LIGRESTI, ALESSIA
 Distribuzione geografica
Continente #
AS - Asia 3.645
NA - Nord America 1.353
EU - Europa 743
SA - Sud America 681
AF - Africa 50
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.478
Nazione #
SG - Singapore 1.554
US - Stati Uniti d'America 1.279
CN - Cina 867
BR - Brasile 572
HK - Hong Kong 407
VN - Vietnam 367
FR - Francia 224
IT - Italia 185
KR - Corea 154
NL - Olanda 78
IN - India 56
JP - Giappone 55
GB - Regno Unito 50
FI - Finlandia 48
DE - Germania 40
BD - Bangladesh 39
AR - Argentina 34
MX - Messico 27
CA - Canada 26
ID - Indonesia 23
EC - Ecuador 22
ES - Italia 21
IL - Israele 19
ZA - Sudafrica 19
IQ - Iraq 16
TR - Turchia 16
CO - Colombia 14
RU - Federazione Russa 14
AT - Austria 11
PK - Pakistan 11
PL - Polonia 11
SE - Svezia 9
CL - Cile 8
IE - Irlanda 8
PY - Paraguay 8
SA - Arabia Saudita 8
UA - Ucraina 8
MA - Marocco 7
PE - Perù 7
PH - Filippine 7
TN - Tunisia 7
VE - Venezuela 7
EG - Egitto 6
JO - Giordania 6
UY - Uruguay 6
AE - Emirati Arabi Uniti 4
AZ - Azerbaigian 4
CZ - Repubblica Ceca 4
DZ - Algeria 4
GR - Grecia 4
GT - Guatemala 4
JM - Giamaica 4
NP - Nepal 4
RS - Serbia 4
TT - Trinidad e Tobago 4
UZ - Uzbekistan 4
AL - Albania 3
AM - Armenia 3
AU - Australia 3
BO - Bolivia 3
DO - Repubblica Dominicana 3
GE - Georgia 3
KE - Kenya 3
MY - Malesia 3
PT - Portogallo 3
TH - Thailandia 3
BG - Bulgaria 2
DK - Danimarca 2
HN - Honduras 2
HR - Croazia 2
LB - Libano 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
TW - Taiwan 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BE - Belgio 1
BH - Bahrain 1
BM - Bermuda 1
BT - Bhutan 1
BY - Bielorussia 1
CH - Svizzera 1
CM - Camerun 1
ET - Etiopia 1
HU - Ungheria 1
IR - Iran 1
KH - Cambogia 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
NG - Nigeria 1
PR - Porto Rico 1
PS - Palestinian Territory 1
RW - Ruanda 1
SV - El Salvador 1
TM - Turkmenistan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 6.478
Città #
Singapore 932
Hong Kong 400
Hefei 387
Santa Clara 360
San Jose 199
Lauterbourg 184
Beijing 150
Seoul 149
Ho Chi Minh City 146
Ashburn 101
Hanoi 83
Dallas 70
São Paulo 49
Los Angeles 48
Naples 34
Helsinki 33
Tokyo 31
New York 29
Minamishinagawa 23
Haiphong 22
Afragola 21
Da Nang 19
Rio de Janeiro 19
Brasília 17
Council Bluffs 16
Frankfurt am Main 14
Orem 14
Bengaluru 13
Lappeenranta 13
Shenzhen 12
Atlanta 11
Houston 11
Belo Horizonte 10
Buffalo 10
Salvador 10
Curitiba 9
Montreal 9
Barcelona 8
Goiânia 8
Guangzhou 8
Uberlândia 8
Warsaw 8
Baghdad 7
Biên Hòa 7
Bắc Giang 7
Casandrino 7
Cavallino 7
Denver 7
Elk Grove Village 7
Falkenstein 7
Fortaleza 7
Guayaquil 7
Jakarta 7
Johannesburg 7
Rome 7
Thái Bình 7
Asunción 6
Bari 6
Brooklyn 6
Campinas 6
Dhaka 6
Dublin 6
London 6
Mexico City 6
Milan 6
Mumbai 6
Osasco 6
Phoenix 6
Porto Alegre 6
Quito 6
Stockholm 6
Amman 5
Guarulhos 5
Kolkata 5
Montevideo 5
Ninh Bình 5
Nuremberg 5
Sorocaba 5
Algiers 4
Amsterdam 4
Bauru 4
Castelraimondo 4
Changchun 4
Charlotte 4
Florence 4
Franca 4
João Pessoa 4
Juiz de Fora 4
Kingston 4
Lima 4
Miami 4
Montes Claros 4
Nha Trang 4
Paris 4
Phủ Lý 4
Ponta Grossa 4
Recife 4
Ribeirão Preto 4
Rio Grande 4
Santo André 4
Totale 4.009
Nome #
INSIEME NEL REALE E NEL VIRTUALE PER LA CHIMICA SOSTENIBILE 95
Iron supplementation enhances RSL3-induced ferroptosis to treat naïve and prevent castration-resistant prostate cancer 84
PNRR PE13 INF-ACT: Development of Immunomodulatory and Antiviral Lead Compounds 82
Interactions of non-THC phytocannabinoids and Cannabis extracts with TRP channels and endocannabinoid metabolic enzymes 74
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer 72
Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity 70
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists. 69
Biosynthesis of the novel endogenous 15-lipoxygenase metabolites N-13-hydroxy-octodecadienoyl-ethanolamine and 13-hydroxy-octodecadienoyl-glycerol by human neutrophils and Eosinophils 69
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 67
Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity 67
