MAMMANO, FABIO
MAMMANO, FABIO
Istituto di Endocrinologia e Oncologia Sperimentale ''G. Salvatore'' - IEOS
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model
2024 Tettey-Matey, Abraham; Donati, Viola; Cimmino, Chiara; DI PIETRO, Chiara; Buratto, Damiano; Panarelli, Mariateresa; Reale, Alberto; Calistri, Arianna; Vittoria Fornaini, Maria; Zhou, Ruhong; Yang, Guang; Zonta, Francesco; Marazziti, Daniela; Mammano, Fabio
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice
2023 Peres, C; Sellitto, C; Nardin, C; Putti, S; Orsini, T; Di Pietro, C; Marazziti, D; Vitiello, A; Calistri, A; Rigamonti, M; Scavizzi, F; Raspa, M; Zonta, F; Yang, G; White, Tw; Mammano, F
A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels
2022 Nardin, Chiara; Tetteymatey, Abraham; Donati, Viola; Marazziti, Daniela; DI PIETRO, Chiara; Peres, Chiara; Raspa, Marcello; Zonta, Francesco; Yang, Guang; Gorelik, Maryna; Singh, Serena; Cardarelli, Lia; Sidhu Sachdev, S; Mammano, Fabio
Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling
2022 Donati, Viola; Peres, Chiara; Nardin, Chiara; Scavizzi, Ferdinando; Raspa, Marcello; Ciubotaru, Catalin D; Bortolozzi, Mario; Pedersen, Morten Gram; Mammano, Fabio
Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy
2022 Peres, Chiara; Nardin, Chiara; Yang, Guang; Mammano, Fabio
Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release
2022 Chen, Junmin; Chen, Penghui; He, Baihui; Gong, Tianyu; Li, Yue; Zhang, Jifang; Lv, Jingrong; Mammano, Fabio; Hou, Shule; Yang, Jun
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy
2022 Spielmann, Nadine; Miller, Gregor; Oprea, Tudor I.; Hsu, Chih-Wei; Fobo, Gisela; Frishman, Goar; Montrone, Corinna; Haseli Mashhadi, Hamed; Mason, Jeremy; Munoz Fuentes, Violeta; Leuchtenberger, Stefanie; Ruepp, Andreas; Wagner, Matias; Westphal, Dominik S.; Wolf, Cordula; Görlach, Agnes; Sanz-Moreno, Adrián; Cho, Yi-Li; Teperino, Raffaele; Brandmaier, Stefan; Sharma, Sapna; Galter, Isabella Rikarda; Östereicher, Manuela A.; Zapf, Lilly; Mayer-Kuckuk, Philipp; Rozman, Jan; Teboul, Lydia; Bunton-Stasyshyn, Rosie K. A.; Cater, Heather; Stewart, Michelle; Christou, Skevoulla; Westerberg, Henrik; Willett, Amelia M.; Wotton, Janine M.; Roper, Willson B.; Christiansen, Audrey E.; Ward, Christopher S.; Heaney, Jason D.; Reynolds, Corey L.; Prochazka, Jan; Bower, Lynette; Clary, David; Selloum, Mohammed; Bou About, Ghina; Wendling, Olivia; Jacobs, Hugues; Leblanc, Sophie; Meziane, Hamid; Sorg, Tania; Audain, Enrique; Gilly, Arthur; Rayner, Nigel W.; Null, Null; Aguilar-Pimentel, Juan A.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Amarie, Oana V.; Calzada-Wack, Julia; Klein-Rodewald, Tanja; da Silva-Buttkus, Patricia; Lengger, Christoph; Stoeger, Claudia; Gerlini, Raffaele; Rathkolb, Birgit; Mayr, Daniela; Seavitt, John; Gaspero, Angelina; Green, Jennie R.; Garza, Arturo; Bohat, Ritu; Wong, Leeyean; Mcelwee, Melissa L.; Kalaga, Sowmya; Rasmussen, Tara L.; Lorenzo, Isabel; Lanza, Denise G.; Samaco, Rodney C.; Veeraragaven, Surabi; Gallegos, Juan J.; Kašpárek, Petr; Petrezsélyová, Silvia; King, Ruairidh; Johnson, Sara; Cleak, James; Szkoe-Kovacs, Zsombor; Codner, Gemma; Mackenzie, Matthew; Caulder, Adam; Kenyon, Janet; Gardiner, Wendy; Phelps, Hayley; Hancock, Rhys; Norris, Claire; Moore, Michayla A.; Seluke, Audrie M.; Urban, Rachel; Kane, Coleen; Goodwin, Leslie O.; Peterson, Kevin A.; Mckay, Matthew; Cook, Jenn J.; Lowy, Jacob