PAPPALARDO, GIUSEPPE
 Distribuzione geografica
Continente #
AS - Asia 3.551
NA - Nord America 2.564
EU - Europa 1.044
SA - Sud America 667
Continente sconosciuto - Info sul continente non disponibili 180
AF - Africa 73
OC - Oceania 5
Totale 8.084
Nazione #
US - Stati Uniti d'America 2.402
SG - Singapore 1.430
CN - Cina 859
BR - Brasile 513
VN - Vietnam 365
IT - Italia 362
HK - Hong Kong 349
FR - Francia 216
NL - Olanda 171
KR - Corea 152
JP - Giappone 75
BD - Bangladesh 74
CA - Canada 74
IN - India 73
DE - Germania 58
GB - Regno Unito 52
AR - Argentina 45
FI - Finlandia 44
ID - Indonesia 32
EC - Ecuador 31
MX - Messico 29
ZA - Sudafrica 29
IL - Israele 25
CO - Colombia 22
PL - Polonia 19
ES - Italia 18
CL - Cile 17
VE - Venezuela 17
JM - Giamaica 16
PK - Pakistan 16
AT - Austria 15
IQ - Iraq 12
SA - Arabia Saudita 12
CR - Costa Rica 11
IE - Irlanda 11
RU - Federazione Russa 11
UZ - Uzbekistan 11
PH - Filippine 10
UA - Ucraina 10
DZ - Algeria 9
PE - Perù 9
EG - Egitto 8
PY - Paraguay 8
MY - Malesia 7
MA - Marocco 6
SE - Svezia 6
TH - Thailandia 6
CH - Svizzera 5
DK - Danimarca 5
KE - Kenya 5
LB - Libano 5
LV - Lettonia 5
TR - Turchia 5
UY - Uruguay 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
AU - Australia 4
BE - Belgio 4
CZ - Repubblica Ceca 4
KH - Cambogia 4
TN - Tunisia 4
TT - Trinidad e Tobago 4
BY - Bielorussia 3
CY - Cipro 3
GT - Guatemala 3
HN - Honduras 3
LT - Lituania 3
NI - Nicaragua 3
NP - Nepal 3
RO - Romania 3
SV - El Salvador 3
BZ - Belize 2
CI - Costa d'Avorio 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GR - Grecia 2
HU - Ungheria 2
JO - Giordania 2
LK - Sri Lanka 2
MD - Moldavia 2
OM - Oman 2
PA - Panama 2
PR - Porto Rico 2
PT - Portogallo 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
AM - Armenia 1
AW - Aruba 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BH - Bahrain 1
BM - Bermuda 1
BS - Bahamas 1
CG - Congo 1
CU - Cuba 1
DJ - Gibuti 1
ET - Etiopia 1
GA - Gabon 1
GD - Grenada 1
Totale 7.886
Città #
Singapore 857
Santa Clara 518
Hefei 344
Hong Kong 341
San Jose 294
Ashburn 246
Lauterbourg 168
Seoul 149
Ho Chi Minh City 133
Beijing 130
Los Angeles 129
Hanoi 82
Dallas 65
Tokyo 49
São Paulo 46
New York 39
Cavallino 34
Rome 30
Buffalo 29
Helsinki 27
Frankfurt am Main 26
Catania 22
Haiphong 21
Naples 21
Orem 21
Council Bluffs 20
Minamishinagawa 20
Bengaluru 18
Houston 18
Montreal 18
Phoenix 18
Rio de Janeiro 18
Chennai 17
Da Nang 17
Guangzhou 17
Messina 17
Milan 17
Mumbai 16
Warsaw 16
Chicago 15
Miami 15
Toronto 15
Amsterdam 14
Johannesburg 14
Brasília 13
Brooklyn 13
Vienna 13
Philadelphia 12
Atlanta 11
Boston 11
Denver 11
Dhaka 11
Belo Horizonte 10
Campinas 10
Curitiba 10
Dublin 10
Lappeenranta 10
Bogotá 9
Bologna 9
Düsseldorf 9
Guayaquil 9
Las Vegas 9
Piscataway 9
Porto Alegre 9
Portsmouth 9
Turin 9
Bergamo 8
Biên Hòa 8
Kingston 8
Queens 8
Quito 8
Thái Bình 8
Baltimore 7
Boardman 7
Buenos Aires 7
Elk Grove Village 7
Genoa 7
Guarulhos 7
San José 7
Tashkent 7
Bắc Ninh 6
Colorado Springs 6
Columbus 6
Florence 6
Hưng Yên 6
Hải Dương 6
Jakarta 6
Munich 6
Newark 6
Ninh Bình 6
Nuremberg 6
Paris 6
San Antonio 6
Stockholm 6
Turku 6
Baghdad 5
Charlotte 5
City of London 5
Hortolândia 5
Jeddah 5
Totale 4.586
Nome #
Resoconto delle attività svolte nell’anno 2023 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 122
Sensing B-amyloid with amphiphilic cyclodextrin/GO/KLVFF nanohybrid 120
Rendicontazione delle attività svolte nell’anno 2022 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 119
Functional modification of graphene nanoparticles: covalent grafting of peptides and π bonding for drug loading and delivery 102
KLVFF oligopeptide-decorated amphiphilic cyclodextrin nanomagnets for selective amyloid beta recognition and fishing 102
Rendicontazione delle attività svolte nell’anno 2021 dall’Unità Dipartimentale di Valorizzazione della Ricerca del DSCTM- CNR 102
Probing the efficacy of peptide conjugates inhibitors against Ab aggregation 98
KLVFF@Amphiphilic Cyclodextrin/GO Nanohybrids for β-amyloid Sensing 98
37th European Peptide Symposium-14th International Peptide Symposium 95
Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain 92
KLVFF Functionalized Graphene Oxide for Aβ42 Peptide Electrical Detection: A Promising Nanomaterial for the Development of Alzheimer's Disease Diagnostic Devices 92
Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose-conjugated beta sheet breaker peptides 91
Understanding the interaction between amyloid-?-peptide (1-42) and its aggregation inhibitors: application of ESI and MALDI mass spectrometry 88
