COLOTTI, GIANNI
COLOTTI, GIANNI
Istituto di Biologia e Patologia Molecolari - IBPM
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate
2024 Marrocco, F.; Falvo, E.; Mosca, L.; Tisci, G.; Arcovito, A.; Reccagni, A.; Limatola, C.; Bernardini, R.; Ceci, P.; D'Alessandro, G.; Colotti, G.
Bcl-2 family inhibitors sensitize human cancer models to therapy
2023 Valentini, Elisabetta; Di Martile, Marta; Brignone, Matteo; Di Caprio, Marica; Manni, Isabella; Chiappa, Michela; Sergio, Ilaria; Chiacchiarini, Martina; Bazzichetto, Chiara; Conciatori, Fabiana; D'Aguanno, Simona; D'Angelo, Carmen; Ragno, Rino; Russillo, Michelangelo; Colotti, Gianni; Marchesi, Francesco; Bellone Maria, Laura; Dal Piaz, Fabrizio; Felli Maria, Pia; Damia, Giovanna; Del Bufalo, Donatella
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming
2023 Mattioli, Roberto; Ilari, Andrea; Colotti, Beatrice; Mosca, Luciana; Fazi, Francesco; Colotti, Gianni
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site
2023 Madia V.N.; Ialongo D.; Patacchini E.; Exertier C.; Antonelli L.; Colotti G.; Messore A.; Tudino V.; Saccoliti F.; Scipione L.; Ilari A.; Costi R.; Di Santo R.
Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands
2023 Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells
2023 Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways
2023 Tito, Claudia; Genovese, Ilaria; Giamogante, Flavia; Benedetti, Anna; Miglietta, Selenia; Barazzuol, Lucia; Cristiano, Loredana; Iaiza, Alessia; Carolini, Sabatino; De Angelis, Luciana; Masciarelli, Silvia; Nottola, Stefania Annarita; Familiari, Giuseppe; Petrozza, Vincenzo; Lauriola, Mattia; Tamagnone, Luca; Ilari, Andrea; Cali, Tito; Valdivia, Hector H.; Valdivia, Carmen R.; Colotti, Gianni; Fazi, Francesco
Widespread in vivo efficacy of The-0504: A conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers.
2023 Fracasso Giulio; Falvo Elisabetta; Tisci Giada; Sala Gianluca; Colotti Gianni; Cingarlini Sara; Tito Claudia; Bibbo Sandra; Frusteri Cristina; Tremante Elisa; Giordani Elena; Giacomini Patrizio; Ceci Pierpaolo.
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability
2022 Tramonti, A; Ghatge, Ms; Babor, Jt; Musayev, Fn; di Salvo, Ml; Barile, A; Colotti, G; Giorgi, A; Paredes, Sd; Donkor, Ak; Al Mughram, Mh; de CrécyLagard, V; Safo, Mk; Contestabile, R
ERp57 chaperon protein protects neuronal cells from A?-induced toxicity
2022 Di Risola D.; Ricci D.; Marrocco I.; Giamogante F.; Grieco M.; Francioso A.; VascoVidal A.; Mancini P.; Colotti G.; Mosca L.; Altieri F.
