In the hospital Intensive Care Units (ICU) there is an even greater demand by the physicians for the continuous immunosuppressant drug monitoring in the transplanted patient therapy, in order to avoid different risks and diseases which may occur as result of some drug dosage related effect, such the rejection crisis or sepsis. Here we present a novel design of a point of care testing (POCT) device for the drug dose--adjustment in this kind of patients. The working principle of the device will be discussed. Preliminary tests on the immunoassay strategies for immunosuppressant drugs recognition such as on the optical chip realization and characterization are reported.
A point-of-care device for immunosuppressants monitoring in transplanted patients
Berrettoni C;Trono Cosimo;Tombelli Sara;Giannetti Ambra;Berneschi Simone;Baldini Francesco;Grimaldi Immacolata Angelica;Persichetti Gianluca;Testa Genni;Bernini Romeo;
2015
Abstract
In the hospital Intensive Care Units (ICU) there is an even greater demand by the physicians for the continuous immunosuppressant drug monitoring in the transplanted patient therapy, in order to avoid different risks and diseases which may occur as result of some drug dosage related effect, such the rejection crisis or sepsis. Here we present a novel design of a point of care testing (POCT) device for the drug dose--adjustment in this kind of patients. The working principle of the device will be discussed. Preliminary tests on the immunoassay strategies for immunosuppressant drugs recognition such as on the optical chip realization and characterization are reported.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
