RIZZUTI, BRUNO
 Distribuzione geografica
Continente #
AS - Asia 1.909
NA - Nord America 1.117
EU - Europa 459
SA - Sud America 359
AF - Africa 35
OC - Oceania 3
Totale 3.882
Nazione #
US - Stati Uniti d'America 1.074
SG - Singapore 807
CN - Cina 407
BR - Brasile 287
VN - Vietnam 222
HK - Hong Kong 209
FR - Francia 143
IT - Italia 124
KR - Corea 60
FI - Finlandia 46
IN - India 39
NL - Olanda 36
JP - Giappone 32
GB - Regno Unito 29
DE - Germania 28
AR - Argentina 26
BD - Bangladesh 24
CA - Canada 16
IQ - Iraq 16
ZA - Sudafrica 15
EC - Ecuador 14
ID - Indonesia 13
TR - Turchia 13
IL - Israele 12
MX - Messico 9
UZ - Uzbekistan 9
CL - Cile 8
CO - Colombia 7
PK - Pakistan 7
IE - Irlanda 6
RU - Federazione Russa 6
UA - Ucraina 6
VE - Venezuela 6
AT - Austria 5
AE - Emirati Arabi Uniti 4
EG - Egitto 4
JO - Giordania 4
NP - Nepal 4
PH - Filippine 4
PT - Portogallo 4
PY - Paraguay 4
AO - Angola 3
AZ - Azerbaigian 3
BH - Bahrain 3
CH - Svizzera 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
ES - Italia 3
GT - Guatemala 3
HU - Ungheria 3
PA - Panama 3
PE - Perù 3
PL - Polonia 3
SA - Arabia Saudita 3
SE - Svezia 3
AL - Albania 2
AU - Australia 2
BB - Barbados 2
BO - Bolivia 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
ET - Etiopia 2
JM - Giamaica 2
KZ - Kazakistan 2
MY - Malesia 2
OM - Oman 2
PS - Palestinian Territory 2
QA - Qatar 2
UY - Uruguay 2
BA - Bosnia-Erzegovina 1
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
CY - Cipro 1
GA - Gabon 1
IR - Iran 1
IS - Islanda 1
KE - Kenya 1
KW - Kuwait 1
LT - Lituania 1
MA - Marocco 1
MN - Mongolia 1
MU - Mauritius 1
NC - Nuova Caledonia 1
NO - Norvegia 1
RO - Romania 1
RS - Serbia 1
SI - Slovenia 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
TZ - Tanzania 1
Totale 3.882
Città #
Santa Clara 498
Singapore 445
Hong Kong 207
Hefei 139
Lauterbourg 100
San Jose 98
Ho Chi Minh City 73
Beijing 68
Los Angeles 61
Seoul 60
Hanoi 54
Council Bluffs 51
Ashburn 48
Lappeenranta 25
São Paulo 20
Helsinki 19
New York 19
Dallas 18
Florence 17
Haiphong 15
Da Nang 14
Rende 14
Frankfurt am Main 13
Rome 13
Tokyo 13
Mumbai 10
Belo Horizonte 9
Genoa 8
Naples 8
Orem 8
Rio de Janeiro 8
Tashkent 8
Baghdad 7
Chennai 7
Denver 7
Minamishinagawa 7
Biên Hòa 6
Boston 6
Buffalo 6
Nuremberg 6
Osaka 6
Atlanta 5
Brooklyn 5
Cape Town 5
Cittanova 5
Curitiba 5
Dublin 5
Falkenstein 5
Guayaquil 5
Montreal 5
Phoenix 5
Poplar 5
Porto Alegre 5
Quito 5
Amman 4
Campinas 4
Catania 4
Jakarta 4
Johannesburg 4
Maceió 4
Marseille 4
Santiago 4
Belém 3
Bexley 3
Cabo Frio 3
Columbus 3
Düsseldorf 3
Elk Grove Village 3
Foshan 3
Guarulhos 3
Hamad Town 3
Hortolândia 3
Hải Dương 3
Imperatriz 3
Joinville 3
Luanda 3
Manchester 3
Nanjing 3
Newark 3
Nha Trang 3
Panama City 3
Paris 3
Philadelphia 3
Phủ Lý 3
Portsmouth 3
Roubaix 3
Sacramento 3
Santa Fe 3
Santo André 3
Shanghai 3
Sorocaba 3
São José dos Campos 3
São José dos Pinhais 3
Thái Bình 3
Turin 3
Vienna 3
Vinh 3
Vitória da Conquista 3
Addis Ababa 2
Albuquerque 2
Totale 2.428
Nome #
Dissecting CYP1A2 activation by arylalkanoic acid prodrugs toward the development of anti-inflammatory agents 117
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 102
The C terminus of the ribosomal-associated protein LrtA is an intrinsically disordered oligomer 94
Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation 93
Deciphering the binding of the nuclear localization sequence of Myc protein to the nuclear carrier Importin α3 74
Virtual screening in drug discovery: a precious tool for a still-demanding challenge 68
Early stage aggregation of human serum albumin in the presence of metal ions 62
Thermal liquid biopsy (TLB) of blood plasma as a potential tool to help in the early diagnosis of multiple sclerosis 62
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 60
Anionic versus neutral Pt(II) complexes: The relevance of the charge for human serum albumin binding 58
The interaction of tryptophan enantiomers with model membranes is modulated by polar head type and physical state of phospholipids 57
Biochemical and biophysical characterization of PADI4 supports its involvement in cancer 56
Promising perspectives of the antiproliferative GPER inverse agonist ERα17p in breast cancer 56
Erratum to “Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation” [Biophysical Chemistry …(2024) …] 55
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation 55
Intrinsically Disordered Chromatin Protein NUPR1 Binds to the Enzyme PADI4 55
Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity 55
Conformational stability of the N-terminal region of MDM2 55
Human enzyme PADI4 binds to the nuclear carrier Importin α3 54
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability 53
Polyphenols from citrus Tacle® extract endowed with HMGCR inhibitory activity: an antihypercholesterolemia natural remedy 52
Ecofriendly aminochalcogenation of alkenes: a green alternative to obtain compounds with potential anti-SARS-CoV-2 activity 52
New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4 50
Stereoselective and domain-specific effects of ibuprofen on the thermal stability of human serum albumin 50
New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides 49
The intrinsically disordered, epigenetic factor RYBP binds to the citrullinating enzyme PADI4 in cancer cells 48
Catalytic activity of copper ions in the amyloid fibrillation of beta-lactoglobulin 47
Design of inhibitors of the intrinsically disordered protein NUPR1: balance between drug affinity and target function 47
Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations 46
Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation 46
The armadillo-repeat domain of Plakophilin 1 binds to human enzyme PADI4 46
Development of an efficient NUPR1 inhibitor with anticancer activity 45
The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect 45
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 45
Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells 45
