The original version of this article unfortunately contained a mistake. The table 2 caption should read as Table 2 Association results in the replication sample. For each SNP, the association data in the replication cohort and results from the meta-analyses between discovery and replication cohorts (including and not including the NonIT-EUR cohort) are reported. Results for the genome-wide Italian approach are reported in the upper panel (A), while results for the approaches including the NonIT-EUR are reported in panel B (discovery sample derived from ITAGWAS alone) and C (SNPs identified through the meta-analysis between ITAGWAS and ITAiChip). A1: reference allele (the same as defined in table 1); OR: odds ratio; L95: lower-bound of 95%-confidence interval; U95: upper bound of 95%-confidence interval; P: P-value of association; I2: heterogeneity index. The SNPs with an association beyond the multiple testing correction (Bonferroni threshold of P-value: 1.7 × 10–3, 3.6 × 10–3, 6.25 × 10–3 respectively for A, B and C) are highlighted in bold. No significant association was found in the replication cohort for SNPs selected through the Italian genome-wide approach. The original article has been corrected.

Correction to: A multi-step genomic approach prioritized TBKBP1 gene as relevant for multiple sclerosis susceptibility

Anand, Santosh;Mangano, Eleonora;Bordoni, Roberta;Cusi, Daniele;Leone, Maurizio;De Bellis, Gianluca;
2022

Abstract

The original version of this article unfortunately contained a mistake. The table 2 caption should read as Table 2 Association results in the replication sample. For each SNP, the association data in the replication cohort and results from the meta-analyses between discovery and replication cohorts (including and not including the NonIT-EUR cohort) are reported. Results for the genome-wide Italian approach are reported in the upper panel (A), while results for the approaches including the NonIT-EUR are reported in panel B (discovery sample derived from ITAGWAS alone) and C (SNPs identified through the meta-analysis between ITAGWAS and ITAiChip). A1: reference allele (the same as defined in table 1); OR: odds ratio; L95: lower-bound of 95%-confidence interval; U95: upper bound of 95%-confidence interval; P: P-value of association; I2: heterogeneity index. The SNPs with an association beyond the multiple testing correction (Bonferroni threshold of P-value: 1.7 × 10–3, 3.6 × 10–3, 6.25 × 10–3 respectively for A, B and C) are highlighted in bold. No significant association was found in the replication cohort for SNPs selected through the Italian genome-wide approach. The original article has been corrected.
2022
Istituto di Tecnologie Biomediche - ITB
genome wide association study
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/519341
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