P.; Mcfarland, Michael; Wood, Joshua A.; Willis, Brandon J.; Tolentino, Heather; Tolentino, Todd; Schuchbauer, Michael; Salazar, Jason; Johnson, Jennifer; Munson, Rebecca; Ayadi, Abdel; Pavlovic, Guillaume; Birling, Marie-Christine; Jacquot, Sylvie; Ali-Hadji, Dalila; Charles, Philippe; Andre, Philippe; Champy, Marie-France; Riet, Fabrice; Vukobradovic, Igor; Berberovic, Zorana; Qu, Dawei; Guo, Ruolin; D'Souza, Abigail; Huang, Ziyue; Camilleri, Susan; Ganguly, Milan; Adissu, Hibret; Eskandarian, Mohammed; Shang, Xueyuan; Duffin, Kyle; Xu, Catherine; Roberton, Kyle; Laurin, Valerie; Lan, Qing; Sleep, Gillian; Creighton, Amie; Lintott, Lauri; Gertsenstein, Marina; Pereira, Monica; Tondat, Sandra; Patel, Amit; Cruz, Maribelle; Bezginov, Alex; Miller, David; Hy, Wang; Yoshiki, Atsushi; Tanaka, Nobuhiko; Tamura, Masaru; Liu, Zhiwei; Ermakova, Olga; Ferrara, Anna; Fruscoloni, Paolo; Seisenberger, Claudia; Bürger, Antje; Giesert, Florian; Null, Null; Ambrose, J. C.; Arumu gam, P.; Bevers, R.; Bleda, M.; Boardman-Pretty, F.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Fowler, T.; Giess, A.; Hamblin, A.; Henderson, S.; Hubbard, T. J. P.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Kousathanas, A.; Lahnstein, L.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mcentagart, M.; Minneci, F.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; O‘donovan, P.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Pereira, M. B.; Pullinger, J.; Rahim, T.; Rendon, A.; Rogers, T.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, S. C.; Sosinsky, A.; Stuckey, A.; Tanguy, M.; Taylor-Tavares, A. L.; Thomas, E. R. A.; Thompson, S. R.; Tucci, A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Hitz, Marc-Phillip; Zeggini, Eleftheria; Wolf, Eckhard; Sedlacek, Radislav; Murray, Steven A.; Svenson, Karen L.; Braun, Robert E.; White, Jaqueline K.; Kelsey, Lois; Gao, Xiang; Shiroishi, Toshihiko; Xu, Ying; Seong, Je Kyung; Mammano, Fabio; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Meehan, Terrence F.; Parkinson, Helen; Smedley, Damian; Mallon, Ann-Marie; Wells, Sara E.; Grallert, Harald; Wurst, Wolfgang; Marschall, Susan; Fuchs, Helmut; Brown, Steve D. M.; Flenniken, Ann M.; Nutter, Lauryl M. J.; Mckerlie, Colin; Herault, Yann; Lloyd, K. C. Kent; Dickinson, Mary E.; Gailus-Durner, Valerie; Hrabe de Angelis, Martin
Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent Ca2+ Signaling in Kölliker's Organ
2022 Sun, Lianhua; Gao, Dekun; Chen, Junmin; Hou, Shule; Li, Yue; Huang, Yuyu; Mammano, Fabio; Chen, Jianyong; Yang, Jun
Connexin hemichannel activation by s-nitrosoglutathione synergizes strongly with photodynamic therapy potentiating anti-tumor bystander killing
2021 Nardin, C; Peres, C; Putti, S; Orsini, T; Colussi, C; Mazzarda, F; Raspa, M; Scavizzi, F; Salvatore, Am; Chiani, F; Tetteymatey, A; Kuang, Y; Yang, G; Retamal, Ma; Mammano, F
CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neurons degeneration in vitro and improves neuromuscular function in SOD1G93A mice
2021 LA COGNATA, Valentina; Golini, Elisabetta; Iemmolo, Rosario; Balletta, Sara; Morello, Giovanna; De Rosa, Carla; Villari, Ambra; Marinelli, Sara; Vacca, Valentina; Bonaventura, Gabriele; Dell'Albani, Paola; Aronica, Eleonora; Mammano, Fabio; Mandillo, Silvia; Cavallaro, Sebastiano
Harnessing the therapeutic potential of antibodies targeting connexin hemichannels
