Advances in asymmetric synthesis of biologically active molecules using heterocycles as building blocks

The stereoselective and versatile approach to enantiomerically pure bioactive substances where heterocyclic building blocks are involved in the stereoselective key carbon-carbon bond formation and then transformed in order to introduce suitable functional groups in the target molecules, has widely shown its utility. In this review we report recent works focused on new asymmetric procedures for the synthesis of enantiopure biofunctional molecules based on this methodology.