VHEE beams (100-250 MeV) are being considered for treating deep-seated tumors using FLASH radiotherapy. Laser-plasma acceleration (LPA) through the Laser Wakefield Acceleration (LWFA) mechanism enables acceleration gradients orders of magnitude higher than conventional RF accelerators, making LPA an ideal candidate for compactly generating VHEE for clinical use. We present recent results on the dosimetric characterization of an LWFA-based VHEE source at ILIL and its application to in vitro radiobiology.

Laser-plasma acceleration of very high energy electron (VHEE) beams: using ultra high dose rate pulses for in vitro radiobiology studies

M. Salvadori;G. Bandini;A. Borghini;F. Baffigi;A. Fregosi;L. Fulgentini;D. Gregocki;P. Koester;L. Labate;D. Palla;S. Vlachos;C. Panaino;F. Avella;
2024

Abstract

VHEE beams (100-250 MeV) are being considered for treating deep-seated tumors using FLASH radiotherapy. Laser-plasma acceleration (LPA) through the Laser Wakefield Acceleration (LWFA) mechanism enables acceleration gradients orders of magnitude higher than conventional RF accelerators, making LPA an ideal candidate for compactly generating VHEE for clinical use. We present recent results on the dosimetric characterization of an LWFA-based VHEE source at ILIL and its application to in vitro radiobiology.
2024
Istituto Nazionale di Ottica - INO - Sede Secondaria di Pisa
Istituto di Fisiologia Clinica - IFC
Laser-plasma acceleration, VHEE, radiobiology
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/537751
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