The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom in position 8 attacks guanine monophosphate (kr >109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy
First time reported 6,8 FQs photoogenerated triplet heteroarylcation direct attack onto guanosine
Ilse Manet;Sandra Monti
2010
Abstract
The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom in position 8 attacks guanine monophosphate (kr >109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapyFile in questo prodotto:
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