This study indicates that the longer the time from PV/ET to SMF, the larger the spleen. CALR genotype is associated to a more slowly progressive disease. Finally, chromosomal abnormalities are more associated with the presence of blast cells than with time to progression and this reinforces the concept that SMF is not related to PV/ET clonal evolution
Clinical Phenotype and Genotype Correlations with Time to Progression into Post Polycythemia Vera and Post Essential Thrombocythemia Myelofibrosis
Toni Giorgino;
2017
Abstract
This study indicates that the longer the time from PV/ET to SMF, the larger the spleen. CALR genotype is associated to a more slowly progressive disease. Finally, chromosomal abnormalities are more associated with the presence of blast cells than with time to progression and this reinforces the concept that SMF is not related to PV/ET clonal evolutionFile in questo prodotto:
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