Phytochemical investigation from the stems of Alibertia edulis led to the isolation and identification of a new iridoid 6b-hydroxy-7-epigardoside methyl ester (1) and a new saponin 3b-O-[a-l-rhamnopyranosyl-( 1!2)-O-b-d-glucopyranosyl-(1!2)-O-b-d-glucopyranosyl]-28-O-b-d-glucopyranoside pomolate (2), along with three known compounds, shanzhiside methyl ester (3), ixoside (4), and 3,4,5- trimethoxyphenyl 1-O-b-d-apiofuranosyl-(1!6)-O-b-d-glucopyranoside (5). The structures of 1 and 2 were established on the basis of their spectroscopic data. Iridoid 1 and saponin 2 exhibited moderate inhibitory activities against Candida albicans and C. krusei in a dilution assay.
New antifungal terpenoid glycosides from Alibertia edulis (Rubiaceae).
Carbone V;
2008
Abstract
Phytochemical investigation from the stems of Alibertia edulis led to the isolation and identification of a new iridoid 6b-hydroxy-7-epigardoside methyl ester (1) and a new saponin 3b-O-[a-l-rhamnopyranosyl-( 1!2)-O-b-d-glucopyranosyl-(1!2)-O-b-d-glucopyranosyl]-28-O-b-d-glucopyranoside pomolate (2), along with three known compounds, shanzhiside methyl ester (3), ixoside (4), and 3,4,5- trimethoxyphenyl 1-O-b-d-apiofuranosyl-(1!6)-O-b-d-glucopyranoside (5). The structures of 1 and 2 were established on the basis of their spectroscopic data. Iridoid 1 and saponin 2 exhibited moderate inhibitory activities against Candida albicans and C. krusei in a dilution assay.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
