Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10-15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.

An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children

Fabio Cibella;Giovanna Cilluffo;Salvatore Fasola;Riccardo Alessandro;Giovanni Viegi;Stefania La Grutta
2019

Abstract

Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10-15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.
2019
Istituto di biomedicina e di immunologia molecolare - IBIM - Sede Palermo
Istituto di Fisiologia Clinica - IFC
Asthma
Rhino-conjunctivitis
Sicilian children
Genetics
SNPs
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Descrizione: An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/351735
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