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design
2022 Fiorillo A.; Colotti G.; Exertier C.; Liuzzi A.; Seghetti F.; Salerno A.; Caciolla J.; Ilari A.
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach
2022 Battista, T; Federico, S; Brogi, S; Pozzetti, L; Khan, T; Butini, S; Ramunno, A; Fiorentino, E; Orsini, S; Di Muccio, T; Fiorillo, A; Exertier, C; Di Risola, D; Colotti, G; Gemma, S; Ilari, A; Campiani, G
Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules
2022 Valentini, Elisabetta; D'Aguanno, Simona; Di Martile, Marta; Montesano, Camilla; Ferraresi, Virginia; Patsilinakos, Alexandros; Sabatino, Manuela; Antonini, Lorenzo; Chiacchiarini, Martina; Valente, Sergio; Mai, Antonello; Colotti, Gianni; Ragno, Rino; Trisciuoglio, Daniela; Del Bufalo, Donatella
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin
2021 Annarita Fiorillo; Veronica Morea; Gianni Colotti; Andrea Ilari
Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding
2021 Flego, M; Colotti, G; Ascione, A; Dupuis, Ml; Petrucci, E; Riccioni, R; Andreotti, M; Raggi, C; Boe, A; Barca, S; Gellini, M; Vella, S; Mallano, A
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells
2021 Battista T.; Pascarella G.; Staid D.S.; Colotti G.; Rosati J.; Fiorillo A.; Casamassa A.; Vescovi A.L.; Giabbai B.; Semrau M.S.; Fanelli S.; Storici P.; Squitieri F.; Morea V.; Ilari A.
Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1
2021 Colotti G.; Failla C.M.; Lacal P.M.; Ungarelli M.; Ruffini F.; Di Micco P.; Orecchia A.; Morea V.
Structural basis of ubiquitination mediated by protein splicing in early Eukarya
2021 Chiarini, V; Fiorillo, A; Camerini, S; Crescenzi, M; Nakamura, S; Battista, T; Guidoni, L; Colotti, G; Ilari, A
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming
2021 Mosca, L; Ilari, A; Fazi, F; Assaraf, Yg; Colotti, G
A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories
2020 Mascia, A; Cirafici, Am; Bongiovanni, A; Colotti, G; Lacerra, G; Di Carlo, M; Digilio, Fa; Liguori, Gl; Lanati, A; Kisslinger, A
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate | 1-gen-2024 | Marrocco, F.; Falvo, E.; Mosca, L.; Tisci, G.; Arcovito, A.; Reccagni, A.; Limatola, C.; Bernardini, R.; Ceci, P.; D'Alessandro, G.; Colotti, G. | |
| Bcl-2 family inhibitors sensitize human cancer models to therapy | 1-gen-2023 | Valentini, Elisabetta; Di Martile, Marta; Brignone, Matteo; Di Caprio, Marica; Manni, Isabella; Chiappa, Michela; Sergio, Ilaria; Chiacchiarini, Martina; Bazzichetto, Chiara; Conciatori, Fabiana; D'Aguanno, Simona; D'Angelo, Carmen; Ragno, Rino; Russillo, Michelangelo; Colotti, Gianni; Marchesi, Francesco; Bellone Maria, Laura; Dal Piaz, Fabrizio; Felli Maria, Pia; Damia, Giovanna; Del Bufalo, Donatella | |
| Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming | 1-gen-2023 | Mattioli, Roberto; Ilari, Andrea; Colotti, Beatrice; Mosca, Luciana; Fazi, Francesco; Colotti, Gianni | |
| Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site | 1-gen-2023 | Madia V.N.; Ialongo D.; Patacchini E.; Exertier C.; Antonelli L.; Colotti G.; Messore A.; Tudino V.; Saccoliti F.; Scipione L.; Ilari A.; Costi R.; Di Santo R. | |
| Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands | 1-gen-2023 | Pascarella, Gianmarco; Antonelli, Lorenzo; Narzi, Daniele; Battista, Theo; Fiorillo, Annarita; Colotti, Gianni; Guidoni, Leonardo; Morea, Veronica; Ilari, Andrea | |
| Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells | 1-gen-2023 | Zwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello | |
| Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways | 1-gen-2023 | Tito, Claudia; Genovese, Ilaria; Giamogante, Flavia; Benedetti, Anna; Miglietta, Selenia; Barazzuol, Lucia; Cristiano, Loredana; Iaiza, Alessia; Carolini, Sabatino; De Angelis, Luciana; Masciarelli, Silvia; Nottola, Stefania Annarita; Familiari, Giuseppe; Petrozza, Vincenzo; Lauriola, Mattia; Tamagnone, Luca; Ilari, Andrea; Cali, Tito; Valdivia, Hector H.; Valdivia, Carmen R.; Colotti, Gianni; Fazi, Francesco | |
| Widespread in vivo efficacy of The-0504: A conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers. | 1-gen-2023 | Fracasso Giulio; Falvo Elisabetta; Tisci Giada; Sala Gianluca; Colotti Gianni; Cingarlini Sara; Tito Claudia; Bibbo Sandra; Frusteri Cristina; Tremante Elisa; Giordani Elena; Giacomini Patrizio; Ceci Pierpaolo. | |
| Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability | 1-gen-2022 | Tramonti, A; Ghatge, Ms; Babor, Jt; Musayev, Fn; di Salvo, Ml; Barile, A; Colotti, G; Giorgi, A; Paredes, Sd; Donkor, Ak; Al Mughram, Mh; de CrécyLagard, V; Safo, Mk; Contestabile, R | |
| ERp57 chaperon protein protects neuronal cells from A?-induced toxicity | 1-gen-2022 | Di Risola D.; Ricci D.; Marrocco I.; Giamogante F.; Grieco M.; Francioso A.; VascoVidal A.; Mancini P.; Colotti G.; Mosca L.; Altieri F. | |
| Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design | 1-gen-2022 | Fiorillo A.; Colotti G.; Exertier C.; Liuzzi A.; Seghetti F.; Salerno A.; Caciolla J.; Ilari A. | |
| Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach | 1-gen-2022 | Battista, T; Federico, S; Brogi, S; Pozzetti, L; Khan, T; Butini, S; Ramunno, A; Fiorentino, E; Orsini, S; Di Muccio, T; Fiorillo, A; Exertier, C; Di Risola, D; Colotti, G; Gemma, S; Ilari, A; Campiani, G | |
| Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules | 1-gen-2022 | Valentini, Elisabetta; D'Aguanno, Simona; Di Martile, Marta; Montesano, Camilla; Ferraresi, Virginia; Patsilinakos, Alexandros; Sabatino, Manuela; Antonini, Lorenzo; Chiacchiarini, Martina; Valente, Sergio; Mai, Antonello; Colotti, Gianni; Ragno, Rino; Trisciuoglio, Daniela; Del Bufalo, Donatella | |
| Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin | 1-gen-2021 | Annarita Fiorillo; Veronica Morea; Gianni Colotti; Andrea Ilari | |
| Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding | 1-gen-2021 | Flego, M; Colotti, G; Ascione, A; Dupuis, Ml; Petrucci, E; Riccioni, R; Andreotti, M; Raggi, C; Boe, A; Barca, S; Gellini, M; Vella, S; Mallano, A | |
| Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells | 1-gen-2021 | Battista T.; Pascarella G.; Staid D.S.; Colotti G.; Rosati J.; Fiorillo A.; Casamassa A.; Vescovi A.L.; Giabbai B.; Semrau M.S.; Fanelli S.; Storici P.; Squitieri F.; Morea V.; Ilari A. | |
| Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1 | 1-gen-2021 | Colotti G.; Failla C.M.; Lacal P.M.; Ungarelli M.; Ruffini F.; Di Micco P.; Orecchia A.; Morea V. | |
| Structural basis of ubiquitination mediated by protein splicing in early Eukarya | 1-gen-2021 | Chiarini, V; Fiorillo, A; Camerini, S; Crescenzi, M; Nakamura, S; Battista, T; Guidoni, L; Colotti, G; Ilari, A | |
| Taxanes in cancer treatment: Activity, chemoresistance and its overcoming | 1-gen-2021 | Mosca, L; Ilari, A; Fazi, F; Assaraf, Yg; Colotti, G | |
| A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories | 1-gen-2020 | Mascia, A; Cirafici, Am; Bongiovanni, A; Colotti, G; Lacerra, G; Di Carlo, M; Digilio, Fa; Liguori, Gl; Lanati, A; Kisslinger, A |