The aim of this study is to determine if MSH2, a well known partner of BRCA1 involved in DNA repair, may contribute to breast and ovarian cancer development and progression.

BRCA1 interacts with several proteins implicated in homologous and non homologous recombination and in mismatch repair.

MSH2 role in BRCA1-driMSH2role inBRCA1-driven tumorigenesis: A preliminary study inyeast and in human tumors fromBRCA1-VUS carriers

Cervelli Tiziana;Galli Alvaro;
2015

Abstract

BRCA1 interacts with several proteins implicated in homologous and non homologous recombination and in mismatch repair.
2015
Istituto di Fisiologia Clinica - IFC
The aim of this study is to determine if MSH2, a well known partner of BRCA1 involved in DNA repair, may contribute to breast and ovarian cancer development and progression.
BRCA1
MSH2
Hereditary breast and ovarian cancer
Yeast functional assay
Mutational analysis
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Descrizione: MSH2role inBRCA1-driven tumorigenesis: A preliminary study inyeast and in human tumors fromBRCA1-VUS carriers
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/341291
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