Summary: Abnormal karyotype was found in 34.1% of SMF patients and is over- represented in post-PV MF. No different distribution was detected among genotypes. Abnormal karyotype was associated with lower platelet count, larger splenomegaly, higher circulating blasts, consti- tutional symptoms and inferior survival. Among subtypes, MK re- mained the most powerful predictor of outcome.
CYTOGENETIC ABNORMALITIES IN POST-POLYCYTHEMIA VERA AND POST-ESSENTIAL THROMBOCYTHEMIA MYELOFIBROSIS: CORRELATIONS WITH GENOTYPE AND PHENOTYPE IN THE MYSEC STUDY
Giorgino T;
2017
Abstract
Summary: Abnormal karyotype was found in 34.1% of SMF patients and is over- represented in post-PV MF. No different distribution was detected among genotypes. Abnormal karyotype was associated with lower platelet count, larger splenomegaly, higher circulating blasts, consti- tutional symptoms and inferior survival. Among subtypes, MK re- mained the most powerful predictor of outcome.File in questo prodotto:
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