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The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom in position 8 attacks guanine monophosphate (kr >109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy

First time reported 6,8 FQs photoogenerated triplet heteroarylcation direct attack onto guanosine

Ilse Manet;Sandra Monti
2010

Abstract

The triplet aryl cation photochemically generated from fluoroquinolones bearing a fluoro atom in position 8 attacks guanine monophosphate (kr >109 M-1s-1) and forms covalent adducts. The reaction is a model for the implementation of oxygen-independent photochemotherapy
2010
Istituto per la Sintesi Organica e la Fotoreattivita' - ISOF
Inglese
XXIII IUPAC Symposium on Photochemistry
07/2010
Ferrara
drug photochemistry
none
info:eu-repo/semantics/conferenceObject
Pretali, Luca; Fasani, Elisa; Albini, Angelo; Manet, Ilse; Monti, Sandra
275
04 Contributo in convegno::04.03 Poster in Atti di convegno
5
04.03 Poster in Atti di convegno
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/98736
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