MAGA, GIOVANNI
 Distribuzione geografica
Continente #
AS - Asia 4.299
NA - Nord America 1.971
EU - Europa 827
SA - Sud America 825
AF - Africa 94
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.024
Nazione #
SG - Singapore 1.907
US - Stati Uniti d'America 1.898
CN - Cina 968
BR - Brasile 681
HK - Hong Kong 476
VN - Vietnam 380
IT - Italia 376
KR - Corea 226
NL - Olanda 156
IN - India 80
GB - Regno Unito 60
DE - Germania 56
AR - Argentina 52
JP - Giappone 49
FI - Finlandia 41
IL - Israele 34
MX - Messico 33
ZA - Sudafrica 33
BD - Bangladesh 31
ID - Indonesia 21
IQ - Iraq 21
CO - Colombia 20
EC - Ecuador 20
FR - Francia 20
CA - Canada 18
RU - Federazione Russa 17
ES - Italia 16
TR - Turchia 15
VE - Venezuela 15
MA - Marocco 14
PL - Polonia 14
SA - Arabia Saudita 13
PE - Perù 11
PK - Pakistan 11
UZ - Uzbekistan 11
EG - Egitto 10
AT - Austria 9
PY - Paraguay 9
SE - Svezia 9
UA - Ucraina 9
CL - Cile 8
DZ - Algeria 8
AE - Emirati Arabi Uniti 7
KE - Kenya 7
RS - Serbia 7
TW - Taiwan 7
UY - Uruguay 7
JM - Giamaica 6
KZ - Kazakistan 5
PH - Filippine 5
TN - Tunisia 5
AL - Albania 4
AZ - Azerbaigian 4
DO - Repubblica Dominicana 4
MY - Malesia 4
AU - Australia 3
BG - Bulgaria 3
CR - Costa Rica 3
DK - Danimarca 3
KG - Kirghizistan 3
LT - Lituania 3
NG - Nigeria 3
NP - Nepal 3
TH - Thailandia 3
AM - Armenia 2
BB - Barbados 2
BE - Belgio 2
BO - Bolivia 2
BS - Bahamas 2
ET - Etiopia 2
GA - Gabon 2
GR - Grecia 2
GT - Guatemala 2
HR - Croazia 2
HU - Ungheria 2
IE - Irlanda 2
JO - Giordania 2
KW - Kuwait 2
LB - Libano 2
NZ - Nuova Zelanda 2
RO - Romania 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
BF - Burkina Faso 1
BH - Bahrain 1
BY - Bielorussia 1
CH - Svizzera 1
CW - ???statistics.table.value.countryCode.CW??? 1
CZ - Repubblica Ceca 1
EE - Estonia 1
GG - Guernsey 1
GH - Ghana 1
GN - Guinea 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
ME - Montenegro 1
MK - Macedonia 1
MM - Myanmar 1
Totale 8.010
Città #
Singapore 1.193
Santa Clara 1.064
Hefei 550
Hong Kong 474
Seoul 221
Beijing 199
Ho Chi Minh City 125
San Jose 114
Ashburn 99
Hanoi 94
Dallas 89
Los Angeles 60
Milan 58
Pavia 52
São Paulo 47
Buffalo 46
Minamishinagawa 32
Bengaluru 25
Helsinki 22
Rio de Janeiro 20
Naples 17
Belo Horizonte 16
Johannesburg 16
New York 16
Rome 16
Biên Hòa 15
Brasília 15
Da Nang 14
Frankfurt am Main 14
Haiphong 14
Lappeenranta 14
Turin 13
Dhaka 12
Porto Alegre 12
Tokyo 12
Brooklyn 11
Curitiba 11
Lima 10
Portsmouth 10
Tashkent 10
Düsseldorf 9
Guarulhos 9
Quito 9
Chennai 8
Chicago 8
Florence 8
Fortaleza 8
Goiânia 8
Lonato 8
Campinas 7
Cape Town 7
Casablanca 7
Jundiaí 7
Lauterbourg 7
Montevideo 7
Munich 7
Ninh Bình 7
Phoenix 7
Thái Bình 7
Warsaw 7
Baghdad 6
Bắc Ninh 6
Denver 6
Jeddah 6
Manaus 6
Nairobi 6
Nova Iguaçu 6
Philadelphia 6
Riyadh 6
Salvador 6
Bologna 5
Boston 5
Cairo 5
Canoas 5
Caxias do Sul 5
Cosenza 5
Falkenstein 5
Guayaquil 5
Houston 5
Hải Dương 5
Joinville 5
New Delhi 5
Palermo 5
Recife 5
Ribeirão Preto 5
Seattle 5
Vienna 5
Algiers 4
Amparo 4
Araxá 4
Atlanta 4
Baku 4
Bogotá 4
Brescia 4
Can Tho 4
Caracas 4
Carapicuíba 4
Delhi 4
Dubai 4
Greenwich 4
Totale 5.201
Nome #
AIDS: la verità negata 195
Interaction of SARS-CoV-2 Nucleocapsid Protein and Human RNA Helicases DDX1 and DDX3X Modulates Their Activities on Double-Stranded RNA 112
Batteri Spazzini e Virus che curano: come le biotecnologie riscrivono la vita 101
Human DNA Polymerase beta, but Not lambda, Can Bypass a 2-Deoxyribonolactone Lesion Together with Proliferating Cell Nuclear Antigen 77
Slow-, Tight-Binding HIV-1 Reverse Transcriptase Non-Nucleoside Inhibitors Highly Active against Drug-Resistant Mutants. 72
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors 72
Selective interaction of the human immunodeficiency virus type 1 reverse transcriptase nonnucleoside inhibitor efavirenz and its thio-substituted analog with different enzyme-substrate complexes 71
DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective 68
Unconventional Knoevenagel-type indoles: Synthesis and cell-based studies for the identification of pro-apoptotic agents 67
The power of enzyme kinetics in the drug development process 65
Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops 65
Parallel solution-phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines. 64