Targeting intrinsically disordered proteins involved in cancer 44
Computational approaches for the discovery of GPER targeting compounds 44
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B 43
Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs 43
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 43
Unveiling the binding between the armadillo-repeat domain of Plakophilin 1 and the intrinsically disordered transcriptional repressor RYBP 43
Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site 43
Effects of polar head nature and tail length of single-chain lipids on the conformational stability of β-lactoglobulin 42
The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3 42
Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation 42
Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1) 41
A phosphorylation-induced switch in the nuclear localization sequence of the intrinsically disordered NUPR1 hampers binding to importin 40
Association of ibuprofen at the polar/apolar interface of lipid membranes 39
Molecular dynamics of amicyanin reveals a conserved dynamical core for blue copper proteins 39
The peptide ERα17p is a GPER inverse agonist that exerts antiproliferative effects in breast cancer cells 39
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 39
Resveratrol induces chain interdigitation in DPPC cell membrane model systems 39
The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered 38
Identification by molecular docking of homoisoflavones from Leopoldia comosa as ligands of estrogen receptors 38
Dynamics and unfolding pathway of chimeric azurin variants: insights from molecular dynamics simulation 38
I° Mercato delle Attività di Ricerca, ITA-Innovazione Tecnologica Applicata, 20 Dic 2005, 15-18 Mazo 2006 38
Binding of warfarin differently affects the thermal behavior and chain packing of anionic, zwitterionic and cationic lipid membranes 37
Targeting the stress-induced protein NUPR1 to treat pancreatic adenocarcinoma 37
Seleno-functionalization of quercetin improves the non-covalent inhibition of Mpro and its antiviral activity in cells against SARS-CoV-2 37
Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1 37
Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solution 36
Ferric ions inhibit the amyloid fibrillation of β-lactoglobulin at high temperature 36
Resveratrol induces thermal stabilization of human serum albumin and modulates the early aggregation stage 36
The role of Lys525 on the head-group anchoring of fatty acids in the highest affinity binding site of albumin 36
The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue 35
Determinants of the pKa values of ionizable residues in an intrinsically disordered protein 35
Stability of trans-resveratrol associated with transport proteins 35
Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin α 35
Using simulations to provide the framework for experimental protein folding studies 35
Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis 34
Evidence of reduced flexibility in disulfide bridge-depleted azurin: a molecular dynamics simulation study 34
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 33
Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values 33
Residual helicity at the active site of the histidine phosphocarrier, HPr, modulates binding affinity to its natural partners 33
Dendrimers as competitors of protein-protein interactions of the intrinsically disordered nuclear chromatin protein NUPR1 33
Nanomedicines meet disordered proteins: A shift from traditional materials and concepts to innovative polymers 32
Sub-micromolar inhibition of SARS-CoV-2 3CLpro by natural compounds 32
Molecular simulations of proteins: From simplified physical interactions to complex biological phenomena 32
Toward multitasking pharmacological COX-targeting agents: Non-steroidal anti-inflammatory prodrugs with antiproliferative effects 32
Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites 32
Early stage aggregation of human serum albumin in the presence of metal ions 32
The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73 32
ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents 32
Active site modeling in copper azurin molecular dynamics simulations 32
The early steps in the unfolding of azurin 31
Thermally induced denaturation and aggregation of BLG-A: effect of the Cu2+ and Zn2+ metal ions 31
Human COA3 Is an Oligomeric Highly Flexible Protein in Solution 30
Structural, dynamical and functional aspects of the inner motions in the blue copper protein azurin 30
Dynamics of the intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner 30
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 30
Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening 30
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 30
The paralogue of the intrinsically disordered nuclear protein 1 has a nuclear localization sequence that binds to human importin α3 29
Coordination and dynamics of fatty acids in the highest-affinity binding site of human serum albumin 29
Dynamics and binding affinity of spin-labelled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation 27
The cyanobacterial ribosomal-associated protein LrtA from Synechocystis sp. PCC 6803 is an oligomeric protein in solution with chameleonic sequence properties 27
Identification of a drug targeting an intrinsically disordered protein involved in pancreatic adenocarcinoma 27
Crowding effects on the structure and dynamics of the intrinsically disordered nuclear chromatin protein NUPR1 27
Fatty acid association/dissociation in human serum albumin 26
Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm 26
Totale 4.326
Categoria #
all - tutte 15.177
article - articoli 14.272
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 149
Totale 29.598


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 23 0 3 3
2024/20252.115 5 7 108 55 483 99 271 314 40 79 320 334
2025/20262.324 86 163 242 413 401 133 380 119 151 152 84 0
Totale 4.468