CNR Institutional Research Information System

COLOTTI, GIANNI
 Distribuzione geografica
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Continente #
AS - Asia 2.772
NA - Nord America 1.557
EU - Europa 781
SA - Sud America 557
Continente sconosciuto - Info sul continente non disponibili 148
AF - Africa 55
OC - Oceania 5
Totale 5.875
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Nazione #
US - Stati Uniti d'America 1.484
SG - Singapore 1.156
CN - Cina 580
BR - Brasile 446
HK - Hong Kong 344
VN - Vietnam 291
IT - Italia 261
FR - Francia 154
NL - Olanda 90
BD - Bangladesh 81
KR - Corea 63
DE - Germania 56
IN - India 56
JP - Giappone 56
GB - Regno Unito 52
AR - Argentina 45
CA - Canada 36
FI - Finlandia 35
EC - Ecuador 18
ID - Indonesia 18
TR - Turchia 18
ES - Italia 16
MX - Messico 15
ZA - Sudafrica 12
IQ - Iraq 11
SA - Arabia Saudita 11
EG - Egitto 10
IE - Irlanda 10
PE - Perù 10
PL - Polonia 10
UZ - Uzbekistan 10
PK - Pakistan 9
PY - Paraguay 9
IL - Israele 8
PH - Filippine 8
SE - Svezia 8
AT - Austria 7
CH - Svizzera 7
CL - Cile 7
EE - Estonia 7
MA - Marocco 7
NP - Nepal 7
UA - Ucraina 7
VE - Venezuela 7
CO - Colombia 6
MY - Malesia 6
RU - Federazione Russa 6
UY - Uruguay 6
AE - Emirati Arabi Uniti 5
HU - Ungheria 5
KE - Kenya 5
LT - Lituania 5
AZ - Azerbaigian 4
BE - Belgio 4
DO - Repubblica Dominicana 4
JO - Giordania 4
KZ - Kazakistan 4
LV - Lettonia 4
RO - Romania 4
TH - Thailandia 4
BG - Bulgaria 3
BO - Bolivia 3
DZ - Algeria 3
ET - Etiopia 3
GR - Grecia 3
LK - Sri Lanka 3
NI - Nicaragua 3
PT - Portogallo 3
RS - Serbia 3
TT - Trinidad e Tobago 3
AL - Albania 2
AU - Australia 2
BS - Bahamas 2
BY - Bielorussia 2
CR - Costa Rica 2
CZ - Repubblica Ceca 2
GT - Guatemala 2
HN - Honduras 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MD - Moldavia 2
MT - Malta 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
OM - Oman 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
TW - Taiwan 2
UG - Uganda 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BH - Bahrain 1
BM - Bermuda 1
BW - Botswana 1
BZ - Belize 1
CD - Congo 1
CM - Camerun 1
CW - ???statistics.table.value.countryCode.CW??? 1
Totale 5.709
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Città #
Singapore 666
Santa Clara 405
Hong Kong 338
San Jose 164
Hefei 148
Ashburn 140
Beijing 125
Lauterbourg 110
Ho Chi Minh City 107
Rome 79
Los Angeles 73
Hanoi 71
Seoul 60
New York 48
São Paulo 46
Tokyo 44
Dallas 37
Frankfurt am Main 29
Da Nang 23
Milan 23
Buffalo 22
Lappeenranta 18
Rio de Janeiro 16
Amsterdam 14
Bengaluru 14
Brooklyn 13
Helsinki 13
Naples 13
Orem 12
Boardman 11
Campinas 11
Council Bluffs 11
London 11
Chennai 10
Düsseldorf 10
Atlanta 9
Chicago 9
Dublin 9
Haiphong 9
Johannesburg 9
Minamishinagawa 9
Montreal 9
Tashkent 9
Marigliano 8
Nuremberg 8
Riyadh 8
San Francisco 8
Stockholm 8
Thái Bình 8
Istanbul 7
Porto Alegre 7
Portsmouth 7
Belo Horizonte 6
Brasília 6
Damanhur 6
Denver 6
Florence 6
Guarulhos 6
Kathmandu 6
Manchester 6
Quito 6
San Antonio 6
São Bernardo do Campo 6
Toronto 6
Warsaw 6
Zurich 6
Ankara 5
Curitiba 5
Fayetteville 5
Jakarta 5
Kyiv 5
Miami 5
Mumbai 5
Phoenix 5
Poplar 5
Salvador 5
São José do Rio Preto 5
Amman 4
Boston 4
Buenos Aires 4
Columbiana 4
Delhi 4
Dhaka 4
Guangzhou 4
Ha Long 4
Hyderabad 4
Hải Dương 4
Jaú 4
Las Vegas 4
Latina 4
Lima 4
Madrid 4
Manaus 4
Manila 4
Nairobi 4
Philadelphia 4
Pisa 4
Quảng Ngãi 4
Quận Một 4
Recife 4
Totale 3.307
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Nome #
Widespread in vivo efficacy of The-0504: A conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers. 109
Applying Quality principles and Project Management methodologies in biomedical research: a public research network's case study. 104
EGF receptor in organ development, tissue homeostasis and regeneration 102
Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules 102
Bcl-2 family inhibitors sensitize human cancer models to therapy 101
Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. 85
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 85
A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories 85
AI is a viable alternative to high throughput screening: a 318-target study 83
Applying Design of Experiment methodology to PEI toxicity assay on neural progenitor cells 78
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 77
Quality-based model for Life Sciences research guidelines 75
Two different crystal forms of sorcin, a penta-EF-hand Ca2+-binding protein 70
A validated Quality Management System for a research lab 70
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming 70
Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1 69
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate 69
The qPMO project: applying Quality principles and methodologies in Life Sciences research 68
MarLab: a marine research laboratory organized according to a quality management system 67
"An innovative Quality-based model for drafting scientific guidelines" 66
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach 66
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 65
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design 65
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 65
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability 65
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin 62
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex. 61
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 61
GOLPH3 Is Essential for Contractile Ring Formation and Rab11 Localization to the Cleavage Site during Cytokinesis in Drosophila melanogaster 61
ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds 61
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster. 60
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 59