Arylthiopyrrole (AThP) Derivatives as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis, Structure-Activity Relationships, and Docking Studies (Part 2). 63
Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide. 62
Mechanism of interaction of novel indolylarylsulfone derivatives with K103N and Y181I mutant HIV-1 reverse transcriptase in complex with its substrates. 62
Selective targeting of the HIV-1 reverse transcriptase catalytic complex through interaction with the 61
Nevirapine resistance mutation at codon 181 of the HIV-1 reverse transcriptase confers stavudine resistance by increasing nucleotide substrate discrimination and phosphorolytic activity 60
Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. 60
Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer 58
La proteina Vif del virus HIV-1 e un fattore accessorio per la trascrittasi inversa 57
Novel pyrazolo[3,4-d]pyrimidines as dual Src-Abl inhibitors active against mutant form of Abl and the leukemia K-562 cell line 57
p15PAF binding to PCNA modulates the DNA sliding surface 57
A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping 57
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: Discovery, characterization, and crystal structure in complex with the target 56
Plant Molecular Farming as a Strategy Against COVID-19 - The Italian Perspective 56
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners. 54
Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts. 52
Ribonucleotide incorporation by human DNA polymerase eta impacts translesion synthesis and RNase H2 activity 52
A role for human dna polymerase λ in alternative lengthening of telomeres 51
Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses 50
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains. 48
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains 48
Identification and Biological Characterization of the Pyrazolo[3,4-d]pyrimidine Derivative SI388 Active as Src Inhibitor 47
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2 47
Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors. 45
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4- d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme 45
Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases 45
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment 45
Identification of a novel antiviral micro-RNA targeting the NS1 protein of the H1N1 pandemic human influenza virus and a corresponding viral escape mutation 45
Targeting ddx3x helicase activity with ba103 shows promising therapeutic effects in preclinical glioblastoma models 44
Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma 44
Intrinsic and extrinsic determinants of DNA polymerases fidelity in normal and translesion synthesis 43
DNA polymerase l interacts with PCNA in normal and translesion DNA synthesis 42
Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor 42
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 42
High flexibility of rnaseh2 catalytic activity with respect to non-canonical dna structures 42
A Motif Unique to the Human Dead-Box Protein DDX3 Is Important for Nucleic Acid Binding, ATP Hydrolysis, RNA/DNA Unwinding and HIV-1 Replication. 42
Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIII beta) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses 42
Novel Insights into the Biochemical Mechanism of CK1epsilon and its Functional Interplay with DDX3X 41
New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors 41
Synthesis and Biological Investigation of Peptidomimetic SARS-CoV-2 Main Protease (Mpro) Inhibitors Bearing Quinoline-based Heterocycles at P3. 41
Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins 41
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. 40
Indolylarylsulfones Bearing Natural and Unnatural Amino Acids. Discovery of Potent Inhibitors of HIV-1 Non-Nucleoside Wild Type and Resistant Mutant Strains Reverse Transcriptase and Coxsackie B4 Virus 40
Effect of alpha-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3H)-ones 40
Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate. 40
The 2009 Influenza Pandemic: Promising Lessons for Antiviral Therapy For Future Outbreaks. 39
Second generation PBOs show enantioselective binding to the catalytic complex of HIV-1 RT wt and drug resistant mutants. 39
DDX3X Inhibitors, an Effective Way to Overcome HIV-1 Resistance Targeting Host Proteins 39
