Guardiola et al. investigate intrinsic cellto- cell variability in mouse-activated satellite cell (ASC) population in skeletal muscle regeneration. ASCs display a continuumof metastable cell states along with CRIPTO expression gradient, whose dynamic fluctuation enables rapid adaptation to changing microenvironment and preserves muscle stem cell population diversity
Cripto-based micro-heterogeneity of mouse muscle satellite cells enables adaptive response to regenerative micro-environment
Ombretta Guardiola
;Laura Pisapia;Gennaro Andolfi;Eduardo J Patriarca;Gabriella Minchiotti
2023
Abstract
Guardiola et al. investigate intrinsic cellto- cell variability in mouse-activated satellite cell (ASC) population in skeletal muscle regeneration. ASCs display a continuumof metastable cell states along with CRIPTO expression gradient, whose dynamic fluctuation enables rapid adaptation to changing microenvironment and preserves muscle stem cell population diversityFile in questo prodotto:
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