2021 Buratto, Damiano; Donati, Viola; Zonta, Francesco; Mammano, Fabio
miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis
2021 Gentile, Giulia; Paciello, Fabiola; Zorzi, Veronica; Spampinato, ANTONIO GIANMARIA; Guarnaccia, Maria; Crispino, Giulia; Tetteymatey, Abraham; Scavizzi, Ferdinando; Raspa, Marcello; Rita Fetoni, Anna; Cavallaro, Sebastiano; Mammano, Fabio
Single-Cell RNA Sequencing Analysis Reveals Greater Epithelial Ridge Cells Degeneration During Postnatal Development of Cochlea in Rats
2021 Chen, Jianyong; Gao, Dekun; Chen, Junmin; Hou, Shule; He, Baihui; Li, Yue; Li, Shuna; Zhang, Fan; Sun, Xiayu; Mammano, Fabio; Sun, Lianhua; Yang, Jun; Zheng, Guiliang
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice
2020 Kuang, Yuanyua; Zorzi, Veronica; Buratto, Damiano; Ziraldo, Gaia; Mazzarda, Flavia; Peres, Chiara; Nardin, Chiara; Salvatore, ANNA MARIA; Chiani, Francesco; Scavizzi, Ferdinando; Raspa, Marcello; Qiang, Min; Chu, Youjun; Shi, Xiaojie; Li, Yu; Liu, Lili; Shi, Yaru; Zonta, Francesco; Yang, Guang; Lerner Richard, A; Mammano, Fabio
Human and mouse essentiality screens as a resource for disease gene discovery
2020 Cacheiro, Pilar; MunozFuentes, Violeta; Murray, Stephen A.; Dickinson, Mary E.; Bucan, Maja; Nutter, Lauryl M. J.; Peterson, Kevin A.; Haselimashhadi, Hamed; Flenniken, Ann M.; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, ChihWei; Christiansen, Audrey; Lanza, Denise G.; Beaudet, Arthur L.; Heaney, Jason D.; Fuchs, Helmut; GailusDurner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova, Vendula; Lelliott, Christopher J.; WardleJones, Hannah; Wells, Sara; Teboul, Lydia; Cater, Heather; Stewart, Michelle; Hough, Tertius; Wurst, Wolfgang; Sedlacek, Radislav; Adams, David J.; Seavitt, John R.; TocchiniValentini, Glauco; Mammano, Fabio; Braun, Robert E.; McKerlie, Colin; Herault, Yann; de Angelis, Martin Hrabe; Mallon, AnnMarie; Lloyd, K. C. Kent; Brown, Steve D. M.; Parkinson, Helen; Meehan, Terrence F.; Smedley, Damian; Ambrose, J. C.; Arumugam, P.; Baple, E. L.; Bleda, M.; BoardmanPretty, F.; Boissiere, J. M.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Craig, C. E. H.; Daugherty, L. C.; de Burca, A.; Devereau, A.; Elgar, G.; Foulger, R. E.; Fowler, T.; FurioTari, P.; Hackett, J. M.; Halai, D.; Hamblin, A.; Henderson, S.; Holman, J. E.; Hubbard, T. J. P.; Ibanez, K.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Lahnstein, L.; Lawson, K.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; MaleadyCrowe, F.; Mason, J.; McDonagh, E. M.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; Odhams, C. A.; Patch, C.; PerezGil, D.; Polychronopoulos, D.; Pullinger, J.; Rahim, T.; Rendon, A.; RiesgoFerreiro, P.; Rogers, T.; Ryten, M.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, K. R.; Sosinsky, A.; Spooner, W.; Stevens, H. E.; Stuckey, A.; Sultana, R.; Thomas, E. R. A.; Thompson, S. R.; Tregidgo, C.; Tucci, A.; Walsh, E.; Watters, S. A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Zarowiecki, M.; Marschall, Susan; Lengger, Christoph; Maier, Holger; Seisenberger, Claudia; Buerger, Antje; Kuehn, Ralf; Schick, Joel; Hoerlein, Andreas; Oritz, Oskar; Giesert, Florian; Beig, Joachim; Kenyon, Janet; Codner, Gemma; Fray, Martin; Johnson, Sara J.; Cleak, James; SzokeKovacs, Zsombor; Lafont, David; Vancollie, Valerie E.; McLaren, Robbie S. B.; HughesHallett, Lena; Rowley, Christine; Sanderson, Emma; Galli, Antonella; Tuck, Elizabeth; Green, Angela; Tudor, Catherine; Siragher, Emma; Dabrowska, Monika; Mazzeo, Cecilia