Altered endocannabinoid signalling after a high-fat diet in Apoe (-/-) mice:relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance 66
DeLA-DrugSelf: Empowering Multi-Objective De Novo Design through SELFIES Molecular Representation 66
Endocannabinoid chemical biology: a tool for the development of novel therapies 65
Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle. 65
COMPARATIVE ANALYSIS OF ENDOCANNABINOID SYSTEM GENE EXPRESSION ON METASTATIC VS PRIMITIVE MELANOMA CELL LINES. 65
Modulation of endocannabinoid tone in osteoblastic differentiation of mc3t3-e1 cells and in mouse bone tissue over time 63
Modeling Acquired Resistance to the Second-Generation Androgen Receptor Antagonist Enzalutamide in the TRAMP Model of Prostate Cancer 62
Sesquiterpene lactones with the 12,8-guaianolide skeleton from algerian Centaurea omphalotricha 61
Prostamide F2a receptor antagonists with inhibitory activity at FAAH: a way to prevent the confounding effects of pro-inflammatory mediators formed following selective FAAH inhibition? 60
Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs 59
Nanoparticle-mediated cellular uptake-controlled release as a tool to study anandamide membrane transport 58
Effect of phytocannabinoids on androgen deprivation therapy in a high-fat diet-exacerbated prostate cancer 58
Potential use of cannabimimetics in the treatment of cancer 56
N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R) 56
Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase. 54
Novel Dual-Acting Hybrids Targeting Type-2 Cannabinoid Receptors and Cholinesterase Activity Show Neuroprotective Effects In Vitro and Amelioration of Cognitive Impairment In Vivo 54
Possible endocannabinoid control of colorectal cancer growth. 53
L'ICB va al campo estivo 53
Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo 53
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation 53
Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor 52
Anandamide receptors 51
Novel selective and metabolically stable inhibitors of anandamide cellular uptake 51
Indole-2-carboxamides as allosteric modulators of the cannabinoid CB1 receptor. 51
Synthesis and molecular targets of N-13-hydroxy-octadienoyl-ethanolamine, a novel endogenous bioactive 15-lipoxygenase-derived metabolite of N-linoleoyl-ethanolamine found in the skin and saliva 50
Development of N-(1-Adamantyl)benzamides as Novel Anti-Inflammatory Multitarget Agents Acting as Dual Modulators of the Cannabinoid CB2 Receptor and Fatty Acid Amide Hydrolase 50
Profiling Allosteric Modulators of CB1R with an Allosteric Fluoroprobe 50
Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach 48
Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization 48
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor 47
"Attività laboratoriale "La Chimica in cucina" nell'ambito del Progetto "I Percorsi della Ricerca del MoSeF" - Festival Scientifico: "Fattorie Didattiche Aperte", XII ed., Ist. Zooprofilattico Sperimentale del Mezzogiorno, Portici (NA), 12-13 maggio 2018" 46
Synthesis of the Major Mammalian Metabolites of THCV 46
Alternanza Scuola Lavoro Liceo Scientifico Colombo-Marigliano (Na), AS 2017/18 46
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation. 45
FGFR blockade by pemigatinib treats naïve and castration resistant prostate cancer 45
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone 44
Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors. 44
N-adamantyl-anthranil amide derivatives: New selective ligands for the cannabinoid receptor subtype 2 (CB2R) 44
Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism 43
Actions and Regulation of Ionotropic Cannabinoid Receptors. 42
Attività laboratoriale "Sua maestà la catalisi: dai semplici reattori ai sistemi viventi" nell'ambito del Progetto "RigenerAzioni: Percorsi di rigenerazione per l'economia circolare, i beni culturali e la salute" - Festival scientifico "Futuro Remoto" XXXII - Città della Scienza, Napoli, 5-8 novembre 2018 42
New Coumarin derivatives as cholinergic and cannabinoid system modulators 42
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists 42
