We have previously shown the ability of transamidated gluten (spf) to modulate in vitro the expression of both innate and adaptive immunity markers triggered by wheat gliadin in HLA-DQ8 transgenic mice (DQ8 mice). Herein, we evaluated the effects of spf in vivo on the mucosal immune response to native gliadin in DQ8 mice.

Transamidated gluten interferes with the systemic and intestinal immune responses to native gliadin in DQ8 transgenic mice

Lucia Treppiccione
Primo
Writing – Original Draft Preparation
;
Francesco Maurano;Diomira Luongo;Mauro Rossi
2024

Abstract

We have previously shown the ability of transamidated gluten (spf) to modulate in vitro the expression of both innate and adaptive immunity markers triggered by wheat gliadin in HLA-DQ8 transgenic mice (DQ8 mice). Herein, we evaluated the effects of spf in vivo on the mucosal immune response to native gliadin in DQ8 mice.
2024
Istituto di Scienze dell'Alimentazione - ISA
celiac disease, transamidation, gluten
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/511357
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