Icoresi; Griffiths, Mark; Gannon, David; Doe, Brendan; Cockle, Nicola; Kirton, Andrea; Bottomley, Joanna; Ingle, Catherine; Ryder, Edward; Gleeson, Diane; RamirezSolis, Ramiro; Birling, MarieChristine; Pavlovic, Guillaume; Ayadi, Abdel; Hamid, Meziane; About, Ghina Bou; Champy, MarieFrance; Jacobs, Hugues; Wendling, Olivia; Leblanc, Sophie; Vasseur, Laurent; Chesler, Elissa J.; Kumar, Vivek; White, Jacqueline K.; Svenson, Karen L.; Wiegand, JeanPaul; Anderson, Laura L.; Wilcox, Troy; Clark, James; Ryan, Jennifer; Denegre, James; Stearns, Tim; Philip, Vivek; Witmeyer, Catherine; Bates, Lindsay; Seavey, Zachary; Stanley, Pamela; Willet, Amelia; Roper, Willson; Creed, Julie; Moore, Michayla; Dorr, Alex; Fraungruber, Pamelia; Presby, Rose; Mckay, Matthew; NguyenBresinsky, Dong; Goodwin, Leslie; Urban, Rachel; Kane, Coleen
Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea
2020 Mazzarda, Flavia; D'Elia, Annunziata; Massari, Roberto; De Ninno, Adele; Bertani, Francesca Romana; Businaro, Luca; Ziraldo, Gaia; Zorzi, Veronica; Nardin, Chiara; Peres, Chiara; Chiani, Francesco; Tettey-Matey, Abraham; Raspa, Marcello; Scavizzi, Ferdinando; Soluri, Alessandro; Salvatore, Anna Maria; Yang, Jun; Mammano, Fabio
The Deep Genome Project
2020 Lloyd K, C Kent; Adams David, J; Baynam, Gareth; Beaudet Arthur, L; Bosch, Fatima; Boycott Kym, M; Braun Robert, E; Caulfield, Mark; Cohn, Ronald; Dickinson Mary, E; Dobbie Michael, S; Flenniken Ann, M; Flicek, Paul; Galande, Sanjeev; Gao, Xiang; Grobler, Anne; Heaney Jason, D; Herault, Yann; De Angelis Martin, Hrabe; Lupski James, R; Lyonnet, Stanislas; Mallon, Annmarie; Mammano, Fabio; MacRae Calum, A; Mcinnes, Roderick; Mckerlie, Colin; Meehan Terrence, F; Murray Stephen, A; Nutter Lauryl, M J; Obata, Yuichi; Parkinson, Helen; Pepper Michael, S; Sedlacek, Radislav; Seong Je, Kyung; Shiroishi, Toshihiko; Smedley, Damian; Tocchinivalentini, Glauco; Valle, David; Wang ChiKuang, Leo; Wells, Sara; White, Jacqueline; Wurst, Wolfgang; Xu, Ying; Brown Steve, D M
A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function
2019 Ziraldo, Gaia; Buratto, Damiano; Kuang, Yuanyuan; Xu, Liang; Carrer, Andrea; Nardin, Chiara; Chiani, Francesco; Salvatore, ANNA MARIA; Paludetti, Gaetano; Lerner Richard, A; Yang, Guang; Zonta, Francesco; Mammano, Fabio
Coordinated calcium signalling in cochlear sensory and non-sensory cells refines afferent innervation of outer hair cells
2019 Ceriani, Federico; Hendry, Aenea; Jeng, Jingyi; Johnson Stuart, L; Stephani, Friederike; Olt, Jennifer; Holley Matthew, C; Mammano, Fabio; Engel, Jutta; Kros Corne, J; Simmons Dwayne, D; Marcotti, Walter
Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function
2019 Moore Bret, A; Flenniken Ann, M; Clary, Dave; Moshiri Ata, S; Nutter Lauryl, M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammad; Mckerlie, Colin; Thomasy Sara, M; Lloyd K, C Kent; Murphy Christopher, J; Moshiri, Ala; Brown, Steve; Wells, Sara; Mallon, Annmarie; Beaudet Arthur, L; de Angelis Martin, Hrabe; Karp, Natasha; Braun, Bob; Herault, Yann; Gao, Xiang; Obata, Yuichi; Flicek, Paul; Meehan, Terrence; Parkinson, Helen; Smedley, Damian; Seong, J K; Tocchinivalentini, Glauco; Mammano, Fabio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model | 1-gen-2024 | Tettey-Matey, Abraham; Donati, Viola; Cimmino, Chiara; DI PIETRO, Chiara; Buratto, Damiano; Panarelli, Mariateresa; Reale, Alberto; Calistri, Arianna; Vittoria Fornaini, Maria; Zhou, Ruhong; Yang, Guang; Zonta, Francesco; Marazziti, Daniela; Mammano, Fabio | |
| Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice | 1-gen-2023 | Peres, C; Sellitto, C; Nardin, C; Putti, S; Orsini, T; Di Pietro, C; Marazziti, D; Vitiello, A; Calistri, A; Rigamonti, M; Scavizzi, F; Raspa, M; Zonta, F; Yang, G; White, Tw; Mammano, F | |
| A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels | 1-gen-2022 | Nardin, Chiara; Tetteymatey, Abraham; Donati, Viola; Marazziti, Daniela; DI PIETRO, Chiara; Peres, Chiara; Raspa, Marcello; Zonta, Francesco; Yang, Guang; Gorelik, Maryna; Singh, Serena; Cardarelli, Lia; Sidhu Sachdev, S; Mammano, Fabio | |
| Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling | 1-gen-2022 | Donati, Viola; Peres, Chiara; Nardin, Chiara; Scavizzi, Ferdinando; Raspa, Marcello; Ciubotaru, Catalin D; Bortolozzi, Mario; Pedersen, Morten Gram; Mammano, Fabio | |
| Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy | 1-gen-2022 | Peres, Chiara; Nardin, Chiara; Yang, Guang; Mammano, Fabio | |
| Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release | 1-gen-2022 | Chen, Junmin; Chen, Penghui; He, Baihui; Gong, Tianyu; Li, Yue; Zhang, Jifang; Lv, Jingrong; Mammano, Fabio; Hou, Shule; Yang, Jun | |
| Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy | 1-gen-2022 | Spielmann, Nadine; Miller, Gregor; Oprea, Tudor I.; Hsu, Chih-Wei; Fobo, Gisela; Frishman, Goar; Montrone, Corinna; Haseli Mashhadi, Hamed; Mason, Jeremy; Munoz Fuentes, Violeta; Leuchtenberger, Stefanie; Ruepp, Andreas; Wagner, Matias; Westphal, Dominik S.; Wolf, Cordula; Görlach, Agnes; Sanz-Moreno, Adrián; Cho, Yi-Li; Teperino, Raffaele; Brandmaier, Stefan; Sharma, Sapna; Galter, Isabella Rikarda; Östereicher, Manuela A.; Zapf, Lilly; Mayer-Kuckuk, Philipp; Rozman, Jan; Teboul, Lydia; Bunton-Stasyshyn, Rosie K. A.; Cater, Heather; Stewart, Michelle; Christou, Skevoulla; Westerberg, Henrik; Willett, Amelia M.; Wotton, Janine M.; Roper, Willson B.; Christiansen, Audrey E.; Ward, Christopher S.; Heaney, Jason D.; Reynolds, Corey L.; Prochazka, Jan; Bower, Lynette; Clary, David; Selloum, Mohammed; Bou About, Ghina; Wendling, Olivia; Jacobs, Hugues; Leblanc, Sophie; Meziane, Hamid; Sorg, Tania; Audain, Enrique; Gilly, Arthur; Rayner, Nigel W.; Null, Null; Aguilar-Pimentel, Juan A.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Amarie, Oana V.; Calzada-Wack, Julia; Klein-Rodewald, Tanja; da Silva-Buttkus, Patricia; Lengger, Christoph; Stoeger, Claudia; Gerlini, Raffaele; Rathkolb, Birgit; Mayr, Daniela; Seavitt, John; Gaspero, Angelina; Green, Jennie R.; Garza, Arturo; Bohat, Ritu; Wong, Leeyean; Mcelwee, Melissa L.; Kalaga, Sowmya; Rasmussen, Tara L.; Lorenzo, Isabel; Lanza, Denise G.; Samaco, Rodney C.; Veeraragaven, Surabi; Gallegos, Juan J.; Kašpárek, Petr; Petrezsélyová, Silvia; King, Ruairidh; Johnson, Sara; Cleak, James; Szkoe-Kovacs, Zsombor; Codner, Gemma; Mackenzie, Matthew; Caulder, Adam; Kenyon, Janet; Gardiner, Wendy; Phelps, Hayley; Hancock, Rhys; Norris, Claire; Moore, Michayla A.; Seluke, Audrie M.; Urban, Rachel; Kane, Coleen; Goodwin, Leslie O.; Peterson, Kevin A.; Mckay, Matthew; Cook, Jenn J.; Lowy, Jacob P.; Mcfarland, Michael; Wood, Joshua A.; Willis, Brandon