Wnt signaling and mitochondrial fitness are both important for cell fate. Costa et al. demonstrate that the reduction of mitochondrial ATP production leads to the induction of ER stress and, in turn, decreases canonical Wnt/?-catenin signaling in vitro and in vivo.
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
Zoratti M;Szabo I;
2019
Abstract
Wnt signaling and mitochondrial fitness are both important for cell fate. Costa et al. demonstrate that the reduction of mitochondrial ATP production leads to the induction of ER stress and, in turn, decreases canonical Wnt/?-catenin signaling in vitro and in vivo.File in questo prodotto:
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