ORRU', VALERIA

ORRU', VALERIA  

Istituto di Ricerca Genetica e Biomedica - IRGB - Sede Secondaria Lanusei (OG)  

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Immune and glial cell alterations in the rat brain after repeated exposure to the synthetic cannabinoid JWH-018 1-gen-2024 Pintori, N; Mostallino, R; Spano, E; Orrù, V; Piras, Mg; Castelli, Mp; De Luca, Ma
Implications of disease-modifying therapies for multiple sclerosis on immune cells and response to COVID-19 vaccination 1-gen-2024 Orru', Valeria; Serra, V.; Marongiu, M.; Lai, S.; Lodde, V.; Zoledziewska, M.; Steri, M.; Loizedda, A.; Lobina, M.; Piras, M. G.; Virdis, F.; Delogu, G.; Marini, M. G.; Mingoia, M.; Floris, M.; Masala, M.; Castelli, M. P.; Mostallino, R.; Frau, J.; Lorefice, L.; Farina, G.; Fronza, M.; Carmagnini, D.; Carta, E.; Pilotto, S.; Chessa, P.; Devoto, M.; Castiglia, P.; Solla, P.; Zarbo, R. I.; Idda, M. L.; Pitzalis, M.; Cocco, E.; Fiorillo, E.; Cucca, F.
Transcriptome organization of white blood cells through gene co-expression network analysis in a large RNA-seq dataset 1-gen-2024 Forabosco, P.; Pala, M.; Crobu, F.; Diana, M. A.; Marongiu, M.; Cusano, R.; Angius, A.; Steri, M.; Orru, V.; Schlessinger, D.; Fiorillo, E.; Devoto, M.; Cucca, F.
Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. 1-gen-2024 Huffman, Je; Nicolas, J; Hahn, J; Heath, As; Raffield, Lm; Yanek, Lr; Brody, Ja; Thibord, F; Almasy, L; Bartz, Tm; Bielak, Lf; Bowler, Rp; Carrasquilla, Gd; Chasman, Di; Chen, Mh; Emmert, Db; Ghanbari, M; Haessle, J; Hottenga, Jj; Kleber, Me; Le, Nq; Lee, J; Lewis, Jp; Li-Gao, R; Luan, J; Malmberg, A; Mangino, M; Marioni, Re; Martinez-Perez, A; Pankratz, N; Polasek, O; Richmond, A; Rodriguez, Ba; Rotter, Ji; Steri, M; Suchon, P; Trompet, S; Weiss, S; Zare, M; Auer, P; Cho, Mh; Christofidou, P; Davies, G; de Geus, E; Deleuze, Jf; Delgado, Ge; Ekunwe, L; Faraday, N; Gögele, M; Greinacher, A; He, G; Howard, T; Joshi, Pk; Kilpeläinen, To; Lahti, J; Linneberg, A; Naitza, S; Noordam, R; Paüls-Vergés, F; Rich, Ss; Rosendaal, Fr; Rudan, I; Ryan, Ka; Souto, Jc; van Rooij, Fj; Wang, H; Zhao, W; Becker, Lc; Beswick, A; Brown, Mr; Cade, Be; Campbell, H; Cho, K; Crapo, Jd; Curran, Je; de Maat, Mp; Doyle, M; Elliott, P; Floyd, Js; Fuchsberger, C; Grarup, N; Guo, X; Harris, Se; Hou, L; Kolcic, I; Kooperberg, C; Menni, C; Nauck, M; O'Connell, Jr; Orrù, V; Psaty, Bm; Räikkönen, K; Smith, Ja; Soria, Jm; Stott, Dj; van Hylckama Vlieg, A; Watkins, H; Willemsen, G; Wilson, P; Ben-Shlomo, Y; Blangero, J; Boomsma, D; Cox, Sr; Dehghan, A; Eriksson, Jg; Fiorillo, E; Fornage, M; Hansen, T; Hayward, C; Ikram, Ma; Jukema, Jw; Kardia, Sl; Lange, La; März, W; Mathias, Ra; Mitchell, Bd; Mook-Kanamori, Do; Morange, Pe; Pedersen, O; Pramstaller, Pp; Redline, S; Reiner, A; Ridker, Pm; Silverman, Ek; Spector, Td; Völker, U; Wareham, N; Wilson, Jf; Yao, J; VA Million Veteran, Program; NHLBI Trans-Omics for Precision Medicine (TOPMed), Consortium; Trégouët, Da; Johnson, Ad; Wolberg, As; de Vries, Ps; Sabater-Lleal, M; Morrison, Ac; Smith, Nl.
