RIZZUTI, BRUNO
 Distribuzione geografica
Continente #
AS - Asia 1.992
NA - Nord America 1.670
Continente sconosciuto - Info sul continente non disponibili 586
EU - Europa 554
SA - Sud America 401
AF - Africa 37
OC - Oceania 3
Totale 5.243
Nazione #
US - Stati Uniti d'America 1.596
SG - Singapore 811
CN - Cina 409
BR - Brasile 301
VN - Vietnam 228
HK - Hong Kong 210
IT - Italia 201
FR - Francia 144
BD - Bangladesh 69
KR - Corea 60
FI - Finlandia 46
IN - India 41
NL - Olanda 38
GB - Regno Unito 35
JP - Giappone 33
CA - Canada 31
AR - Argentina 29
DE - Germania 29
EC - Ecuador 21
CO - Colombia 20
ID - Indonesia 17
IQ - Iraq 16
ZA - Sudafrica 15
IL - Israele 13
TR - Turchia 13
MX - Messico 11
UZ - Uzbekistan 9
VE - Venezuela 9
CL - Cile 8
PH - Filippine 8
MY - Malesia 7
PK - Pakistan 7
IE - Irlanda 6
JM - Giamaica 6
RU - Federazione Russa 6
SA - Arabia Saudita 6
UA - Ucraina 6
AE - Emirati Arabi Uniti 5
AT - Austria 5
DO - Repubblica Dominicana 5
PY - Paraguay 5
CR - Costa Rica 4
EG - Egitto 4
ES - Italia 4
GT - Guatemala 4
JO - Giordania 4
NP - Nepal 4
PT - Portogallo 4
AO - Angola 3
AZ - Azerbaigian 3
BH - Bahrain 3
BO - Bolivia 3
CH - Svizzera 3
HU - Ungheria 3
PA - Panama 3
PE - Perù 3
PL - Polonia 3
PS - Palestinian Territory 3
SE - Svezia 3
AL - Albania 2
AU - Australia 2
BA - Bosnia-Erzegovina 2
BB - Barbados 2
CZ - Repubblica Ceca 2
DZ - Algeria 2
ET - Etiopia 2
HN - Honduras 2
KZ - Kazakistan 2
MA - Marocco 2
NO - Norvegia 2
OM - Oman 2
QA - Qatar 2
RS - Serbia 2
TH - Thailandia 2
UY - Uruguay 2
BJ - Benin 1
BS - Bahamas 1
BW - Botswana 1
BZ - Belize 1
CD - Congo 1
CY - Cipro 1
EE - Estonia 1
GA - Gabon 1
GP - Guadalupe 1
GR - Grecia 1
IR - Iran 1
IS - Islanda 1
KE - Kenya 1
KG - Kirghizistan 1
KW - Kuwait 1
LT - Lituania 1
LY - Libia 1
MD - Moldavia 1
MN - Mongolia 1
MT - Malta 1
MU - Mauritius 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
PR - Porto Rico 1
RO - Romania 1
Totale 4.653
Città #
Santa Clara 501
Singapore 448
Hong Kong 208
San Jose 170
Hefei 139
Ashburn 115
Lauterbourg 100
Ho Chi Minh City 75
Beijing 69
Los Angeles 68
Seoul 60
Council Bluffs 57
Hanoi 56
Lappeenranta 25
Dallas 23
New York 22
Rome 21
São Paulo 20
Helsinki 19
Milan 19
Florence 17
Da Nang 15
Haiphong 15
Rende 14
Tokyo 14
Frankfurt am Main 13
Naples 13
Phoenix 11
Mumbai 10
Belo Horizonte 9
Denver 9
Houston 9
Quito 9
Brooklyn 8
Buffalo 8
Genoa 8
Guayaquil 8
Orem 8
Philadelphia 8
Rio de Janeiro 8
Tashkent 8
Atlanta 7
Baghdad 7
Boston 7
Chennai 7
Minamishinagawa 7
Toronto 7
Biên Hòa 6
Chicago 6
Montreal 6
Newark 6
Nuremberg 6
Osaka 6
Brasília 5
Cape Town 5
Catania 5
Cittanova 5
Curitiba 5
Dublin 5
Falkenstein 5
Figino 5
Jacksonville 5
Las Vegas 5
Medellín 5
Poplar 5
Porto Alegre 5
Turin 5
Amman 4
Campinas 4
Jakarta 4
Johannesburg 4
Joinville 4
Kingston 4
Maceió 4
Marseille 4
Miami 4
Milwaukee 4
Paris 4
Sacramento 4
Santiago 4
Washington 4
Belém 3
Bexley 3
Cabo Frio 3
Chesapeake 3
Clinton Township 3
Columbus 3
Detroit 3
Dhaka 3
Düsseldorf 3
Elk Grove Village 3
Foshan 3
Guarulhos 3
Hamad Town 3
Hortolândia 3
Hải Dương 3
Imperatriz 3
Kuala Lumpur 3
Luanda 3
Manchester 3
Totale 2.698
Nome #
Dissecting CYP1A2 activation by arylalkanoic acid prodrugs toward the development of anti-inflammatory agents 137
Interaction of letrozole and its degradation products with aromatase: chemometric assessment of kinetics and structure-based binding validation 126
The G Protein Estrogen Receptor (GPER) is involved in the resistance to the CDK4/6 inhibitor palbociclib in breast cancer 109
Intrinsically Disordered Chromatin Protein NUPR1 Binds to the Enzyme PADI4 103
The C terminus of the ribosomal-associated protein LrtA is an intrinsically disordered oligomer 101
AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs) 87
Deciphering the binding of the nuclear localization sequence of Myc protein to the nuclear carrier Importin α3 81
Biochemical and biophysical characterization of PADI4 supports its involvement in cancer 74
Early stage aggregation of human serum albumin in the presence of metal ions 71
Virtual screening in drug discovery: a precious tool for a still-demanding challenge 71
Thermal liquid biopsy (TLB) of blood plasma as a potential tool to help in the early diagnosis of multiple sclerosis 69
Erratum to “Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation” [Biophysical Chemistry …(2024) …] 65
