The synthesis of 5-(alditol-1-C-yl)-hydantoin derivatives was performed via diastereoselective aldol-type addition of 1,3- dibenzyl-hydantoin to enantiopure aldehydo sugars. Starting from the D-ribo-configured 5-(alditol-1-C-yl)-hydantoin template, the synthesis of (2R,3S,4R)-3,4,5-trihydroxynorvaline was carried out.
Diastereoselective synthesis of 5-(alditol-1-C-yl)-hydantoins and their use as precursors of polyhydroxylated a-amino acids
Ulgheri F;Crisma M;Spanu P
2004
Abstract
The synthesis of 5-(alditol-1-C-yl)-hydantoin derivatives was performed via diastereoselective aldol-type addition of 1,3- dibenzyl-hydantoin to enantiopure aldehydo sugars. Starting from the D-ribo-configured 5-(alditol-1-C-yl)-hydantoin template, the synthesis of (2R,3S,4R)-3,4,5-trihydroxynorvaline was carried out.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