Effect of Genetic Factors, Age and Sex on Levels of Circulating Extracellular Vesicles and Platelets 1-gen-2023 Orrù, V; Virdis, F; Marongiu, M; Serra, V; Schlessinger, D; Devoto, M; Cucca, F; Fiorillo, E.
GWAS of genetic factors affecting white blood cell morphological parameters in Sardinians uncovers influence of chromosome 11 innate immunity gene cluster on eosinophil morphology. 1-gen-2023 Marongiu, M; Pérez-Mejías, G; Orrù, V; Steri, M; Sidore, C; Díaz-Quintana, A; Mulas, A; Busonero, F; Maschio, A; Walter, K; Tardaguila, M; Akbari, P; Soranzo, N; Fiorillo, E; Gorospe, M; Schlessinger, D; Díaz-Moreno, I; Cucca, F; Zoledziewska, M.
Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection 1-gen-2023 Ahuja, Sk; Manoharan, Ms; Lee, Gc; Mckinnon, Lr; Meunier, Ja; Steri, M; Harper, N; Fiorillo, E; Smith, Am; Restrepo, Mi; Branum, Ap; Bottomley, Mj; Orrù, V; Jimenez, F; Carrillo, A; Pandranki, L; Winter, Ca; Winter, La; Gaitan, Aa; Moreira, Ag; Walter, Ea; Silvestri, G; King, Cl; Zheng, Yt; Zheng, Hy; Kimani, J; Blake Ball, T; Plummer, Fa; Fowke, Kr; Harden, Pn; Wood, Kj; Ferris, Mt; Lund, Jm; Heise, Mt; Garrett, N; Canady, Kr; Abdool Karim, Ss; Little, Sj; Gianella, S; Smith, Dm; Letendre, S; Richman, Dd; Cucca, F; Trinh, H; Sanchez-Reilly, S; Hecht, Jm; Cadena Zuluaga, Ja; Anzueto, A; Pugh, Ja; South Texas Veterans Health Care System COVID-19, Team; Agan, Bk; Root-Bernstein, R; Clark, Ra; Okulicz, Jf; He, W
Quantifying the Detrimental Effects of Multiple Freeze/Thaw Cycles on Primary Human Lymphocyte Survival and Function 1-gen-2023 Serra, V; Fiorillo, E; Cucca, F; Orrù, V.
The PPARalpha agonist fenofibrate reduces the cytokine imbalance in a maternal immune activation model of schizophrenia 1-gen-2023 Mostallino R; Santoni M; Sagheddu C; Serra V; Orrù V; Pistis M; Castelli MP.
Adolescent self-administration of the synthetic cannabinoid receptor agonist JWH-018 induces neurobiological and behavioral alterations in adult male mice. 1-gen-2022 Margiani, G; Castelli, Mp; Pintori, N; Frau, R; Ennas, Mg; Pagano Zottola, Ac; Orrù, V; Serra, V; Fiorillo, E; Fadda, P; Marsicano, G; De Luca, Ma.
Autoimmunity is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension 1-gen-2022 Jones, Rj; De Bie, Emdd; Groves, E; Zalewska, Ki; Swietlik, Em; Treacy, Cm; Martin, Jm; Polwarth, G; Li, W; Guo, J; Baxendale, He; Coleman, S; Savinykh, N; Coghlan, Jg; Corris, Pa; Howard, Ls; Johnson, Mk; Church, C; Kiely, Dg; Lawrie, A; Lordan, Jl; Mackenzie Ross, Rv; Pepke Zaba, J; Wilkins, Mr; Wort, Sj; Fiorillo, E; Orrù, V; Cucca, F; Rhodes, Cj; Gräf, S; Morrell, Nw; Mckinney, Ef; Wallace, C; Toshner, M; UK National PAH Cohort Study, Consortium.
