CNR Institutional Research Information System

PAPPALARDO, GIUSEPPE
 Distribuzione geografica
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Continente #
AS - Asia 3.511
NA - Nord America 1.935
EU - Europa 973
SA - Sud America 618
AF - Africa 71
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.114
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Nazione #
US - Stati Uniti d'America 1.827
SG - Singapore 1.429
CN - Cina 859
BR - Brasile 501
VN - Vietnam 360
HK - Hong Kong 348
IT - Italia 299
FR - Francia 215
NL - Olanda 170
KR - Corea 152
JP - Giappone 75
IN - India 70
BD - Bangladesh 63
DE - Germania 58
CA - Canada 51
GB - Regno Unito 48
AR - Argentina 44
FI - Finlandia 44
ZA - Sudafrica 29
MX - Messico 26
ID - Indonesia 25
IL - Israele 24
PL - Polonia 19
EC - Ecuador 18
ES - Italia 18
CL - Cile 17
PK - Pakistan 16
AT - Austria 15
IQ - Iraq 12
CO - Colombia 11
IE - Irlanda 11
RU - Federazione Russa 11
SA - Arabia Saudita 11
UZ - Uzbekistan 11
JM - Giamaica 9
UA - Ucraina 9
DZ - Algeria 8
EG - Egitto 8
PE - Perù 8
PY - Paraguay 8
MA - Marocco 6
PH - Filippine 6
SE - Svezia 6
VE - Venezuela 6
CH - Svizzera 5
DK - Danimarca 5
KE - Kenya 5
LB - Libano 5
LV - Lettonia 5
MY - Malesia 5
TR - Turchia 5
UY - Uruguay 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
AU - Australia 4
BE - Belgio 4
CZ - Repubblica Ceca 4
KH - Cambogia 4
TH - Thailandia 4
TN - Tunisia 4
BY - Bielorussia 3
CR - Costa Rica 3
CY - Cipro 3
LT - Lituania 3
RO - Romania 3
CI - Costa d'Avorio 2
GE - Georgia 2
GR - Grecia 2
HN - Honduras 2
HU - Ungheria 2
JO - Giordania 2
LK - Sri Lanka 2
MD - Moldavia 2
OM - Oman 2
PA - Panama 2
PT - Portogallo 2
SN - Senegal 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
AM - Armenia 1
AW - Aruba 1
BG - Bulgaria 1
BH - Bahrain 1
BM - Bermuda 1
BS - Bahamas 1
BZ - Belize 1
CU - Cuba 1
DJ - Gibuti 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GA - Gabon 1
GH - Ghana 1
GT - Guatemala 1
GU - Guam 1
KN - Saint Kitts e Nevis 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
Totale 7.099
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Città #
Singapore 857
Santa Clara 488
Hefei 344
Hong Kong 341
San Jose 258
Ashburn 175
Lauterbourg 168
Seoul 149
Beijing 130
Ho Chi Minh City 130
Los Angeles 118
Hanoi 81
Dallas 59
Tokyo 49
São Paulo 46
New York 35
Cavallino 34
Rome 28
Buffalo 27
Helsinki 27
Frankfurt am Main 26
Catania 21
Haiphong 21
Orem 21
Minamishinagawa 20
Rio de Janeiro 18
Bengaluru 17
Chennai 17
Da Nang 17
Guangzhou 17
Messina 17
Mumbai 16
Warsaw 16
Amsterdam 14
Johannesburg 14
Montreal 14
Brasília 13
Naples 13
Vienna 13
Council Bluffs 12
Phoenix 12
Toronto 12
Boston 10
Campinas 10
Dhaka 10
Houston 10
Lappeenranta 10
Belo Horizonte 9
Denver 9
Dublin 9
Düsseldorf 9
Miami 9
Porto Alegre 9
Bergamo 8
Biên Hòa 8
Chicago 8
Curitiba 8
Milan 8
Thái Bình 8
Turin 8
Boardman 7
Bologna 7
Elk Grove Village 7
Guarulhos 7
Piscataway 7
Portsmouth 7
Tashkent 7
Buenos Aires 6
Bắc Ninh 6
Colorado Springs 6
Genoa 6
Hưng Yên 6
Hải Dương 6
Jakarta 6
Munich 6
Ninh Bình 6
Nuremberg 6
Paris 6
Philadelphia 6
Stockholm 6
Turku 6
Atlanta 5
Baghdad 5
Baltimore 5
City of London 5
Guayaquil 5
Hortolândia 5
Jeddah 5
João Pessoa 5
Kingston 5
Lahore 5
Manchester 5
Mexico City 5
Nairobi 5
New Delhi 5
Perugia 5
Riga 5
San Francisco 5
Santiago 5
Sorocaba 5
Totale 4.293
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Nome #
Rendicontazione delle attività svolte nell’anno 2022 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 114
Sensing B-amyloid with amphiphilic cyclodextrin/GO/KLVFF nanohybrid 113
Resoconto delle attività svolte nell’anno 2023 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 111
Functional modification of graphene nanoparticles: covalent grafting of peptides and π bonding for drug loading and delivery 98
Rendicontazione delle attività svolte nell’anno 2021 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 95
Probing the efficacy of peptide conjugates inhibitors against Ab aggregation 94
KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing 93
KLVFF@Amphiphilic Cyclodextrin/GO Nanohybrids for β-amyloid Sensing 92
KLVFF Functionalized Graphene Oxide for Aβ42 Peptide Electrical Detection: A Promising Nanomaterial for the Development of Alzheimer's Disease Diagnostic Devices 88
37th European Peptide Symposium-14th International Peptide Symposium 87
Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose-conjugated beta sheet breaker peptides 86
Memantine and amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice 85
An integrable sensoristic platform for β-amyloid based on supramolecular interactions 82
Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain 80
Understanding the interaction between amyloid-?-peptide (1-42) and its aggregation inhibitors: application of ESI and MALDI mass spectrometry 80
Cu(II) interaction with amylin's peptide fragments 78
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro 78
Cyclodextrin Nanomagnetes Decorated With Peptides: From Abeta-Amyloid Detection To Theranostic 78
A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction 77
Metal ion interactions within the 1-16 N-terminal region of ²-Amyloid 75
Monomers of beta-amyloid protein are endowed with neuroprotective activity 74
Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study 73
Spectroscopic studies of nitric oxide interaction with copper(II) complexes of prion protein bis-octarepeat fragments. 72
Copper(II) complexes of rat amylin fragments. 71
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment 70
Semax, an ACTH(4-10) peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity 68
New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway 67
Probing the Residual Structure in Avian Prion Hexarepeats by CD, NMR and MD Techniques 65
A carboxyethyl-β-cyclodextrin polymer and a defensin derived peptide complex with wound healing potential 64
The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment 64
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence 62
A Spectroscopic Study on the Amyloid‐β Interaction with Clicked Peptide‐Porphyrin Conjugates: a Vision Toward the Detection of Aβ Peptides in Aqueous Solution 62
Transition metal complexes of terminally protected peptides containing histidyl residues 61
A Metalloporphyrin-Peptide Conjugate as an Effective Inhibitor of Amyloid-beta Peptide Fibrillation and Cytotoxicity 61
Magnetic Nanoparticles tailored with Peptides/Amphiphilic Cyclodextrins assemblies: from Amyloid- detection to theranostic applications. 60
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies 60
Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life 59
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? 59
Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region 58
Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-[beta] Oligomer Formation and Cytotoxicity 58
New Conjugates of Hyaluronic Acid with γ-Cyclodextrin as Sorafenib Carrier in Cancer Cells 56
Designing trehalose-conjugated peptide inhibitors for the oligomerization and toxicity of Alzheimer s A² 55
Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study 55
Copper(II) and nickel(II) binding modes in a histidine-containing model dodecapeptide 55
Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles 54
The hydrolytic stability of the human tubulin α 1A protein fragment – a potential reason for the role of metal ions in the development of neurodegenerative diseases 51
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study 50
Effetti di nuove diketopiperazine in un modello in vivo di Degenerazione Maculare Senile 50
Iron accumulation and retinal pathology: neuroprotection by diketopiperazines 50
The N-terminal Peptide of the Three Human Isoforms of the Mitochondrial Voltage Dependent Anion Channel (hVDAC) Have Different Helical Propensity 49
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against A?(1-42)-induced toxicity 49
Interaction of copper(II) with the prion peptide fragment HuPrP(76-114) encompassing four histidyl residues within and outside the octarepeat domain 48
Small peptide conjugates for neuroprotection and Aβ detection 48
Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons 48
Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-? aggregation 47
Cyclodextrin Nanomagnetes Decorated With Peptides: From Aβ-Amyloid Detection To Theranostic 46
Neuroprotection and amyloid detection by small peptide conjugates 46
Coordination features of copper(II) complexes with human doppel protein fragments 45
Membrane Interactions and Conformational Preferences of Human and Avian Prion N-terminal tandem repeats: the role of copper(II) ions, pH, and membrane mimicking 45