J.; Tolentino, Heather; Tolentino, Todd; Schuchbauer, Michael; Salazar, Jason; Johnson, Jennifer; Munson, Rebecca; Ayadi, Abdel; Pavlovic, Guillaume; Birling, Marie-Christine; Jacquot, Sylvie; Ali-Hadji, Dalila; Charles, Philippe; Andre, Philippe; Champy, Marie-France; Riet, Fabrice; Vukobradovic, Igor; Berberovic, Zorana; Qu, Dawei; Guo, Ruolin; D'Souza, Abigail; Huang, Ziyue; Camilleri, Susan; Ganguly, Milan; Adissu, Hibret; Eskandarian, Mohammed; Shang, Xueyuan; Duffin, Kyle; Xu, Catherine; Roberton, Kyle; Laurin, Valerie; Lan, Qing; Sleep, Gillian; Creighton, Amie; Lintott, Lauri; Gertsenstein, Marina; Pereira, Monica; Tondat, Sandra; Patel, Amit; Cruz, Maribelle; Bezginov, Alex; Miller, David; Hy, Wang; Yoshiki, Atsushi; Tanaka, Nobuhiko; Tamura, Masaru; Liu, Zhiwei; Ermakova, Olga; Ferrara, Anna; Fruscoloni, Paolo; Seisenberger, Claudia; Bürger, Antje; Giesert, Florian; Null, Null; Ambrose, J. C.; Arumu gam, P.; Bevers, R.; Bleda, M.; Boardman-Pretty, F.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Fowler, T.; Giess, A.; Hamblin, A.; Henderson, S.; Hubbard, T. J. P.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Kousathanas, A.; Lahnstein, L.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mcentagart, M.; Minneci, F.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; O‘donovan, P.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Pereira, M. B.; Pullinger, J.; Rahim, T.; Rendon, A.; Rogers, T.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, S. C.; Sosinsky, A.; Stuckey, A.; Tanguy, M.; Taylor-Tavares, A. L.; Thomas, E. R. A.; Thompson, S. R.; Tucci, A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Hitz, Marc-Phillip; Zeggini, Eleftheria; Wolf, Eckhard; Sedlacek, Radislav; Murray, Steven A.; Svenson, Karen L.; Braun, Robert E.; White, Jaqueline K.; Kelsey, Lois; Gao, Xiang; Shiroishi, Toshihiko; Xu, Ying; Seong, Je Kyung; Mammano, Fabio; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Meehan, Terrence F.; Parkinson, Helen; Smedley, Damian; Mallon, Ann-Marie; Wells, Sara E.; Grallert, Harald; Wurst, Wolfgang; Marschall, Susan; Fuchs, Helmut; Brown, Steve D. M.; Flenniken, Ann M.; Nutter, Lauryl M. J.; Mckerlie, Colin; Herault, Yann; Lloyd, K. C. Kent; Dickinson, Mary E.; Gailus-Durner, Valerie; Hrabe de Angelis, Martin | |
| Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent Ca<sup>2+</sup> Signaling in Kölliker's Organ | 1-gen-2022 | Sun, Lianhua; Gao, Dekun; Chen, Junmin; Hou, Shule; Li, Yue; Huang, Yuyu; Mammano, Fabio; Chen, Jianyong; Yang, Jun | |
| Connexin hemichannel activation by s-nitrosoglutathione synergizes strongly with photodynamic therapy potentiating anti-tumor bystander killing | 1-gen-2021 | Nardin, C; Peres, C; Putti, S; Orsini, T; Colussi, C; Mazzarda, F; Raspa, M; Scavizzi, F; Salvatore, Am; Chiani, F; Tetteymatey, A; Kuang, Y; Yang, G; Retamal, Ma; Mammano, F | |
| CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neurons degeneration in vitro and improves neuromuscular function in SOD1G93A mice | 1-gen-2021 | LA COGNATA, Valentina; Golini, Elisabetta; Iemmolo, Rosario; Balletta, Sara; Morello, Giovanna; De Rosa, Carla; Villari, Ambra; Marinelli, Sara; Vacca, Valentina; Bonaventura, Gabriele; Dell'Albani, Paola; Aronica, Eleonora; Mammano, Fabio; Mandillo, Silvia; Cavallaro, Sebastiano | |
| Harnessing the therapeutic potential of antibodies targeting connexin hemichannels | 1-gen-2021 | Buratto, Damiano; Donati, Viola; Zonta, Francesco; Mammano, Fabio | |
| miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis | 1-gen-2021 | Gentile, Giulia; Paciello, Fabiola; Zorzi, Veronica; Spampinato, ANTONIO GIANMARIA; Guarnaccia, Maria; Crispino, Giulia; Tetteymatey, Abraham; Scavizzi, Ferdinando; Raspa, Marcello; Rita Fetoni, Anna; Cavallaro, Sebastiano; Mammano, Fabio | |
| Single-Cell RNA Sequencing Analysis Reveals Greater Epithelial Ridge Cells Degeneration During Postnatal Development of Cochlea in Rats | 1-gen-2021 | Chen, Jianyong; Gao, Dekun; Chen, Junmin; Hou, Shule; He, Baihui; Li, Yue; Li, Shuna; Zhang, Fan; Sun, Xiayu; Mammano, Fabio; Sun, Lianhua; Yang, Jun; Zheng, Guiliang | |
| A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice | 1-gen-2020 | Kuang, Yuanyua; Zorzi, Veronica; Buratto, Damiano; Ziraldo, Gaia; Mazzarda, Flavia; Peres, Chiara; Nardin, Chiara; Salvatore, ANNA MARIA; Chiani, Francesco; Scavizzi, Ferdinando; Raspa, Marcello; Qiang, Min; Chu, Youjun; Shi, Xiaojie; Li, Yu; Liu, Lili; Shi, Yaru; Zonta, Francesco; Yang, Guang; Lerner Richard, A; Mammano, Fabio | |
| Human and mouse essentiality screens as a resource for disease gene discovery | 1-gen-2020 | Cacheiro, Pilar; MunozFuentes, Violeta; Murray, Stephen A.; Dickinson, Mary E.; Bucan, Maja; Nutter, Lauryl M. J.; Peterson, Kevin A.; Haselimashhadi, Hamed; Flenniken, Ann M.; Morgan, Hugh; Westerberg, Henrik; Konopka, Tomasz; Hsu, ChihWei; Christiansen, Audrey; Lanza, Denise G.; Beaudet, Arthur L.; Heaney, Jason D.; Fuchs, Helmut; GailusDurner, Valerie; Sorg, Tania; Prochazka, Jan; Novosadova, Vendula; Lelliott, Christopher J.; WardleJones, Hannah; Wells, Sara; Teboul, Lydia; Cater, Heather; Stewart, Michelle; Hough, Tertius; Wurst, Wolfgang; Sedlacek, Radislav; Adams, David J.; Seavitt, John R.; TocchiniValentini, Glauco; Mammano, Fabio; Braun, Robert E.; McKerlie, Colin; Herault, Yann; de Angelis, Martin Hrabe; Mallon, AnnMarie; Lloyd, K. C. Kent; Brown, Steve D. M.; Parkinson, Helen; Meehan, Terrence F.; Smedley, Damian; Ambrose, J. C.; Arumugam, P.; Baple, E. L.; Bleda, M.; BoardmanPretty, F.; Boissiere, J. M.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Craig, C. E. H.; Daugherty, L. C.; de Burca, A.; Devereau, A.; Elgar, G.; Foulger, R. E.; Fowler, T.; FurioTari, P.; Hackett, J. M.; Halai, D.; Hamblin, A.; Henderson, S.; Holman, J. E.; Hubbard, T. J. P.; Ibanez, K.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Lahnstein, L.; Lawson, K.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; MaleadyCrowe, F.; Mason, J.; McDonagh, E. M.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; Odhams, C. A.; Patch, C.; PerezGil, D.; Polychronopoulos, D.; Pullinger, J.; Rahim, T.; Rendon, A.; RiesgoFerreiro, P.; Rogers, T.; Ryten, M.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, K. R.; Sosinsky, A.; Spooner, W.; Stevens, H. E.; Stuckey, A.; Sultana, R.; Thomas, E. R. A.; Thompson, S. R.; Tregidgo, C.; Tucci, A.; Walsh, E.; Watters, S. A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Zarowiecki, M.; Marschall, Susan; Lengger, Christoph; Maier, Holger; Seisenberger, Claudia; Buerger, Antje; Kuehn, Ralf; Schick, Joel; Hoerlein, Andreas; Oritz, Oskar; Giesert, Florian; Beig, Joachim; Kenyon, Janet; Codner, Gemma; Fray, Martin; Johnson, Sara J.; Cleak, James; SzokeKovacs, Zsombor; Lafont, David; Vancollie, Valerie E.; McLaren, Robbie S. B.; HughesHallett, Lena; Rowley, Christine; Sanderson, Emma; Galli, Antonella; Tuck, Elizabeth; Green, Angela; Tudor, Catherine; Siragher, Emma; Dabrowska, Monika; Mazzeo, Cecilia