This work demonstrates that living neuronal networks can serve as effective computational substrates within a reservoir computing framework. By leveraging the intrinsic dynamics of biological systems, we open a promising pathway towards neuromorphic architectures that combine energy efficiency, adaptability, and biological plausibility. Our experiments on static pattern recognition tasks confirm the feasibility of this approach and highlight its potential for future applications in AI and neuroscience. Notably, our preliminary study on this topic, presented at the ICCV 2025 Workshop “2nd Workshop on Human-inspired Computer Vision”, received a Best Paper Award, and subsequent work was published at ICONIP 2025, underscoring the originality and scientific relevance of this research. Moving forward, we aim to extend BRC to more complex tasks and explore learning mechanisms within the biological reservoir, paving the way for adaptive bio-hybrid system.

Biological reservoir computing: harnessing living neurons for AI

Ciampi Luca;Iannello Ludovico;Amato Giuseppe;Cremisi Federico;
2026

Abstract

This work demonstrates that living neuronal networks can serve as effective computational substrates within a reservoir computing framework. By leveraging the intrinsic dynamics of biological systems, we open a promising pathway towards neuromorphic architectures that combine energy efficiency, adaptability, and biological plausibility. Our experiments on static pattern recognition tasks confirm the feasibility of this approach and highlight its potential for future applications in AI and neuroscience. Notably, our preliminary study on this topic, presented at the ICCV 2025 Workshop “2nd Workshop on Human-inspired Computer Vision”, received a Best Paper Award, and subsequent work was published at ICONIP 2025, underscoring the originality and scientific relevance of this research. Moving forward, we aim to extend BRC to more complex tasks and explore learning mechanisms within the biological reservoir, paving the way for adaptive bio-hybrid system.
2026
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo" - ISTI
Neuronal networks, Reservoir computing, Pattern recognition
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Descrizione: Biological Reservoir Computing: Harnessing Living Neurons for AI
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/580921
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