Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications. For instance, laser-driven VHEE beams are envisaged to offer suitable compact accelerators for the promising field of FLASH radiotherapy. Radiobiology experiments carried out using laser-driven beams require the real-time knowledge of the dose delivered to the sample. We have developed an online dose monitoring procedure, using an Integrating Current Transformer (ICT) coupled to a suitable collimator, that allows the estimation of the delivered dose on a shot-to-shot basis under suitable assumptions. The cross-calibration of the measured charge with standard offline dosimetry measurements carried out with RadioChromic Films (RCFs) is discussed, demonstrating excellent correlation between the two measurements.

Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications

David Gregocki;Luca Umberto Labate;Simona Piccinini;Federico Avella;Federica Baffigi;Gabriele Bandini;Fernando Brandi;Lorenzo Fulgentini;Daniele Palla;Martina Salvadori;Simon Gerasimos Vlachos;Leonida Antonio Gizzi
2025

Abstract

Laser-accelerated electron beams, in the so-called Very High-Energy Electron (VHEE) energy range, are of great interest for biomedical applications. For instance, laser-driven VHEE beams are envisaged to offer suitable compact accelerators for the promising field of FLASH radiotherapy. Radiobiology experiments carried out using laser-driven beams require the real-time knowledge of the dose delivered to the sample. We have developed an online dose monitoring procedure, using an Integrating Current Transformer (ICT) coupled to a suitable collimator, that allows the estimation of the delivered dose on a shot-to-shot basis under suitable assumptions. The cross-calibration of the measured charge with standard offline dosimetry measurements carried out with RadioChromic Films (RCFs) is discussed, demonstrating excellent correlation between the two measurements.
2025
Istituto Nazionale di Ottica - INO - Sede Secondaria di Pisa
integrating current transformer
laser plasma acceleration
radiochromic films
real-time dose monitoring
very high-energy electron beams
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Descrizione: Real-Time Dose Monitoring via Non-Destructive Charge Measurement of Laser-Driven Electrons for Medical Applications
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/584682
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