The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom at position 8 attacks guanosine monophosphate (kr > 109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy.
Fluoroquinolones as potential photochemotherapeutic agents: covalent addition to guanosine monophosphate
I Manet;S Monti;
2010
Abstract
The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom at position 8 attacks guanosine monophosphate (kr > 109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy.File in questo prodotto:
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