CNR Institutional Research Information System

Martelli, Alberto Maria
 Distribuzione geografica
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Continente #
NA - Nord America 1.793
AS - Asia 1.696
EU - Europa 359
SA - Sud America 336
AF - Africa 27
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 1
Totale 4.219
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Nazione #
US - Stati Uniti d'America 1.710
SG - Singapore 766
CN - Cina 320
BR - Brasile 274
HK - Hong Kong 191
VN - Vietnam 165
IT - Italia 124
FR - Francia 103
KR - Corea 64
BD - Bangladesh 59
IN - India 35
CA - Canada 33
GB - Regno Unito 26
AR - Argentina 21
NL - Olanda 20
FI - Finlandia 18
ID - Indonesia 17
JP - Giappone 17
CO - Colombia 13
DE - Germania 13
IQ - Iraq 13
MX - Messico 12
MA - Marocco 11
EC - Ecuador 9
ES - Italia 8
IL - Israele 8
JM - Giamaica 7
RS - Serbia 7
SA - Arabia Saudita 7
ZA - Sudafrica 7
CR - Costa Rica 6
GT - Guatemala 6
NI - Nicaragua 6
CL - Cile 5
PE - Perù 5
PY - Paraguay 5
UA - Ucraina 5
MY - Malesia 4
SE - Svezia 4
AE - Emirati Arabi Uniti 3
AL - Albania 3
AT - Austria 3
EG - Egitto 3
JO - Giordania 3
KE - Kenya 3
LT - Lituania 3
NP - Nepal 3
PK - Pakistan 3
RU - Federazione Russa 3
SV - El Salvador 3
TR - Turchia 3
UY - Uruguay 3
DK - Danimarca 2
DZ - Algeria 2
EE - Estonia 2
HN - Honduras 2
IE - Irlanda 2
IS - Islanda 2
OM - Oman 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
UZ - Uzbekistan 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BE - Belgio 1
BG - Bulgaria 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GR - Grecia 1
HR - Croazia 1
KG - Kirghizistan 1
KY - Cayman, isole 1
KZ - Kazakistan 1
LB - Libano 1
LV - Lettonia 1
MM - Myanmar 1
MQ - Martinica 1
NZ - Nuova Zelanda 1
PA - Panama 1
PH - Filippine 1
PL - Polonia 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
VE - Venezuela 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 4.213
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Città #
Santa Clara 563
Singapore 427
Hong Kong 190
Ashburn 153
Hefei 136
San Jose 131
Council Bluffs 97
Lauterbourg 91
Seoul 63
Ho Chi Minh City 57
Hanoi 40
Beijing 38
Buffalo 35
Los Angeles 33
Princeton 33
New York 31
Abbeville 28
Dallas 18
Helsinki 17
Chicago 16
Orem 15
Toronto 15
Atlanta 13
Chennai 11
Rome 11
São Paulo 11
Milan 10
Belo Horizonte 9
Tokyo 9
Brooklyn 8
Minamishinagawa 8
Philadelphia 8
Rio de Janeiro 8
Haiphong 7
Houston 7
Miami 7
Phoenix 7
Quito 7
Bengaluru 6
Biên Hòa 6
Da Nang 6
Managua 6
Salvador 6
The Bronx 6
Baghdad 5
Brasília 5
Catania 5
Columbus 5
Guatemala City 5
Montreal 5
San José 5
Shanghai 5
Belgrade 4
Bologna 4
Cabot 4
Denver 4
Falkenstein 4
Guarulhos 4
Jakarta 4
Johannesburg 4
Lancaster 4
Lexington 4
London 4
Manchester 4
Mexico City 4
Newark 4
Ninh Bình 4
Palermo 4
Quảng Ngãi 4
Richmond 4
San Francisco 4
Seattle 4
Stockholm 4
Thái Bình 4
Washington 4
Bogotá 3
Buenos Aires 3
Colombo 3
Detroit 3
Erbil 3
Florence 3
Hải Dương 3
Jeddah 3
Las Vegas 3
Louisville 3
McAllen 3
Montevideo 3
New Orleans 3
North Charleston 3
Orlando 3
Paris 3
Pietragalla 3
Porto Alegre 3
Queens 3
Rio Grande 3
Riyadh 3
Santo André 3
São José dos Campos 3
The Dalles 3
Verona 3
Totale 2.611
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Nome #
The potential of the nutraceutical berberine in the treatment of hepatocellular carcinoma and other liver diseases such as NAFLD and NASH 79
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance. 76
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells. 75
Subnuclear localization and differentiation-dependent increased expression of DGK-zeta in C2C12 mouse myoblasts, 75
Strutture di dati: livelli di astrazione e metodi di definizione come strumento di progetto dei programmi 73
TP53 gene status can promote sensitivity and resistance to chemotherapeutic drugs and small molecule signal transduction inhibitors 72
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. 65
Inositide signaling in the nucleus: from physiology to pathology. 64
The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. 62
The emerging multiple roles of nuclear Akt. 62
Nuclear inositides: facts and perspectives, 60
Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy 60
The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation. 58
Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia. 56
Nuclear phosphoinositides and their roles in cell biology and disease. 54
Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs. 54
Morphological and biochemical patterns in skeletal muscle apoptosis. 52
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy 52
Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia. 48
Activity of the selective I?B kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a. 47
Intranuclear 3'-phosphoinositide metabolism and Akt signaling: new mechanisms for tumorigenesis and protection against apoptosis?, 45
Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts. 45
Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells, 45
The AKT inhibitor MK-2206 is cytotoxic in hepatocarcinoma cells displaying hyperphosphorylated AKT-1 and synergizes with conventional chemotherapy 45
Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine. 45
Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment. 45
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment 45
Activity of the Novel Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 against T-Cell Acute Lymphoblastic Leukemia. 44
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy. 43
Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels. 43
Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells. 43
Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia. 43
Effects of ectopic expression of NGAL on doxorubicin sensitivity 42