Targeting of mitochondrial fission through natural flavanones elicits anti-myeloma activity 65
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation 64
The interaction of tryptophan enantiomers with model membranes is modulated by polar head type and physical state of phospholipids 64
Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization 63
Conformational stability of the N-terminal region of MDM2 62
Anionic versus neutral Pt(II) complexes: The relevance of the charge for human serum albumin binding 61
Promising perspectives of the antiproliferative GPER inverse agonist ERα17p in breast cancer 61
Ecofriendly aminochalcogenation of alkenes: a green alternative to obtain compounds with potential anti-SARS-CoV-2 activity 61
Human enzyme PADI4 binds to the nuclear carrier Importin α3 59
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability 57
New insights into cancer: MDM2 binds to the citrullinating enzyme PADI4 57
Polyphenols from citrus Tacle® extract endowed with HMGCR inhibitory activity: an antihypercholesterolemia natural remedy 57
The intrinsically disordered, epigenetic factor RYBP binds to the citrullinating enzyme PADI4 in cancer cells 57
Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation 57
Catalytic activity of copper ions in the amyloid fibrillation of beta-lactoglobulin 56
Design of inhibitors of the intrinsically disordered protein NUPR1: balance between drug affinity and target function 56
New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides 56
Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations 56
Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells 55
The armadillo-repeat domain of Plakophilin 1 binds to human enzyme PADI4 55
Unveiling the binding between the armadillo-repeat domain of Plakophilin 1 and the intrinsically disordered transcriptional repressor RYBP 55
Seleno-functionalization of quercetin improves the non-covalent inhibition of Mpro and its antiviral activity in cells against SARS-CoV-2 53
Development of an efficient NUPR1 inhibitor with anticancer activity 53
Stereoselective and domain-specific effects of ibuprofen on the thermal stability of human serum albumin 53
The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3 52
Citrullinating enzyme PADI4 and transcriptional repressor RING1B bind in cancer cells 52
Warfarin increases thermal resistance of albumin through stabilization of the protein lobe that includes its binding site 52
The role of Lys525 on the head-group anchoring of fatty acids in the highest affinity binding site of albumin 50
Computational approaches for the discovery of GPER targeting compounds 50
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B 49
The muscle-relaxing C-terminal peptide from troponin I populates a nascent helix, facilitating binding to tropomyosin with a potent therapeutic effect 49
Effects of polar head nature and tail length of single-chain lipids on the conformational stability of β-lactoglobulin 48
A pilot study on the nutraceutical properties of the Citrus hybrid Tacle® as a dietary source of polyphenols for supplementation in metabolic disorders 48
Rutin is a low micromolar inhibitor of SARS-CoV-2 main protease 3CLpro: Implications for drug design of quercetin analogs 47
A phosphorylation-induced switch in the nuclear localization sequence of the intrinsically disordered NUPR1 hampers binding to importin 47
Targeting intrinsically disordered proteins involved in cancer 47
Dynamics and unfolding pathway of chimeric azurin variants: insights from molecular dynamics simulation 47
Association of ibuprofen at the polar/apolar interface of lipid membranes 46
Molecular dynamics of amicyanin reveals a conserved dynamical core for blue copper proteins 46
Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1) 46
Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation 46
ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents 45
Binding of warfarin differently affects the thermal behavior and chain packing of anionic, zwitterionic and cationic lipid membranes 44
Molecular simulations of proteins: From simplified physical interactions to complex biological phenomena 43
The chromatin nuclear protein NUPR1L is intrinsically disordered and binds to the same proteins as its paralogue 42
Identification by molecular docking of homoisoflavones from Leopoldia comosa as ligands of estrogen receptors 42
Ferric ions inhibit the amyloid fibrillation of β-lactoglobulin at high temperature 42
Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1 42
The peptide ERα17p is a GPER inverse agonist that exerts antiproliferative effects in breast cancer cells 42
The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73 42
CCR5/CXCR4 dual antagonism for the improvement of HIV infection therapy 42
Evidence of reduced flexibility in disulfide bridge-depleted azurin: a molecular dynamics simulation study 42
The isolated C-terminal nuclear localization sequence of the breast cancer metastasis suppressor 1 is disordered 41
Resveratrol induces chain interdigitation in DPPC cell membrane model systems 41
Targeting the stress-induced protein NUPR1 to treat pancreatic adenocarcinoma 40
Determinants of the pKa values of ionizable residues in an intrinsically disordered protein 40
I° Mercato delle Attività di Ricerca, ITA-Innovazione Tecnologica Applicata, 20 Dic 2005, 15-18 Mazo 2006 40
Stability of trans-resveratrol associated with transport proteins 40
Dynamics of the intrinsically disordered protein NUPR1 in isolation and in its fuzzy complexes with DNA and prothymosin α 40
Human importin α3 and its N-terminal truncated form, without the importin-β-binding domain, are oligomeric species with a low conformational stability in solution 39
Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis 39
Using simulations to provide the framework for experimental protein folding studies 39
Resveratrol induces thermal stabilization of human serum albumin and modulates the early aggregation stage 39
Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction 38
Dynamics and binding affinity of spin-labelled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation 38
Active site modeling in copper azurin molecular dynamics simulations 38
Human COA3 Is an Oligomeric Highly Flexible Protein in Solution 37
Nanomedicines meet disordered proteins: A shift from traditional materials and concepts to innovative polymers 37
Toward multitasking pharmacological COX-targeting agents: Non-steroidal anti-inflammatory prodrugs with antiproliferative effects 37
Sub-micromolar inhibition of SARS-CoV-2 3CLpro by natural compounds 36
Structural, dynamical and functional aspects of the inner motions in the blue copper protein azurin 36
Dynamics of the intrinsically disordered inhibitor IF7 of glutamine synthetase in isolation and in complex with its partner 36
The chromogranin A1-373 fragment reveals how a single change in the protein sequence exerts strong cardioregulatory effects by engaging neuropilin-1 36
Intrinsically disordered inhibitor of glutamine synthetase is a functional protein with random-coil-like pKa values 35
Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm 35
Residual helicity at the active site of the histidine phosphocarrier, HPr, modulates binding affinity to its natural partners 35
Dendrimers as competitors of protein-protein interactions of the intrinsically disordered nuclear chromatin protein NUPR1 35
Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites 35
The paralogue of the intrinsically disordered nuclear protein 1 has a nuclear localization sequence that binds to human importin α3 35
Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening 35
The early steps in the unfolding of azurin 34
Early stage aggregation of human serum albumin in the presence of metal ions 34
Thermally induced denaturation and aggregation of BLG-A: effect of the Cu2+ and Zn2+ metal ions 33
Crowding effects on the structure and dynamics of the intrinsically disordered nuclear chromatin protein NUPR1 33
The cyanobacterial ribosomal-associated protein LrtA from Synechocystis sp. PCC 6803 is an oligomeric protein in solution with chameleonic sequence properties 31
Solvent effect on the librational motion of spin-labelled hemoglobin 30
Identification of a drug targeting an intrinsically disordered protein involved in pancreatic adenocarcinoma 30
Coordination and dynamics of fatty acids in the highest-affinity binding site of human serum albumin 30
Totale 5.084
Categoria #
all - tutte 18.596
article - articoli 17.466
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 176
Totale 36.238


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 23 0 3 3
2024/20252.115 5 7 108 55 483 99 271 314 40 79 320 334
2025/20262.471 86 163 242 413 401 133 380 119 151 152 108 123
2026/2027628 130 152 346 0 0 0 0 0 0 0 0 0
Totale 5.243