Background: Cardiomyocyte apoptosis increases in heart failure (HF) and is implicated in disease progression. The apoptotic cell is not inevitably committed to death, and appropriate therapy like left ventricular assist device (LVAD) support could offer a rescue of cellular functions. Literature data regarding the modulation of the apoptotic process during LVAD support are still controversial.
Cardiac molecular markers of programmed cell death are activated in end-stage heart failure patients supported by left ventricular assist device
Prescimone Tommaso;Caruso Raffaele;Cabiati Manuela;Caselli Chiara;Verde Alessandro;Del Ry Silvia;Giannessi Daniela
2014
Abstract
Background: Cardiomyocyte apoptosis increases in heart failure (HF) and is implicated in disease progression. The apoptotic cell is not inevitably committed to death, and appropriate therapy like left ventricular assist device (LVAD) support could offer a rescue of cellular functions. Literature data regarding the modulation of the apoptotic process during LVAD support are still controversial.File in questo prodotto:
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