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway, 42
PKC-zeta expression is lower in osteoblasts from arthritic patients: IL1-beta and TNF-alpha induce a similar decrease in non-arthritic human osteoblasts. 42
Rabphilin Localizes with the Cell Actin Cytoskeleton and Stimulates Association of Granules with F-actin Cross-linked by {alpha}-Actinin, 42
Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes, 42
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients. 41
Targeting the cancer initiating cell: The ultimate target for cancer therapy 41
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress. 40
Phosphoinositide-Phospholipase C {beta}1 Mono-Allelic Deletion Is Associated With Myelodysplastic Syndromes Evolution Into Acute Myeloid Leukemia 40
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways 40
TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-zeta-dependent cell cycle arrest. 39
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors 38
Nuclear inositides: PI-PLC signaling in cell growth, differentiation and pathology 38
Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines. 38
Exploiting p53 status to enhance effectiveness of chemotherapy by lowering associated toxicity. 38
PKR is activated in MDS patients and its subcellular localization depends on disease severity. 37
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukaemia, 37
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms. 37
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health 37
Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation, 37
Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in the resistance to therapeutic treatments of human leukemias, 37
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance. 37
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells. 36
Molecular mechanisms for pituitary thyrotroph cell growth, 36
CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis. 36
Nuclear inositide signaling in myelodysplastic syndromes. 35
The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients. 35
Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry, 35
Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy. 35
Nuclear Phospholipase C {beta}1 (PLC{beta}1) Affects CD24 Expression in Murine Erythroleukemia Cells, 35
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy. 34
The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute 34
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast 34
Synergistic induction of PI-PLCbeta1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes. 34
The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy. 33
Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia 33
Significance of subnuclear localization of key players of inositol lipid cycle, 33
Signal transduction within the nucleus: revisiting phosphoinositide inositide-specific phospholipase Cbeta1, 33
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. 33
Identification of a functional nuclear export sequence in diacylglycerol kinase-zeta 32
Significance of nuclear phospholipase C signaling through type 1 IGF receptor, 32
Intranuclear 3'-phosphoinositide metabolism and apoptosis protection in PC12 cells. 32
Nuclear inositide signaling: an appraisal of phospholipase C beta 1 behavior in myelodysplastic and leukemia cells. 32
Nuclear diacylglycerol Kinase-..... in C2C12: subnuclear localization and possible involvement in DNA replication myogenic differentiation, 32
Nuclear diacylglycerol kinases: emerging downstream regulators in cell signaling networks. 31
Nuclear diacylglycerol kinase teta activated in response to nerve growth factor stimulation of PC12 31
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway, 30
Targeting prostate cancer based on signal transduction and cell cycle pathways. 30
Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes. 30
PKR activity is required for acute leukemic cell maintenance and growth: A role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation. 30
The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin signaling network and the control of normal myelopoiesis. 30
Synergistic proapoptotic activity of recombinant trail plus the Akt inhibitor perifosine in acute myelogenous leukemia cells 29
Nuclear phosphoinositide specific phospholipase C (PI-PLC)-ss1: a central intermediary in nuclear lipid-dependent signal transduction, 29
Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts, 29
PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes. 29
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside. 29
Nuclear protein kinase C isoforms and apoptosis, 29
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS. 28
Flow cytometric detection of total and serine 473 phosphorylated Akt, 28
Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias, 28
Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation, 28
Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients, 27
Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia. 27
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells, 27
The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion. 26
Nuclear phospholipase C beta1 and cellular differentiation. 26
Nuclear expression of DG-kinase isoenzymes: possible involvement in DNA replication, 25
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells, 25
Totale 4.062
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Categoria #
all - tutte 14.270
article - articoli 13.693
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.963
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/20241 0 0 0 0 0 0 0 0 0 0 0 1
2024/20251.423 9 5 86 66 530 42 33 20 10 21 329 272
2025/20262.046 79 142 147 402 371 72 329 130 85 101 101 87
2026/2027749 110 119 285 235 0 0 0 0 0 0 0 0
Totale 4.219