We have previously shown the ability of transamidated gluten (spf) to modulate in vitro the expression of both innate and adaptive immunity markers triggered by wheat gliadin in HLA-DQ8 transgenic mice (DQ8 mice). Herein, we evaluated the effects of spf in vivo on the mucosal immune response to native gliadin in DQ8 mice.
The immunomodulatory potential of transamidated gluten in a transgenic mouse model of gluten sensitivity.
Lucia TreppiccioneWriting – Original Draft Preparation
;Francesco Maurano;Diomira Luongo;Vincenzo De Sena;Mauro rossi
2024
Abstract
We have previously shown the ability of transamidated gluten (spf) to modulate in vitro the expression of both innate and adaptive immunity markers triggered by wheat gliadin in HLA-DQ8 transgenic mice (DQ8 mice). Herein, we evaluated the effects of spf in vivo on the mucosal immune response to native gliadin in DQ8 mice.File in questo prodotto:
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