Trehalose conjugated Beta-sheet breaker peptides as stabilizers of A-Beta monomers 45
Metal ion driven turn conformation in two histidine containing short peptides 44
beta-Amyloid Monomers Are Neuroprotective 44
Peptides-tailored Cyclodextrin Nanomagnets for Amyloid-b targeting 43
Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of A?(1-42) fibrillogenesis and toxicity 42
Copper(II) coordination properties of the integrin ligand sequence PHSRN and its new beta-cyclodextrin conjugates 42
KLVFF-PEG-tailored Cyclodextrin Nanomagnets as Novel Tools for beta-Amyloide Targeting 42
Zn(II) interaction with peptide fragments of beta-amyloid, 41
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases 41
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides 41
On the environmental factors affecting the structural and cytotoxic properties of IAPP peptides 40
Nanomagnets based on Peptides-decorated Cyclodextrin for Amyloid-beta targeting 40
The role of Cu(II) ions in the conformational preferences and membrane interaction of human and avian prion proteins N-terminal tandem repeat peptides 40
Bioinspired RGD-Functionalized Gold Nanoparticles for Integrin-Driven Interaction with Melanoma Cells 40
Corrigendum to: : Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-? Oligomer Formation and Cytotoxicity (ChemBioChem, (2016), 17, (1541-1549), 10.1002/cbic.201600243) 40
Designing trehalose-conjugated peptides for the inhibition of Alzheimer s Ab oligomerization and neurotoxicity. 40
Location of copper(II) within the PrP(106-126) fragment and influence of the metal ion on the conformational change of this peptide. 39
Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer film - Effects on fibroblast spreading 39
Coordination features of prion protein domains 38
Aggregation and cytotoxic properties of h-IAPP17-29 and r-IAPP17-29 fragments: a comparative study with the respective full length parent polypeptides 38
Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity 37
Functional mimics of Cu-Zn Superoxide Dismutase enzymes 37
Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity 37
Metal ions in neurodegeneration 36
Copper(II) binding of prion protein's octarepeat model peptides 36
Environmental effects on conformational diseases. Reactive oxygen species and membrane interactions with prion, amylin and their peptide fragments 34
Prion proteins leading to neurodegeneration 34
Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity. 33
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein 33
Cyclodextrin Polymers as Delivery Systems for Targeted Anti-Cancer Chemoth 33
Functionalizing cryogels with the GPGKLVFF peptide for amyloid-β binding: A comparative study of two synthetic pathways 33
Functional and structural characterization of the N_terminal peptide of the mitochondrial 32
Metal ions affect insulin-degrading enzyme activity 32
The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106-114 region of human prion protein. 32
Copper(II) Interaction with Unstructured Prion Domain Outside the Octarepeat Region: Speciation, Stability, and Binding Details of Copper(II) Complexes with PrP106-126 Peptides. 31
Studies on the metal binding affinity of histidyl residues inside and outside the octarepeat domain of prion protein. 30
Inside the PXXP motif. A combined NMR and CD study of hexapeptides belonging to the N-terminal domain of the chicken prion protein 30
Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer's disease on A?1-40 peptide early assembly 30
Aggregation properties of the peptide fragments derived from the 17-29 region of the human and rat IAPP: a comparative study with two new PEG-conjugated variants of the human sequence. 29
Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy 29
Environmental effects on a prion's helix II domain: Copper(II) and membrane interactions with PrP180-193 and its analogues 29
Totale 5.525
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Categoria #
all - tutte 23.974
article - articoli 15.840
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 653
Totale 40.467
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 7 0 19 3
2024/20252.748 37 17 194 103 457 153 46 206 76 232 674 553
2025/20264.379 256 395 430 728 797 209 642 218 227 253 145 79
2026/2027131 131 0 0 0 0 0 0 0 0 0 0 0
Totale 7.287