MORETTI, FABIOLA
MORETTI, FABIOLA
Istituto di Biochimica e Biologia Cellulare - IBBC - Sede Secondaria Monterotondo
Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment
2025 Sardina, Francesca; Polverino, Federica; Valentini, Sonia; Carsetti, Claudia; Falvo, Elisabetta; Tisci, Giada; Soddu, Silvia; Moretti, Fabiola; Paiardini, Alessandro; Rinaldo, Cinzia
Targeting the MDM2-MDM4 interaction interface reveals an otherwise therapeutically active wild-type p53 in colorectal cancer
2025 Valentini, Sonia; Mele, Giada; Attili, Marika; Assenza, Maria Rita; Saccoccia, Fulvio; Sardina, Francesca; Rinaldo, Cinzia; Massari, Roberto; Tirelli, Nicola; Pontecorvi, Alfredo; Moretti, Fabiola
Rational design, synthesis, and biophysical characterization of a peptidic MDM2-MDM4 interaction inhibitor
2024 Ballarotto, Marco; Bianconi, Elisa; Valentini, Sonia; Temperini, Andrea; Moretti, Fabiola; Macchiarulo, Antonio
Early Social Enrichment Modulates Tumor Progression and p53 Expression in Adult Mice
2022 Middei, S; Giorgini, L; Vacca, V; Storri, F; Putti, S; Strimpakos, G; Raspa, M; Scavizzi, F; Moretti, F; D'Amato, Fr
HIPK2 cooperates with KRAS signaling and associates with colorectal cancer progression
2022 Di Segni, M; Virdia, I; Verdina, A; Amoreo, C; Baldari, S; Toietta, G; Diodoro, Mg; Mottolese, M; Sperduti, I; Moretti, F; Buglioni, S; Soddu, S; Di Rocco, G
In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles
2021 Maiullari, F; Chirivi, M; Costantini, M; Ferretti, Am; Recchia, S; Maiullari, S; Milan, M; Presutti, D; Pace, V; Raspa, M; Scavizzi, F; Massetti, M; Petrella, L; Fanelli, M; Rizzi, M; Fortunato, O; Moretti, F; Caradonna, E; Bearzi, C; Rizzi, R
Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties
2021 Lucà, Rossella; Assenza, MARIA RITA; Maiullari, Fabio; Pieroni, Luisa; Maiullari, Silvia; Federici, Giulia; Marini, Federica; Rizzi, Roberto; Urbani, Andrea; Soddu, Silvia; Moretti, Fabiola
p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity
2021 Arena, A.; Stigliano, A.; Belcastro, E.; Giorda, E.; Rosado, M. M.; Grossi, A.; Assenza, M. R.; Moretti, F.; Fierabracci, A.
Role of Sex in the Therapeutic Targeting of p53 Circuitry
2021 Mancini, F.; Giorgini, L.; Teveroni, E.; Pontecorvi, A.; Moretti, F.
Concentration of Metals and Trace Elements in the Normal Human and Rat Thyroid: Comparison with Muscle and Adipose Tissue and Volcanic Versus Control Areas
2020 Malandrino, Pasqualino; Russo, Marco; Ronchi, Anna; Moretti, Fabiola; Giani, Fiorenza; Vigneri, Paolo; Masucci, Romilda; Pellegriti, Gabriella; Belfiore, Antonino; Vigneri, Riccardo
Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients
2020 Pellegrino, M.; Traversi, G.; Arena, A.; Cappa, M.; Rosado, M. M.; Andreani, M.; Delfino, D. V.; Moretti, F.; Fierabracci, A.
Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells
2020 Caggiano, Cinzia; Guida, Eugenia; Todaro, Federica; Bielli, Pamela; Mori, Mattia; Ghirga, Francesca; Quaglio, Deborah; Botta, Bruno; Moretti, Fabiola; Grimaldi, Paola; Rossi, Pellegrino; Jannini Emmanuele, A; Barchi, Marco; Dolci, Susanna
Estrogens counteract platinum-chemosensitivity by modifying the subcellular localization of MDM4
2019 Lucà, Rossella; Blasio Giorgia, Di; Gallo, Daniela; Monteleone, Valentina; Manni, Isabella; Fici, Laura; Buttarelli, Marianna; Ciolli, Germana; Pellegrino, Marsha; Teveroni, Emanuela; Maiullari, Silvia; Ciucci, Alessandra; Apollo, Alessandro; Mancini, Francesca; Gentileschi Maria, Pia; Zannoni Gian, Franco; Pontecorvi, Alfredo; Scambia, Giovanni; Moretti, Fabiola
Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents
2017 Canu, Nadia; Pagano, Ilaria; La Rosa, Luca Rosario; Pellegrino, Marsha; Ciotti, MARIA TERESA; Mercanti, Delio; Moretti, Fabiola; Sposato, Valentina; Triaca, Viviana; Petrella, Carla; Maruyama Ichiro, N; Levi, Andrea; Calissano, Pietro
Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.
