil, Jesus; Gorgoulis, Vassilis; Gruber, Florian; Hara, Eiji; Jansen-Dürr, Pidder; Jurk, Diana; Khosla, Sundeep; Kirkland, James L.; Krizhanovsky, Valery; Minamino, Tohru; Niedernhofer, Laura J.; Passos, João F.; Ring, Nadja A. R.; Redl, Heinz; Robbins, Paul D.; Rodier, Francis; Scharffetter-Kochanek, Karin; Sedivy, John M.; Sikora, Ewa; Witwer, Kenneth; von Zglinicki, Thomas; Yun, Maximina H.; Grillari, Johannes; Demaria, Marco | |
| Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs | 1-gen-2023 | Rosso, I; Jonesweinert, C; Rossiello, F; Cabrini, M; Brambillasca, S; Munozsagredo, L; Lavagnino, Z; Martini, E; Tedone, E; Garre', M; Aguado, J; Parazzoli, D; Mione, M; Shay, Jw; Mercurio, C; d'Adda di Fagagna, F | |
| Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT) | 1-gen-2023 | Falcinelli, M; Dell'Omo, G; Grassi, E; Mariella, E; Leto, Sm; Scardellato, S; Lorenzato, A; Arena, S; Bertotti, A; Trusolino, L; Bardelli, A; d'Adda di Fagagna, F | |
| SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence | 1-gen-2023 | Gioia, U; Tavella, S; Martínezorellana, P; Cicio, G; Colliva, A; Ceccon, M; Cabrini, M; Henriques, Ac; Fumagalli, V; Paldino, A; Presot, E; Rajasekharan, S; Iacomino, N; Pisati, F; Matti, V; Sepe, S; Conte, Mi; Barozzi, S; Lavagnino, Z; Carletti, T; Volpe, Mc; Cavalcante, P; Iannacone, M; Rampazzo, C; Bussani, R; Tripodo, C; Zacchigna, S; Marcello, A; d'Adda di Fagagna, F | |
| Tissue fluidification promotes a cGAS-STING cytosolic DNA response in invasive breast cancer | 1-gen-2023 | Frittoli, E; Palamidessi, A; Iannelli, F; Zanardi, F; Villa, S; Barzaghi, L; Abdo, H; Cancila, V; Beznoussenko, Gv; Della Chiara, G; Pagani, M; Malinverno, C; Bhattacharya, D; Pisati, F; Yu, W; Galimberti, V; Bonizzi, G; Martini, E; Mironov, Aa; Gioia, U; Ascione, F; Li, Q; Havas, K; Magni, S; Lavagnino, Z; Pennacchio, Fa; Maiuri, P; Caponi, S; Mattarelli, M; Martino, S; d'Adda di Fagagna, F; Rossi, C; Lucioni, M; Tancredi, R; Pedrazzoli, P; Vecchione, A; Petrini, C; Ferrari, F; Lanzuolo, C; Bertalot, G; Nader, G; Foiani, M; Piel, M; Cerbino, R; Giavazzi, F; Tripodo, C; Scita, G | |
| BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1 | 1-gen-2022 | Chen, D; Gervai, Jz; Poti, A; Nemeth, E; Szeltner, Z; Szikriszt, B; Gyure, Z; Zamborszky, J; Ceccon, M; d'Adda di Fagagna, F; Szallasi, Z; Richardson, Al; Szuts, D | |
| DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging | 1-gen-2022 | Sepe, S; Rossiello, F; Cancila, V; Iannelli, F; Matti, V; Cicio, G; Cabrini, M; Marinelli, E; Alabi, Br; di Lillo, A; Di Napoli, A; Shay, Jw; Tripodo, C; d'Adda di Fagagna, F | |
| Telomere dysfunction in ageing and age-related diseases | 1-gen-2022 | Rossiello, F; Jurk, D; Passos, Jf; d'Adda di Fagagna, F | |
| TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance | 1-gen-2022 | Buemi, Valentina; Schillaci, Odessa; Santorsola, Mariangela; Bonazza, Deborah; Broccia, Pamela Veneziano; Zappone, Annie; Bottin, Cristina; Dell'Omo, Giulia; Kengne, Sylvie; Cacchione, Stefano; Raffa, Grazia Daniela; Piazza, Silvano; d'Adda di Fagagna, Fabrizio; Benetti, Roberta; Cortale, Maurizio; Zanconati, Fabrizio; Del Sal, Giannino; Schoeftner, Stefan | |
| A role for human dna polymerase λ in alternative lengthening of telomeres | 1-gen-2021 | Mentegari, E.; Bertoletti, F.; Kissova, M.; Zucca, E.; Galli, S.; Tagliavini, G.; Garbelli, A.; Maffia, A.; Bione, S.; Ferrari, E.; d'Adda di Fagagna, F.; Francia, S.; Sabbioneda, S.; Chen, L. -Y.; Lingner, J.; Bergoglio, V.; Hoffmann, J. -S.; Hubscher, U.; Crespan, E.; Maga, G. | |
| Cellular senescence in ageing: from mechanisms to therapeutic opportunities | 1-gen-2021 | Di Micco, R; Krizhanovsky, V; Baker, D; d'Adda di Fagagna, F | |
| DNA Damage Triggers a New Phase in Neurodegeneration | 1-gen-2021 | Pessina, F; Gioia, U; Brandi, O; Farina, S; Ceccon, M; Francia, S; d'Adda di Fagagna, F | |
| DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end-joining | 1-gen-2021 | Cabrini, M; Roncador, M; Galbiati, A; Cipolla, L; Maffia, A; Iannelli, F; Sabbioneda, S; d'Adda di Fagagna, F; Francia, S | |
| MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends | 1-gen-2021 | Sharma, S; Anand, R; Zhang, X; Francia, S; Michelini, F; Galbiati, A; Williams, H; Ronato, Da; Masson, Jy; Rothenberg, E; Cejka, P; d'Adda di Fagagna, F | |
| Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury | 1-gen-2021 | Uryga, Ak; Grootaert, Moj; Garrido, Am; Oc, S; Foote, K; Chappell, J; Finigan, A; Rossiello, F; d'Adda di Fagagna, F; Aravani, D; Jorgensen, Hf; Bennett, Mr | |
| The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress | 1-gen-2021 | Napoletano, F; Ferrari Bravo, G; Voto, Iap; Santin, A; Celora, L; Campaner, E; Dezi, C; Bertossi, A; Valentino, E; Santorsola, M; Rustighi, A; Fajner, V; Maspero, E; Ansaloni, F; Cancila, V; Valenti, Cf; Santo, M; Artimagnella, Ob; Finaurini, S; Gioia, U; Polo, S; Sanges, R; Tripodo, C; Mallamaci, A; Gustincich, S; d'Adda di Fagagna, F; Mantovani, F; Specchia, V; Del Sal, G | |
| Detection of Telomeric DNA:RNA Hybrids Using TeloDRIP-qPCR. | 1-gen-2020 | Rosso, I; d'Adda di Fagagna, F | |
| Telomere transcription in ageing | 1-gen-2020 | Aguado, J; d'Adda di Fagagna, F; Wolvetang, E | |
| Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors | 1-gen-2019 | Pessina, F; Giavazzi, F; Yin, Y; Gioia, U; Vitelli, V; Galbiati, A; Barozzi, S; Garre, M; Oldani, A; Flaus, A; Cerbino, R; Parazzoli, D; Rothenberg, E; d'Adda di Fagagna, F |