Comparison of Whole Blood Cryopreservation Methods for Extensive Flow Cytometry Immunophenotyping 1-gen-2022 Serra, Valentina; Orru, Valeria; Lai, Sandra; Lobina, Monia; Steri, Maristella; Cucca, Francesco; Fiorillo, Edoardo
Genetic diversity fuels gene discovery for tobacco and alcohol use 1-gen-2022 Saunders, Grb; Wang, X; Chen, F; Jang, Sk; Liu, M; Wang, C; Gao, S; Jiang, Y; Khunsriraksakul, C; Otto, Jm; Addison, C; Akiyama, M; Albert, Cm; Aliev, F; Alonso, A; Arnett, Dk; Ashley-Koch, Ae; Ashrani, Aa; Barnes, Kc; Barr, Rg; Bartz, Tm; Becker, Dm; Bielak, Lf; Benjamin, Ej; Bis, Jc; Bjornsdottir, G; Blangero, J; Bleecker, Er; Boardman, Jd; Boerwinkle, E; Boomsma, Di; Boorgula, Mp; Bowden, Dw; Brody, Ja; Cade, Be; Chasman, Di; Chavan, S; Chen, Yi; Chen, Z; Cheng, I; Cho, Mh; Choquet, H; Cole, Jw; Cornelis, Mc; Cucca, F; Curran, Je; de Andrade, M; Dick, Dm; Docherty, Ar; Duggirala, R; Eaton, Cb; Ehringer, Ma; Esko, T; Faul, Jd; Fernandes Silva, L; Fiorillo, E; Fornage, M; Freedman, Bi; Gabrielsen, Me; Garrett, Me; Gharib, Sa; Gieger, C; Gillespie, N; Glahn, Dc; Gordon, Sd; Gu, Cc; Gu, D; Gudbjartsson, Df; Guo, X; Haessler, J; Hall, Me; Haller, T; Harris, Km; He, J; Herd, P; Hewitt, Jk; Hickie, I; Hidalgo, B; Hokanson, Je; Hopfer, C; Hottenga, J; Hou, L; Huang, H; Hung, Yj; Hunter, Dj; Hveem, K; Hwang, Sj; Hwu, Cm; Iacono, W; Irvin, Mr; Jee, Yh; Johnson, Eo; Joo, Yy; Jorgenson, E; Justice, Ae; Kamatani, Y; Kaplan, Rc; Kaprio, J; Kardia, Slr; Keller, Mc; Kelly, Tn; Kooperberg, C; Korhonen, T; Kraft, P; Krauter, K; Kuusisto, J; Laakso, M; Lasky-Su, J; Lee, Wj; Lee, Jj; Levy, D; L, Li; Li, K; Li, Y; Lin, K; Lind, Pa; Liu, C; Lloyd-Jones, Dm; Lutz, Sm; Ma, J; Mägi, R; Manichaikul, A; Martin, Ng; Mathur, R; Matoba, N; Mcardle, Pf; Mcgue, M; Mcqueen, Mb; Medland, Se; Metspalu, A; Meyers, Da; Millwood, Iy; Mitchell, Bd; Mohlke, Kl; Moll, M; Montasser, Me; Morrison, Ac; Mulas, A; Nielsen, Jb; North, Ke; Oelsner, Ec; Okada, Y; Orrù, V; Palmer, Nd; Palviainen, T; Pandit, A; Park, Sl; Peters, U; Peters, A; Peyser, Pa; Polderman, Tjc; Rafaels, N; Redline, S; Reed, Rm; Reiner, Ap; Rice, Jp; Rich, Ss; Richmond, Ne; Roan, C; Rotter, Ji; Rueschman, Mn; Runarsdottir, V; Saccone, Nl; Schwartz, Da; Shadyab, Ah; Shi, J; Shringarpure, Ss; Sicinski, K; Skogholt, Ah; Smith, Ja; Smith, Nl; Sotoodehnia, N; Stallings, Mc; Stefansson, H; Stefansson, K; Stitzel, Ja; Sun, X; Syed, M; Tal-Singer, R; Taylor, Ae; Taylor, Kd; Telen, Mj; Thai, Kk; Tiwari, H; Turman, C; Tyrfingsson, T; Wall, Tl; Walters, Rg; Weir, Dr; Weiss, St; White, Wb; Whitfield, Jb; Wiggins, Kl; Willemsen, G; Willer, Cj; Winsvold, Bs; Xu, H; Yanek, Lr; Yin, J; Young, Kl; Young, Ka; Yu, B; Zhao, W; Zhou, W; Zöllner, S; Zuccolo, L; 23andMe Research, Team; Biobank Japan, Project; Batini, C; Bergen, Aw; Bierut, Lj; David, Sp; Gagliano Taliun, Sa; Hancock, Db; Jiang, B; Munafò, Mr; Thorgeirsson, Te; Liu, Dj; Vrieze, S.