Memantine and amantadine KLVFF peptide conjugates: Synthesis, structure determination, amyloid-β interaction and effects on recognition memory in mice 88
An integrable sensoristic platform for β-amyloid based on supramolecular interactions 88
A zinc–porphyrin–peptide conjugate via “click-chemistry”: synthesis and amyloid-β interaction 87
Novel Peptide-Calix[4]arene Conjugate Inhibits Aβ Aggregation and Rescues Neurons from Aβ's Oligomers Cytotoxicity in Vitro 86
Cyclodextrin Nanomagnetes Decorated With Peptides: From Abeta-Amyloid Detection To Theranostic 84
Cu(II) interaction with amylin's peptide fragments 82
Copper(II) Coordination Abilities of the Tau Protein's N-Terminus Peptide Fragments: A Combined Potentiometric, Spectroscopic and Mass Spectrometric Study 82
Aβ8-20 Fragment as an Anti-Fibrillogenic and Neuroprotective Agent: Advancing toward Efficient Alzheimer’s Disease Treatment 78
Metal ion interactions within the 1-16 N-terminal region of ²-Amyloid 77
Monomers of beta-amyloid protein are endowed with neuroprotective activity 76
Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons 75
Spectroscopic studies of nitric oxide interaction with copper(II) complexes of prion protein bis-octarepeat fragments. 74
Copper(II) complexes of rat amylin fragments. 74
The A?8-20 fragment as anti-fibrillogenic and neuroprotective agent: advancing towards efficient Alzheimer's disease treatment 74
New comprehensive studies of a gold(III) Dithiocarbamate complex with. proven anticancer properties: Aqueous dissolution with cyclodextrins, pharmacokinetics and upstream inhibition of the ubiquitin-proteasome pathway 73
Semax, an ACTH(4-10) peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity 73
A Metalloporphyrin-Peptide Conjugate as an Effective Inhibitor of Amyloid-beta Peptide Fibrillation and Cytotoxicity 72
Tau/A beta chimera peptides: Evaluating the dual function of metal coordination and membrane interaction in one sequence 72
Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-[beta] Oligomer Formation and Cytotoxicity 71
A carboxyethyl-β-cyclodextrin polymer and a defensin derived peptide complex with wound healing potential 70
A? and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer's Disease? 70
Probing the Residual Structure in Avian Prion Hexarepeats by CD, NMR and MD Techniques 68
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies 68
Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life 67
Magnetic Nanoparticles tailored with Peptides/Amphiphilic Cyclodextrins assemblies: from Amyloid- detection to theranostic applications. 66
A Spectroscopic Study on the Amyloid‐β Interaction with Clicked Peptide‐Porphyrin Conjugates: a Vision Toward the Detection of Aβ Peptides in Aqueous Solution 66
Copper (II) binding properties of an octapeptide fragment from the R3 region of tau protein: A combined potentiometric, spectroscopic and mass spectrometric study 65
Transition metal complexes of terminally protected peptides containing histidyl residues 64
Copper(II) and nickel(II) binding modes in a histidine-containing model dodecapeptide 61
Tau/Aβ chimera peptides: A Thioflavin-T and MALDI-TOF study of Aβ amyloidosis in the presence of Cu(II) or Zn(II) ions and total lipid brain extract (TLBE) vesicles 61
New Conjugates of Hyaluronic Acid with γ-Cyclodextrin as Sorafenib Carrier in Cancer Cells 61
Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region 60
Effetti di nuove diketopiperazine in un modello in vivo di Degenerazione Maculare Senile 58
Designing trehalose-conjugated peptide inhibitors for the oligomerization and toxicity of Alzheimer s A² 56
The hydrolytic stability of the human tubulin α 1A protein fragment – a potential reason for the role of metal ions in the development of neurodegenerative diseases 56
Iron accumulation and retinal pathology: neuroprotection by diketopiperazines 56
Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-? aggregation 54
Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study 54
Interaction of copper(II) with the prion peptide fragment HuPrP(76-114) encompassing four histidyl residues within and outside the octarepeat domain 53
Small peptide conjugates for neuroprotection and Aβ detection 53
On the environmental factors affecting the structural and cytotoxic properties of IAPP peptides 52
The N-terminal Peptide of the Three Human Isoforms of the Mitochondrial Voltage Dependent Anion Channel (hVDAC) Have Different Helical Propensity 52
Cyclodextrin Nanomagnetes Decorated With Peptides: From Aβ-Amyloid Detection To Theranostic 52
Neuroprotection and amyloid detection by small peptide conjugates 52
Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against A?(1-42)-induced toxicity 51
Membrane Interactions and Conformational Preferences of Human and Avian Prion N-terminal tandem repeats: the role of copper(II) ions, pH, and membrane mimicking 50
Metal ion driven turn conformation in two histidine containing short peptides 49
beta-Amyloid Monomers Are Neuroprotective 49
Copper(II) coordination properties of the integrin ligand sequence PHSRN and its new beta-cyclodextrin conjugates 48
Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases 48
Coordination features of copper(II) complexes with human doppel protein fragments 47
Trehalose conjugated Beta-sheet breaker peptides as stabilizers of A-Beta monomers 47
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides 47
Design and synthesis of new trehalose-conjugated pentapeptides as inhibitors of A?(1-42) fibrillogenesis and toxicity 46
KLVFF-PEG-tailored Cyclodextrin Nanomagnets as Novel Tools for beta-Amyloide Targeting 46
Corrigendum to: : Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-? Oligomer Formation and Cytotoxicity (ChemBioChem, (2016), 17, (1541-1549), 10.1002/cbic.201600243) 46
Peptides-tailored Cyclodextrin Nanomagnets for Amyloid-b targeting 46
Location of copper(II) within the PrP(106-126) fragment and influence of the metal ion on the conformational change of this peptide. 45
Bioinspired RGD-Functionalized Gold Nanoparticles for Integrin-Driven Interaction with Melanoma Cells 45
Nanomagnets based on Peptides-decorated Cyclodextrin for Amyloid-beta targeting 44
Zn(II) interaction with peptide fragments of beta-amyloid, 43
Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer film - Effects on fibroblast spreading 42
The role of Cu(II) ions in the conformational preferences and membrane interaction of human and avian prion proteins N-terminal tandem repeat peptides 42
Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity 42
Designing trehalose-conjugated peptides for the inhibition of Alzheimer s Ab oligomerization and neurotoxicity. 42
Cyclodextrin Polymers as Delivery Systems for Targeted Anti-Cancer Chemoth 41
Aggregation and cytotoxic properties of h-IAPP17-29 and r-IAPP17-29 fragments: a comparative study with the respective full length parent polypeptides 41
Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity 40
Coordination features of prion protein domains 40
Environmental effects on conformational diseases. Reactive oxygen species and membrane interactions with prion, amylin and their peptide fragments 39
Functional mimics of Cu-Zn Superoxide Dismutase enzymes 39
The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106-114 region of human prion protein. 39
Functionalizing cryogels with the GPGKLVFF peptide for amyloid-β binding: A comparative study of two synthetic pathways 38
Metal ions in neurodegeneration 38
Copper(II) Interaction with Unstructured Prion Domain Outside the Octarepeat Region: Speciation, Stability, and Binding Details of Copper(II) Complexes with PrP106-126 Peptides. 37
Copper(II) binding of prion protein's octarepeat model peptides 37
Prion proteins leading to neurodegeneration 36
Cyclodextrin polymers decorated with RGD peptide as delivery systems for targeted anti-cancer chemotherapy 35
Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity. 34
Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein 34
Functional and structural characterization of the N_terminal peptide of the mitochondrial 34
Studies on the metal binding affinity of histidyl residues inside and outside the octarepeat domain of prion protein. 34
The effect of non-coordinating side chains on the metal binding affinities of peptides of histidine 33
Environmental effects on a prion's helix II domain: Copper(II) and membrane interactions with PrP180-193 and its analogues 33
Inside the PXXP motif. A combined NMR and CD study of hexapeptides belonging to the N-terminal domain of the chicken prion protein 33
Metal ions affect insulin-degrading enzyme activity 33
Ion mobility spectrometry combined with multivariate statistical analysis: revealing the effects of a drug candidate for Alzheimer's disease on A?1-40 peptide early assembly 33
Totale 6.068
Categoria #
all - tutte 27.004
article - articoli 17.918
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 738
Totale 45.660


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202429 0 0 0 0 0 0 0 0 7 0 19 3
2024/20252.748 37 17 194 103 457 153 46 206 76 232 674 553
2025/20264.379 256 395 430 728 797 209 642 218 227 253 145 79
2026/2027928 250 273 405 0 0 0 0 0 0 0 0 0
Totale 8.084