CNR Institutional Research Information System

COLOTTI, GIANNI
 Distribuzione geografica
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Continente #
AS - Asia 2.707
NA - Nord America 1.281
EU - Europa 722
SA - Sud America 547
AF - Africa 54
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.317
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Nazione #
US - Stati Uniti d'America 1.228
SG - Singapore 1.156
CN - Cina 579
BR - Brasile 442
HK - Hong Kong 342
VN - Vietnam 289
IT - Italia 210
FR - Francia 154
NL - Olanda 89
KR - Corea 63
DE - Germania 56
JP - Giappone 56
IN - India 55
GB - Regno Unito 50
AR - Argentina 43
FI - Finlandia 35
BD - Bangladesh 26
CA - Canada 24
EC - Ecuador 18
ID - Indonesia 18
TR - Turchia 18
ES - Italia 13
MX - Messico 13
ZA - Sudafrica 12
IQ - Iraq 11
SA - Arabia Saudita 11
EG - Egitto 10
IE - Irlanda 10
PE - Perù 10
PL - Polonia 10
UZ - Uzbekistan 10
PK - Pakistan 9
PY - Paraguay 9
IL - Israele 8
PH - Filippine 8
SE - Svezia 8
AT - Austria 7
CH - Svizzera 7
EE - Estonia 7
MA - Marocco 7
UA - Ucraina 7
CL - Cile 6
MY - Malesia 6
RU - Federazione Russa 6
UY - Uruguay 6
VE - Venezuela 6
AE - Emirati Arabi Uniti 5
HU - Ungheria 5
KE - Kenya 5
LT - Lituania 5
AZ - Azerbaigian 4
BE - Belgio 4
CO - Colombia 4
DO - Repubblica Dominicana 4
JO - Giordania 4
KZ - Kazakistan 4
LV - Lettonia 4
NP - Nepal 4
RO - Romania 4
BG - Bulgaria 3
BO - Bolivia 3
DZ - Algeria 3
ET - Etiopia 3
GR - Grecia 3
LK - Sri Lanka 3
TH - Thailandia 3
TT - Trinidad e Tobago 3
AL - Albania 2
AU - Australia 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
GT - Guatemala 2
KG - Kirghizistan 2
LU - Lussemburgo 2
MD - Moldavia 2
MT - Malta 2
NI - Nicaragua 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PT - Portogallo 2
RS - Serbia 2
SI - Slovenia 2
SK - Slovacchia (Repubblica Slovacca) 2
TN - Tunisia 2
TW - Taiwan 2
UG - Uganda 2
AM - Armenia 1
AO - Angola 1
BB - Barbados 1
BH - Bahrain 1
BM - Bermuda 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
CM - Camerun 1
CR - Costa Rica 1
CW - ???statistics.table.value.countryCode.CW??? 1
CY - Cipro 1
DK - Danimarca 1
Totale 5.301
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Città #
Singapore 666
Santa Clara 388
Hong Kong 338
San Jose 159
Hefei 148
Beijing 125
Lauterbourg 110
Ho Chi Minh City 107
Ashburn 92
Rome 79
Hanoi 69
Los Angeles 64
Seoul 60
São Paulo 45
Tokyo 44
New York 40
Dallas 35
Frankfurt am Main 29
Da Nang 23
Lappeenranta 18
Rio de Janeiro 16
Buffalo 15
Amsterdam 14
Bengaluru 14
Milan 14
Helsinki 13
Naples 13
Brooklyn 12
Council Bluffs 11
Orem 11
Chennai 10
Düsseldorf 10
London 10
Campinas 9
Dublin 9
Haiphong 9
Johannesburg 9
Minamishinagawa 9
Montreal 9
Tashkent 9
Marigliano 8
Nuremberg 8
Riyadh 8
San Francisco 8
Stockholm 8
Thái Bình 8
Atlanta 7
Istanbul 7
Porto Alegre 7
Belo Horizonte 6
Boardman 6
Brasília 6
Damanhur 6
Denver 6
Guarulhos 6
Portsmouth 6
Quito 6
São Bernardo do Campo 6
Warsaw 6
Zurich 6
Ankara 5
Curitiba 5
Florence 5
Jakarta 5
Kyiv 5
Manchester 5
Mumbai 5
Poplar 5
Salvador 5
São José do Rio Preto 5
Amman 4
Boston 4
Buenos Aires 4
Chicago 4
Delhi 4
Dhaka 4
Guangzhou 4
Ha Long 4
Hyderabad 4
Hải Dương 4
Jaú 4
Latina 4
Lima 4
Manaus 4
Manila 4
Nairobi 4
Phoenix 4
Pisa 4
Quảng Ngãi 4
Quận Một 4
Recife 4
Riga 4
Toronto 4
Addis Ababa 3
Almaty 3
Asunción 3
Baghdad 3
Baku 3
Bangkok 3
Bologna 3
Totale 3.163
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Nome #
Widespread in vivo efficacy of The-0504: A conditionally-activatable nanoferritin for tumor-agnostic targeting of CD71-expressing cancers. 106
Applying Quality principles and Project Management methodologies in biomedical research: a public research network's case study. 102
Bcl-2 family inhibitors sensitize human cancer models to therapy 96
EGF receptor in organ development, tissue homeostasis and regeneration 96
Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules 93
Molecular basis for the impaired function of the natural F112L sorcin mutant: X-ray crystal structure, calcium affinity, and interaction with annexin VII and the ryanodine receptor. 84
A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories 84