A Small-Molecule Targeting the MicroRNA Binding Domain of Argonaute 2 improves the Retinoic Acid Differentiation Response of the Acute Promyelocytic Leukemia Cell Line NB4 57
A first-in-class non-cytotoxic nanocarrier based on a recombinant human ferritin boosts targeted therapy, chemotherapy and immunotherapy 57
Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands 56
Selective delivery of doxorubicin by novel stimuli-sensitive nano-ferritins overcomes tumor refractoriness 56
Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. 56
Certificazione UNI EN ISO 9001:2008 di un laboratorio di ricerca (certificato n. 585SGQ00) 53
Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing. A study with site-specific mutants 53
Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis 51
Help4Lab: Software Modulare per gestire Qualità, Sicurezza, Ambiente e Documenti in un laboratorio di ricerca 51
The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3 51
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells 50
The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor. 49
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 48
The optimization of a laboratory protocol through Design of Experiment statistical methodology 47
Quality4lab 47
The qPMO network: quality management tools to improve research efficiency, reproducibility, data management and dissemination 46
Metal regulation of siderophore synthesis in Pseudomonas aeruginosa and functional effects of siderophore-metal complexes. 46
The optimization of a laboratory protocol through Design of Experiment statistical methodology 46
Small Molecules Targeting the miRNA-Binding Domain of Argonaute 2: From Computer-Aided Molecular Design to RNA Immunoprecipitation. 46
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 46
Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B 46
The qPMO network: quality management tools to improve research efficiency, reproducibility, data management and dissemination 45
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target 45
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity 44
. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs. 43
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 43
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity. 43
Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains 43
Cooperativity and Ligand-linked Polymerisation in Scapharca Tetrameric Haemoglobin. 42
Drug delivery using protein nanocarriers: human or virus templates? 42
Use of ferritin-based metal-encapsulated nanocarriers as anticancer agents 42
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects 41
protein nanocarriers for drug delivery 41
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 41
FMEA analysis on a "pilot process" to validate aptamers as therapeutic purposes 41
Metals and metal derivatives in medicine 39
Identification of the site of ferrocyanide binding involved in the intramolecular electron transfer process to oxidized heme in Scapharca dimeric hemoglobin. 39
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 38
Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding 38
Sorcin 38
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 38
Halothane does not alter Ca2+ affinity of troponin C 38
Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system. 37
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 37
The crystal structure of the sorcin calcium binding domain provides a model of Ca2+-dependent processes in the full-length protein 37
Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis 36
Complex modulation of L-type Ca(2+) current inactivation by sorcin in isolated rabbit cardiomyocytes. 35
N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy 35
The homodimeric hemoglobin from Scapharca can be locked into new cooperative structures upon reaction of Cys92, located at the subunit interface, with organomercurials. 35
Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis 33
Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells 33
The X-ray structure of trypanothione reductase in complex with NADPH and Sb(III) discloses the molecular basis of antimony treatment in leishmaniasis 33
Sorcin modulates cardiac L-type Ca(2+) current by functional interaction with the alpha(1C) subunit in rabbits 33
The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization 31
Sauron is the Drosophila orthologue of the oncogene GOLPH3 31
L-type calcium current is modulated by sorcin in rabbit ventricular myocytes 30
The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells 30
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism 30
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming 29
What is the future of the CNR? 29
Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation 29
Polyamine metabolism in Leishmania: from arginine to trypanothione 29
Applying Design of Experiments methodology to PEI toxicity assay on neural progenitor cells. 29
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. 29
The desaturase from Bacillus subtilis a promising tool for the selective olefination of phospholipids. 28
The central role of gut microbiota in drug metabolism and personalized medicine 28
Standardization in Life-science Research - Making the Case for Harmonization to Improve Communication and Sharing of Data amongst Researchers 28
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 28
Totale 5.130
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Categoria #
all - tutte 21.132
article - articoli 17.813
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 991
Totale 39.936
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202425 0 0 0 0 0 0 0 1 7 1 9 7
2024/20252.081 9 13 178 77 364 135 69 151 109 154 451 371
2025/20263.540 146 292 314 515 682 149 471 212 216 255 112 176
2026/2027229 229 0 0 0 0 0 0 0 0 0 0 0
Totale 5.875