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease 42
Polyphenolic Profiling, Quantitative Assessment and Biological Activities of Tunisian Native Mentha rotundifolia (L.) Huds. 40
In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake 39
L'ICB va a scuola 39
ICB and AutismAidOnlus 2017/18 39
Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: Modulation at the N-portion and distal phenyl ring 38
Human eosinophils and neutrophils biosynthesize novel 15-lipoxygenase metabolites from 1-linoleoyl-glycerol and N-linoleoyl-ethanolamine 38
incontro con studenti Liceo Villari presso ICB Pozzuoli, 26ii16 38
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. 37
CANNABINOIDS AS METABOLIC REPROGRAMING AGENTS IN PROSTATE CANCER CELLS 37
Anti-cancer effects of cannabidiol in human breast carcinoma: cellular and molecular mechanisms of action and inhibition of metastatic spreading 36
A structure activity relationship study on N-arachidonoyl-aminoacids as possible endogenous inhibitors of fatty acid amide hydrolase 36
An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. 36
Further evidence for the existence of a specific process for the membrane transport of anandamide. 35
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress 35
LIVER AND ADIPOSE TISSUE ENDOCANNABINOID TONE IN DIET-INDUCEDOBESITY IS DEPENDENT ON APOLIPOPROTEIN E EXPRESSION ANDASSOCIATED WITH HEPATIC STEATOSIS AND INSULIN RESISTANCE 35
FAAH-Catalyzed C-C Bond Cleavage of a New Multitarget Analgesic Drug 35
Potential use of cannabimimetics in the treatment of cancer 34
From endocannabinoid profiling to 'endocannabinoid therapeutics' 34
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. 34
Synthesis, conformational analysis and CB(1) binding affinity of hairpin-like anandamide pseudopeptide mimetics 33
Anti-inflammatory actions of palmitoylethanolamide in an in vitro model of neurogenic inflammation 33
Tonic control of tumoral growth by endocannabinoids. 32
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides. 31
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma 31
Chemical characterisation of oxidative degradation products of D9-THC. 31
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms 31
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 31
Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands 31
Phytocannabinoids in the treatment of cancer 30
1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. 30
Possible endocannabinoid control of colorectal cancer growth. 30
The levels of the endocannabinoid receptor CB2 and its ligand 2-Arachidonoylglycerol are elevated in endometrial carcinoma. 30
Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists 29
Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide 29
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis 29
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. 29
Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor 29
Novel selective and metabolically stable inhibitors of anandamide cellular uptake 29
NON-PSYCHOTROPIC CANNABINOIDS SUPPRESS TUMOR GROWTH BY ACTING ON METABOLIC REPROGRAMMING AND ONCOGENIC PATHWAYS IN HORMONE REFRACTORY PROSTATE CANCER 29
On the toxification of anandamide by pathogenic fungi: formation of 3-hydroxy-anandamide and its activity on cannabinoid and TRPV1 receptors. 28
The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages 28
Novel selective inhibitors of anandamide re-uptake with anti-spastic activity in a mouse model of multiple sclerosis. 28
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. 28
Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism. 27
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells. 27
Anandamide receptors 27
Totale 4.535
Categoria #
all - tutte 21.853
article - articoli 16.836
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 273
Totale 38.962


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202446 0 0 0 0 0 0 0 0 6 7 25 8
2024/20252.455 4 3 258 143 336 70 19 84 111 136 674 617
2025/20264.098 219 463 476 628 741 142 630 226 220 197 156 0
Totale 6.599