Applying Design of Experiment methodology to PEI toxicity assay on neural progenitor cells 73
Quality-based model for Life Sciences research guidelines 72
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance 71
Two different crystal forms of sorcin, a penta-EF-hand Ca2+-binding protein 69
Doxorubicin and other anthracyclines in cancers: Activity, chemoresistance and its overcoming 68
The qPMO project: applying Quality principles and methodologies in Life Sciences research 66
AI is a viable alternative to high throughput screening: a 318-target study 66
Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1 65
"An innovative Quality-based model for drafting scientific guidelines" 63
A validated Quality Management System for a research lab 63
Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate 63
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases 63
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex. 61
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability 60
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site 59
MarLab: a marine research laboratory organized according to a quality management system 59
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach 59
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design 58
A Small-Molecule Targeting the MicroRNA Binding Domain of Argonaute 2 improves the Retinoic Acid Differentiation Response of the Acute Promyelocytic Leukemia Cell Line NB4 57
Sorcin promotes migration in cancer and regulates the EGF-dependent EGFR signaling pathways 57
GOLPH3 Is Essential for Contractile Ring Formation and Rab11 Localization to the Cleavage Site during Cytokinesis in Drosophila melanogaster 56
Huntingtin Ubiquitination Mechanisms and Novel Possible Therapies to Decrease the Toxic Effects of Mutated Huntingtin 55
PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster. 54
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome 54
Investigation of the Entry Pathway and Molecular Nature of sigma 1 Receptor Ligands 54
Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. 54
Selective delivery of doxorubicin by novel stimuli-sensitive nano-ferritins overcomes tumor refractoriness 53
ESI MS Studies of T. Brucei Trypanothione Reductase and its Reactions With Selected Metal Compounds 52
A first-in-class non-cytotoxic nanocarrier based on a recombinant human ferritin boosts targeted therapy, chemotherapy and immunotherapy 51
The multiple cellular functions of the oncoprotein Golgi phoshoprotein 3 51
Information transfer in the penta-EF-hand protein sorcin does not operate via the canonical structural/functional pairing. A study with site-specific mutants 50
Certificazione UNI EN ISO 9001:2008 di un laboratorio di ricerca (certificato n. 585SGQ00) 49
Help4Lab: Software Modulare per gestire Qualità, Sicurezza, Ambiente e Documenti in un laboratorio di ricerca 48
Known drugs identified by structure-based virtual screening are able to bind sigma-1 receptor and increase growth of huntington disease patient-derived cells 47
The optimization of a laboratory protocol through Design of Experiment statistical methodology 46
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells 46
Quality4lab 46
The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor. 46
Metal regulation of siderophore synthesis in Pseudomonas aeruginosa and functional effects of siderophore-metal complexes. 45
The qPMO network: quality management tools to improve research efficiency, reproducibility, data management and dissemination 45
Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B 45
The qPMO network: quality management tools to improve research efficiency, reproducibility, data management and dissemination 44
The optimization of a laboratory protocol through Design of Experiment statistical methodology 44
Small Molecules Targeting the miRNA-Binding Domain of Argonaute 2: From Computer-Aided Molecular Design to RNA Immunoprecipitation. 43
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases 42
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target 42
. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs. 41
Structural basis of ubiquitination mediated by protein splicing in early Eukarya 41