2017 Teveroni, Emanuela; Pellegrino, Marsha; Sacconi, Sabrina; Calandra, Patrizia; Cascino, Isabella; Fariolivecchioli, Stefano; Puma, Angela; Garibaldi, Matteo; Morosetti, Roberta; Tasca, Giorgio; Ricci, Enzo; Trevisan Carlo, Pietro; Galluzzi, Giuliana; Pontecorvi, Alfredo; Crescenzi, Marco; Deidda, Giancarlo; Moretti, Fabiola
Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation
2017 Luca, E; Fici, L; Ronchi, A; Marandino, F; Rossi, Ed; Caristo, Me; Malandrino, P; Russo, M; Pontecorvi, A; Vigneri, R; Moretti, F
MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.
2017 Mancini, Francesca; Teveroni, Emanuela; Di Conza, Giusy; Monteleone, Valentina; Arisi, Ivan; Pellegrino, Marsha; Buttarelli, Marianna; Pieroni, Luisa; D'Onofrio, Mara; Urbani, Andrea; Pontecorvi, Alfredo; Mazzone, Massimiliano; Moretti, Fabiola
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1alpha Levels and Colorectal Cancer Cell Survival under Hypoxia.
2017 Di Conza, Giusy; Trusso Cafarello, Sarah; Loroch, Stefan; Mennerich, Daniela; Deschoemaeker, Sofie; Di Matteo, Mario; Ehling, Manuel; Gevaert, Kris; Prenen, Hans; Zahedi Rene, Peiman; Sickmann, Albert; Kietzmann, Thomas; Moretti, Fabiola; Mazzone, Massimiliano
Allele-specific DNA hypomethylation characterises FSHD1 and FSHD2
2016 Calandra, P; Cascino, I; Lemmers, Rj; Galluzzi, G; Teveroni, E; Monforte, M; Tasca, G; Ricci, E; Moretti, F; van der Maarel, Sm; Deidda, G
MDM2-MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance
2016 Moscetti, Ilaria; Teveroni, Emanuela; Moretti, Fabiola; Bizzarri Anna, Rita; Cannistraro, Salvatore
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment | 1-gen-2025 | Sardina, Francesca; Polverino, Federica; Valentini, Sonia; Carsetti, Claudia; Falvo, Elisabetta; Tisci, Giada; Soddu, Silvia; Moretti, Fabiola; Paiardini, Alessandro; Rinaldo, Cinzia | |
| Targeting the MDM2-MDM4 interaction interface reveals an otherwise therapeutically active wild-type p53 in colorectal cancer | 1-gen-2025 | Valentini, Sonia; Mele, Giada; Attili, Marika; Assenza, Maria Rita; Saccoccia, Fulvio; Sardina, Francesca; Rinaldo, Cinzia; Massari, Roberto; Tirelli, Nicola; Pontecorvi, Alfredo; Moretti, Fabiola | |
| Rational design, synthesis, and biophysical characterization of a peptidic MDM2-MDM4 interaction inhibitor | 1-gen-2024 | Ballarotto, Marco; Bianconi, Elisa; Valentini, Sonia; Temperini, Andrea; Moretti, Fabiola; Macchiarulo, Antonio | |
| Early Social Enrichment Modulates Tumor Progression and p53 Expression in Adult Mice | 1-gen-2022 | Middei, S; Giorgini, L; Vacca, V; Storri, F; Putti, S; Strimpakos, G; Raspa, M; Scavizzi, F; Moretti, F; D'Amato, Fr | |
| HIPK2 cooperates with KRAS signaling and associates with colorectal cancer progression | 1-gen-2022 | Di Segni, M; Virdia, I; Verdina, A; Amoreo, C; Baldari, S; Toietta, G; Diodoro, Mg; Mottolese, M; Sperduti, I; Moretti, F; Buglioni, S; Soddu, S; Di Rocco, G | |
| In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles | 1-gen-2021 | Maiullari, F; Chirivi, M; Costantini, M; Ferretti, Am; Recchia, S; Maiullari, S; Milan, M; Presutti, D; Pace, V; Raspa, M; Scavizzi, F; Massetti, M; Petrella, L; Fanelli, M; Rizzi, M; Fortunato, O; Moretti, F; Caradonna, E; Bearzi, C; Rizzi, R | |
| Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties | 1-gen-2021 | Lucà, Rossella; Assenza, MARIA RITA; Maiullari, Fabio; Pieroni, Luisa; Maiullari, Silvia; Federici, Giulia; Marini, Federica; Rizzi, Roberto; Urbani, Andrea; Soddu, Silvia; Moretti, Fabiola | |
| p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity | 1-gen-2021 | Arena, A.; Stigliano, A.; Belcastro, E.; Giorda, E.; Rosado, M. M.; Grossi, A.; Assenza, M. R.; Moretti, F.; Fierabracci, A. | |