Genetic variant within CDK6 regulates immune response to palbociclib treatment 1-gen-2022 Serra, Valentina; Orru, Valeria; Steri, Maristella; Fiorillo, Edoardo; Cucca, Francesco; Zoledziewska, Magdalena
The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis 1-gen-2022 Fabre, Margarete A.; de Almeida, Jose Guillherme; Fiorillo, Edoardo; Mitchell, Emily; Damaskou, Aristi; Rak, Justyna; Orru, Valeria; Marongiu, Michele; Vijayabaskar, M. S.; Baxter, Joanna E.; Hardy, Claire; Abascal, Federico; Chapman, Michael Spencer; Williams, Nicholas; Nangalia, Jyoti; Martincorena, Inigo; Campbell, Peter J.; Mckinney, Eoin F.; Cucca, Francesco; Gerstung, Moritz; Vassiliou, George S.
Application of Genetic Studies to Flow Cytometry Data and Its Impact on Therapeutic Intervention for Autoimmune Disease 1-gen-2021 Orru, Valeria; Steri, Maristella; Cucca, Francesco; Fiorillo, Edoardo
Carotid Beta Stiffness Association with Thyroid Function 1-gen-2021 Delitala, Alessandro P.; Scuteri, Angelo; Fiorillo, Edoardo; Orru, Valeria; Lakatta, Edward G.; Schlessinger, David; Cucca, Francesco
Effect of Different Disease-Modifying Therapies on Humoral Response to BNT162b2 Vaccine in Sardinian Multiple Sclerosis Patients 1-gen-2021 Pitzalis, Maristella; Idda, Maria Laura; Lodde, Valeria; Loizedda, Annalisa; Lobina, Monia; Zoledziewska, Magdalena; Virdis, Francesca; Delogu, Giuseppe; Pirinu, Federica; Marini, Maria Giuseppina; Mingoia, Maura; Frau, Jessica; Lorefice, Lorena; Fronza, Marzia; Carmagnini, Daniele; Carta, Elisa; Orru, Valeria; Uzzau, Sergio; Solla, Paolo; Loi, Federica; Devoto, Marcella; Steri, Maristella; Fiorillo, Edoardo; Floris, Matteo; Zarbo, Ignazio Roberto; Cocco, Eleonora; Cucca, Francesco
Immunologic resilience and COVID-19 survival advantage 1-gen-2021 Lee, Grace C.; Restrepo, Marcos I.; Harper, Nathan; Manoharan, Muthu Saravanan; Smith, Alisha M.; Meunier, Justin A.; Sanchez-Reilly, Sandra; Ehsan, Aamir; Branum, Anne P.; Winter, Caitlyn; Winter, Lauryn; Jimenez, Fabio; Pandranki, Lavanya; Carrillo, Andrew; Perez, Graciela L.; Anzueto, Antonio; Trinh, Hanh; Lee, Monica; Hecht, Joan M.; Martinez-Vargas, Celida; Sehgal, Raj T.; Cadena, Jose; Walter, Elizabeth A.; Oakman, Kimberly; Benavides, Raymond; Pugh, Jacqueline A.; Letendre, Scott; Steri, Maristella; Orru, Valeria; Fiorillo, Edoardo; Cucca, Francesco; Moreira, Alvaro G.; Zhang, Nu; Leadbetter, Elizabeth; Agan, Brian K.; Richman, Douglas D.; He, Weijing; Clark, Robert A.; Okulicz, Jason F.; Ahuja, Sunil K.