The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity. 41
Drug delivery using protein nanocarriers: human or virus templates? 41
The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity 40
Use of ferritin-based metal-encapsulated nanocarriers as anticancer agents 40
Cooperativity and Ligand-linked Polymerisation in Scapharca Tetrameric Haemoglobin. 39
Bioinformatics analysis of Ras homologue enriched in the striatum, a potential target for Huntington's disease therapy 39
FMEA analysis on a "pilot process" to validate aptamers as therapeutic purposes 39
Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains 39
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors 38
protein nanocarriers for drug delivery 38
Sorcin 38
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects 37
Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding 37
Identification of the site of ferrocyanide binding involved in the intramolecular electron transfer process to oxidized heme in Scapharca dimeric hemoglobin. 37
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis 36
Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents 36
Structure-function relationships in sorcin, a member of the penta EF-hand family. Interaction of sorcin fragments with the ryanodine receptor and an Escherichia coli model system. 35
Halothane does not alter Ca2+ affinity of troponin C 35
Metals and metal derivatives in medicine 34
Complex modulation of L-type Ca(2+) current inactivation by sorcin in isolated rabbit cardiomyocytes. 34
The homodimeric hemoglobin from Scapharca can be locked into new cooperative structures upon reaction of Cys92, located at the subunit interface, with organomercurials. 34
The crystal structure of the sorcin calcium binding domain provides a model of Ca2+-dependent processes in the full-length protein 33
Sorcin Links Calcium Signaling to Vesicle Trafficking, Regulates Polo-Like Kinase 1 and Is Necessary for Mitosis 32
N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy 32
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 31
Sorcin, a Calcium Binding Protein Involved in the Multidrug Resistance Mechanisms in Cancer Cells 31
Sauron is the Drosophila orthologue of the oncogene GOLPH3 31
The X-ray structure of trypanothione reductase in complex with NADPH and Sb(III) discloses the molecular basis of antimony treatment in leishmaniasis 30
Sorcin modulates cardiac L-type Ca(2+) current by functional interaction with the alpha(1C) subunit in rabbits 30
The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization 29
What is the future of the CNR? 29
Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis 29
The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells 29
Taxanes in cancer treatment: Activity, chemoresistance and its overcoming 28
Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation 28
The desaturase from Bacillus subtilis a promising tool for the selective olefination of phospholipids. 28
Applying Design of Experiments methodology to PEI toxicity assay on neural progenitor cells. 28
Standardization in Life-science Research - Making the Case for Harmonization to Improve Communication and Sharing of Data amongst Researchers 28
L-type calcium current is modulated by sorcin in rabbit ventricular myocytes 27
Polyamine metabolism in Leishmania: from arginine to trypanothione 27
The central role of gut microbiota in drug metabolism and personalized medicine 27
Antimony-Based Therapy of Leishmaniases, Molecular and Cellular Rationale. 27
New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism 26
Ligand-linked changes at the subunit interfaces in scapharca hemoglobins probed through the sulfhydryl infrared absorption 26
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives 26
Totale 4.756
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Categoria #
all - tutte 18.882
article - articoli 15.889
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 904
Totale 35.675
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202425 0 0 0 0 0 0 0 1 7 1 9 7
2024/20252.081 9 13 178 77 364 135 69 151 109 154 451 371
2025/20263.360 146 292 314 515 682 149 471 212 216 255 108 0
Totale 5.466