| Role of Sex in the Therapeutic Targeting of p53 Circuitry | 1-gen-2021 | Mancini, F.; Giorgini, L.; Teveroni, E.; Pontecorvi, A.; Moretti, F. | |
| Concentration of Metals and Trace Elements in the Normal Human and Rat Thyroid: Comparison with Muscle and Adipose Tissue and Volcanic Versus Control Areas | 1-gen-2020 | Malandrino, Pasqualino; Russo, Marco; Ronchi, Anna; Moretti, Fabiola; Giani, Fiorenza; Vigneri, Paolo; Masucci, Romilda; Pellegriti, Gabriella; Belfiore, Antonino; Vigneri, Riccardo | |
| Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients | 1-gen-2020 | Pellegrino, M.; Traversi, G.; Arena, A.; Cappa, M.; Rosado, M. M.; Andreani, M.; Delfino, D. V.; Moretti, F.; Fierabracci, A. | |
| Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells | 1-gen-2020 | Caggiano, Cinzia; Guida, Eugenia; Todaro, Federica; Bielli, Pamela; Mori, Mattia; Ghirga, Francesca; Quaglio, Deborah; Botta, Bruno; Moretti, Fabiola; Grimaldi, Paola; Rossi, Pellegrino; Jannini Emmanuele, A; Barchi, Marco; Dolci, Susanna | |
| Estrogens counteract platinum-chemosensitivity by modifying the subcellular localization of MDM4 | 1-gen-2019 | Lucà, Rossella; Blasio Giorgia, Di; Gallo, Daniela; Monteleone, Valentina; Manni, Isabella; Fici, Laura; Buttarelli, Marianna; Ciolli, Germana; Pellegrino, Marsha; Teveroni, Emanuela; Maiullari, Silvia; Ciucci, Alessandra; Apollo, Alessandro; Mancini, Francesca; Gentileschi Maria, Pia; Zannoni Gian, Franco; Pontecorvi, Alfredo; Scambia, Giovanni; Moretti, Fabiola | |
| Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents | 1-gen-2017 | Canu, Nadia; Pagano, Ilaria; La Rosa, Luca Rosario; Pellegrino, Marsha; Ciotti, MARIA TERESA; Mercanti, Delio; Moretti, Fabiola; Sposato, Valentina; Triaca, Viviana; Petrella, Carla; Maruyama Ichiro, N; Levi, Andrea; Calissano, Pietro | |
| Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity. | 1-gen-2017 | Teveroni, Emanuela; Pellegrino, Marsha; Sacconi, Sabrina; Calandra, Patrizia; Cascino, Isabella; Fariolivecchioli, Stefano; Puma, Angela; Garibaldi, Matteo; Morosetti, Roberta; Tasca, Giorgio; Ricci, Enzo; Trevisan Carlo, Pietro; Galluzzi, Giuliana; Pontecorvi, Alfredo; Crescenzi, Marco; Deidda, Giancarlo; Moretti, Fabiola | |
| Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation | 1-gen-2017 | Luca, E; Fici, L; Ronchi, A; Marandino, F; Rossi, Ed; Caristo, Me; Malandrino, P; Russo, M; Pontecorvi, A; Vigneri, R; Moretti, F | |
| MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability. | 1-gen-2017 | Mancini, Francesca; Teveroni, Emanuela; Di Conza, Giusy; Monteleone, Valentina; Arisi, Ivan; Pellegrino, Marsha; Buttarelli, Marianna; Pieroni, Luisa; D'Onofrio, Mara; Urbani, Andrea; Pontecorvi, Alfredo; Mazzone, Massimiliano; Moretti, Fabiola | |
| The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1alpha Levels and Colorectal Cancer Cell Survival under Hypoxia. | 1-gen-2017 | Di Conza, Giusy; Trusso Cafarello, Sarah; Loroch, Stefan; Mennerich, Daniela; Deschoemaeker, Sofie; Di Matteo, Mario; Ehling, Manuel; Gevaert, Kris; Prenen, Hans; Zahedi Rene, Peiman; Sickmann, Albert; Kietzmann, Thomas; Moretti, Fabiola; Mazzone, Massimiliano | |
| Allele-specific DNA hypomethylation characterises FSHD1 and FSHD2 | 1-gen-2016 | Calandra, P; Cascino, I; Lemmers, Rj; Galluzzi, G; Teveroni, E; Monforte, M; Tasca, G; Ricci, E; Moretti, F; van der Maarel, Sm; Deidda, G | |
| MDM2-MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance | 1-gen-2016 | Moscetti, Ilaria; Teveroni, Emanuela; Moretti, Fabiola; Bizzarri Anna, Rita; Cannistraro, Salvatore |