Model-based assessment of replicability for genome-wide association meta-analysis 1-gen-2021 Mcguire, D.; Jiang, Y.; Liu, M.; Weissenkampen, J. D.; Eckert, S.; Yang, L.; Chen, F.; Liu, M.; Jiang, Y.; Wedow, R.; Li, Y.; Brazel, D. M.; Chen, F.; Datta, G.; Davila-Velderrain, J.; Mcguire, D.; Tian, C.; Zhan, X.; Choquet, H.; Docherty, A. R.; Faul, J. D.; Foerster, J. R.; Fritsche, L. G.; Gabrielsen, M. E.; Gordon, S. D.; Haessler, J.; Hottenga, J. -J.; Huang, H.; Jang, S. -K.; Jansen, P. R.; Ling, Y.; Ma gi, R.; Matoba, N.; Mcmahon, G.; Mulas, A.; Orru, V.; Palviainen, T.; Pandit, A.; Reginsson, G. W.; Skogholt, A. H.; Smith, J. A.; Taylor, A. E.; Turman, C.; Willemsen, G.; Young, H.; Young, K. A.; Zajac, G. J. M.; Zhao, W.; Zhou, W.; Bjornsdottir, G.; Boardman, J. D.; Boehnke, M.; Boomsma, D. I.; Chen, C.; Cucca, F.; Davies, G. E.; Eaton, C. B.; Ehringer, M. A.; Esko, T.; Fiorillo, E.; Gillespie, N. A.; Gudbjartsson, D. F.; Haller, T.; Harris, K. M.; Heath, A. C.; Hewitt, J. K.; Hickie, I. B.; Hokanson, J. E.; Hopfer, C. J.; Hunter, D. J.; Iacono, W. G.; Johnson, E. O.; Kamatani, Y.; Kardia, S. L. R.; Keller, M. C.; Kellis, M.; Kooperberg, C.; Kraft, P.; Krauter, K. S.; Laakso, M.; Lind, P. A.; Loukola, A.; Lutz, S. M.; Madden, P. A. F.; Martin, N. G.; Mcgue, M.; Mcqueen, M. B.; Medland, S. E.; Metspalu, A.; Mohlke, K. L.; Nielsen, J. B.; Okada, Y.; Peters, U.; Polderman, T. J. C.; Posthuma, D.; Reiner, A. P.; Rice, J. P.; Rimm, E.; Rose, R. J.; Runarsdottir, V.; Stallings, M. C.; Stanca kova, A.; Stefansson, H.; Thai, K. K.; Tindle, H. A.; Tyrfingsson, T.; Wall, T. L.; Weir, D. R.; Weisner, C.; Whitfield, J. B.; Winsvold, B. S.; Yin, J.; Zuccolo, L.; Bierut, L. J.; Hveem, K.; Lee, J. J.; Munafo, M. R.; Saccone, N. L.; Willer, C. J.; Cornelis, M. C.; David, S. P.; Hinds, D.; Jorgenson, E.; Kaprio, J.; Stitzel, J. A.; Stefansson, K.; Thorgeirsson, T. E.; Abecasis, G.; Liu, D. J.; Vrieze, S.; Berg, A.; Vrieze, S.; Jiang, B.; Li, Q.; Liu, D. J.