DNA Polymerases lambda and beta: The Double-Edged Swords of DNA Repair. 38
2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies 38
Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants. 38
Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect 38
Toward the discovery of novel anti-HIV drugs. Second-generation inhibitors of the cellular ATPase DDX3 with improved anti-HIV activity: synthesis, structure-activity relationship analysis, cytotoxicity studies, and target validation. 37
CHARACTERIZATION OF MIR-1307 BY MICROARRAYS ANALYSIS 37
Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site. 36
Synthesis, biological activity, and ADME properties of novel S-DABOs/N-DABOs as HIV reverse transcriptase inhibitors 36
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections 36
DNA polymerases: discovery, characterization and functions in cellular DNA transactions 36
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants. 36
Synthesis and Biological Properties of Novel 2-Aminopyrimidin-4(3H)-ones Highly Potent against HIV-1 Mutant Strains. 36
DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection 36
Functional domains of human DNA polymerase l: a molecular anatomy approach 35
Silencing of human DNA polymerase lambda causes replication stress and is synthetically lethal with an impaired S phase checkpoint. 35
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity 35
Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity. 35
Identification of new pyrrolo[2,3-d]pyrimidines as Src tyrosine kinase inhibitors in vitro active against Glioblastoma 35
Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides. 35
Specific Targeting of Highly Conserved Residues in the HIV-1 Reverse Transcriptase Primer Grip Region. 2. Stereoselective Interaction to Overcome the Effects of Drug Resistant Mutations. 35
Mutations coferring interclass antiretroviral drug resistance and their impact on HIV-1 replicative capacity 34
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation. 34
Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors 34
Indolylarylsulfones as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: New Cyclic Substituents at Indole-2-carboxamide. 34
Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires DNA Polymerase {lambda} and Proliferating Cell Nuclear Antigen 2. 34
Synthesis and antiviral activity of novel 1,3,4-thiadiazole inhibitors of DDX3x 33
Discovery of chiral cyclopropyl dihydro-alkylthio-benzyl-oxopyrimidine (S-DABO) derivatives as potent HIV-1 reverse transcriptase inhibitors with high activity against clinically relevant mutants. 33
Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents. 32
Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication. 32
The PDZ-Ligand and Src-Homology Type 3 Domains of Epidemic Avian Influenza Virus NS1 Protein Modulate Human Src Kinase Activity during Viral Infection. 32
Substrate-Induced Stable Enzyme-Inhibitor Complex Formation Allows Tight Binding of Novel 2-Aminopyrimidin-4(3H)-ones to Drug-Resistant HIV-1 Reverse Transcriptase Mutants. 32
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1 31
LACK OF STEREOSPECIFICITY OF SUID PSEUDORABIES VIRUS THYMIDINE KINASE 31
Electron microscopic analysis reveals that replication factor C is sequestered by single-stranded DNA 31
PCNA, PARP-1 and p21: a dynamic exchange of partners. 31
Diarylpyrimidine-Dihydrobenzyloxopyrimidine Hybrids: New, Wide-Spectrum Anti-HIV-1 Agents Active at (Sub)-Nanomolar Level. 31
The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA. 31
How to win the HIV-1 drug resistance hurdle race: Running faster or jumping higher? 31
Vif is an auxiliary factor of the HIV-1 reverse transcriptase and facilitates abasic site bypass. 30
Novel host-pathogen interactions between human proteins and NS1 of epidemic avian influenza virus 30
Towards novel S-DABOC inhibitors: Synthesis, biological investigation, and molecular modeling studies. 30
Totale 4.687
Categoria #
all - tutte 26.878
article - articoli 22.329
book - libri 815
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 107
Totale 50.129


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202433 0 0 0 0 0 0 0 0 27 1 2 3
2024/20254.161 11 23 290 164 1.002 239 63 158 146 189 983 893
2025/20263.992 371 601 667 919 1.093 195 146 0 0 0 0 0
Totale 8.186