Icoresi; Griffiths, Mark; Gannon, David; Doe, Brendan; Cockle, Nicola; Kirton, Andrea; Bottomley, Joanna; Ingle, Catherine; Ryder, Edward; Gleeson, Diane; RamirezSolis, Ramiro; Birling, MarieChristine; Pavlovic, Guillaume; Ayadi, Abdel; Hamid, Meziane; About, Ghina Bou; Champy, MarieFrance; Jacobs, Hugues; Wendling, Olivia; Leblanc, Sophie; Vasseur, Laurent; Chesler, Elissa J.; Kumar, Vivek; White, Jacqueline K.; Svenson, Karen L.; Wiegand, JeanPaul; Anderson, Laura L.; Wilcox, Troy; Clark, James; Ryan, Jennifer; Denegre, James; Stearns, Tim; Philip, Vivek; Witmeyer, Catherine; Bates, Lindsay; Seavey, Zachary; Stanley, Pamela; Willet, Amelia; Roper, Willson; Creed, Julie; Moore, Michayla; Dorr, Alex; Fraungruber, Pamelia; Presby, Rose; Mckay, Matthew; NguyenBresinsky, Dong; Goodwin, Leslie; Urban, Rachel; Kane, Coleen | |
| Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea | 1-gen-2020 | Mazzarda, Flavia; D'Elia, Annunziata; Massari, Roberto; De Ninno, Adele; Bertani, Francesca Romana; Businaro, Luca; Ziraldo, Gaia; Zorzi, Veronica; Nardin, Chiara; Peres, Chiara; Chiani, Francesco; Tettey-Matey, Abraham; Raspa, Marcello; Scavizzi, Ferdinando; Soluri, Alessandro; Salvatore, Anna Maria; Yang, Jun; Mammano, Fabio | |
| The Deep Genome Project | 1-gen-2020 | Lloyd K, C Kent; Adams David, J; Baynam, Gareth; Beaudet Arthur, L; Bosch, Fatima; Boycott Kym, M; Braun Robert, E; Caulfield, Mark; Cohn, Ronald; Dickinson Mary, E; Dobbie Michael, S; Flenniken Ann, M; Flicek, Paul; Galande, Sanjeev; Gao, Xiang; Grobler, Anne; Heaney Jason, D; Herault, Yann; De Angelis Martin, Hrabe; Lupski James, R; Lyonnet, Stanislas; Mallon, Annmarie; Mammano, Fabio; MacRae Calum, A; Mcinnes, Roderick; Mckerlie, Colin; Meehan Terrence, F; Murray Stephen, A; Nutter Lauryl, M J; Obata, Yuichi; Parkinson, Helen; Pepper Michael, S; Sedlacek, Radislav; Seong Je, Kyung; Shiroishi, Toshihiko; Smedley, Damian; Tocchinivalentini, Glauco; Valle, David; Wang ChiKuang, Leo; Wells, Sara; White, Jacqueline; Wurst, Wolfgang; Xu, Ying; Brown Steve, D M | |
| A Human-Derived Monoclonal Antibody Targeting Extracellular Connexin Domain Selectively Modulates Hemichannel Function | 1-gen-2019 | Ziraldo, Gaia; Buratto, Damiano; Kuang, Yuanyuan; Xu, Liang; Carrer, Andrea; Nardin, Chiara; Chiani, Francesco; Salvatore, ANNA MARIA; Paludetti, Gaetano; Lerner Richard, A; Yang, Guang; Zonta, Francesco; Mammano, Fabio | |
| Coordinated calcium signalling in cochlear sensory and non-sensory cells refines afferent innervation of outer hair cells | 1-gen-2019 | Ceriani, Federico; Hendry, Aenea; Jeng, Jingyi; Johnson Stuart, L; Stephani, Friederike; Olt, Jennifer; Holley Matthew, C; Mammano, Fabio; Engel, Jutta; Kros Corne, J; Simmons Dwayne, D; Marcotti, Walter | |
| Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function | 1-gen-2019 | Moore Bret, A; Flenniken Ann, M; Clary, Dave; Moshiri Ata, S; Nutter Lauryl, M J; Berberovic, Zorana; Owen, Celeste; Newbigging, Susan; Adissu, Hibret; Eskandarian, Mohammad; Mckerlie, Colin; Thomasy Sara, M; Lloyd K, C Kent; Murphy Christopher, J; Moshiri, Ala; Brown, Steve; Wells, Sara; Mallon, Annmarie; Beaudet Arthur, L; de Angelis Martin, Hrabe; Karp, Natasha; Braun, Bob; Herault, Yann; Gao, Xiang; Obata, Yuichi; Flicek, Paul; Meehan, Terrence; Parkinson, Helen; Smedley, Damian; Seong, J K; Tocchinivalentini, Glauco; Mammano, Fabio |