BACKGROUND WHO/FAO defined probiotics as “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host” 1. The International Scientific Association for Prebiotics and Probiotics pointed out that most probiotic strains share “core benefits” linked to their metabolic activities, antimicrobial and immunomodulatory properties2. Despite being marketed for their activities, probiotics are currently commercialized as “number of live cells” and there are no other quality parameters to guarantee the functionality of the products. AIM Developing laboratory protocols suitable to evaluate the functional activity of commercialized probiotics. In particular, the barrier effect of the samples will be investigated testing their antimicrobial activity against the principal pathogens of the gastrointestinal tract (Escherichia coli ETEC H10407, Salmonella choleraesuis serovar typhimurium, Yersenia enterocolitica).
Protocols for functional fingerprinting of probiotics
Loris Pinto;Federico Baruzzi;
2024
Abstract
BACKGROUND WHO/FAO defined probiotics as “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host” 1. The International Scientific Association for Prebiotics and Probiotics pointed out that most probiotic strains share “core benefits” linked to their metabolic activities, antimicrobial and immunomodulatory properties2. Despite being marketed for their activities, probiotics are currently commercialized as “number of live cells” and there are no other quality parameters to guarantee the functionality of the products. AIM Developing laboratory protocols suitable to evaluate the functional activity of commercialized probiotics. In particular, the barrier effect of the samples will be investigated testing their antimicrobial activity against the principal pathogens of the gastrointestinal tract (Escherichia coli ETEC H10407, Salmonella choleraesuis serovar typhimurium, Yersenia enterocolitica).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
