MANZONI, LEONARDO PIERPAOLO
 Distribuzione geografica
Continente #
AS - Asia 1.551
NA - Nord America 1.222
SA - Sud America 268
EU - Europa 226
AF - Africa 26
Continente sconosciuto - Info sul continente non disponibili 4
AN - Antartide 1
OC - Oceania 1
Totale 3.299
Nazione #
US - Stati Uniti d'America 1.164
SG - Singapore 617
CN - Cina 407
BR - Brasile 207
HK - Hong Kong 143
VN - Vietnam 131
KR - Corea 89
FR - Francia 84
IT - Italia 42
JP - Giappone 40
CA - Canada 32
IN - India 25
GB - Regno Unito 22
AR - Argentina 20
BD - Bangladesh 19
EC - Ecuador 13
ID - Indonesia 13
MX - Messico 12
NL - Olanda 12
CO - Colombia 10
IQ - Iraq 10
IL - Israele 9
PL - Polonia 9
DE - Germania 8
FI - Finlandia 8
TR - Turchia 8
RU - Federazione Russa 6
UA - Ucraina 6
VE - Venezuela 6
ZA - Sudafrica 6
BE - Belgio 5
ES - Italia 5
EG - Egitto 4
IE - Irlanda 4
JM - Giamaica 4
LT - Lituania 4
PE - Perù 4
SA - Arabia Saudita 4
UZ - Uzbekistan 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BN - Brunei Darussalam 3
CL - Cile 3
DZ - Algeria 3
LB - Libano 3
SE - Svezia 3
TN - Tunisia 3
UY - Uruguay 3
AT - Austria 2
CZ - Repubblica Ceca 2
DO - Repubblica Dominicana 2
GE - Georgia 2
HN - Honduras 2
KE - Kenya 2
MA - Marocco 2
MO - Macao, regione amministrativa speciale della Cina 2
MY - Malesia 2
PH - Filippine 2
PR - Porto Rico 2
PY - Paraguay 2
SC - Seychelles 2
SN - Senegal 2
SV - El Salvador 2
TW - Taiwan 2
AQ - Antartide 1
AU - Australia 1
BW - Botswana 1
CR - Costa Rica 1
EE - Estonia 1
GH - Ghana 1
HU - Ungheria 1
JO - Giordania 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MK - Macedonia 1
MV - Maldive 1
NI - Nicaragua 1
NP - Nepal 1
PK - Pakistan 1
PS - Palestinian Territory 1
QA - Qatar 1
TH - Thailandia 1
Totale 3.295
Città #
Santa Clara 520
Singapore 362
Hefei 205
Hong Kong 141
San Jose 123
Seoul 88
Lauterbourg 70
Beijing 56
Ashburn 52
Ho Chi Minh City 47
Los Angeles 47
Hanoi 31
Tokyo 26
São Paulo 15
Minamishinagawa 13
Bengaluru 9
Portland 9
Rio de Janeiro 9
Belo Horizonte 8
Dallas 8
Atlanta 7
Chicago 7
Helsinki 7
Warsaw 7
Baghdad 6
Brasília 6
Brooklyn 6
Buffalo 6
Ottawa 6
Brescia 5
Calgary 5
Frankfurt am Main 5
Guayaquil 5
Milan 5
Phoenix 5
Quito 5
Toronto 5
Charlotte 4
Denver 4
Dhaka 4
Ha Long 4
London 4
Mexico City 4
New York 4
Philadelphia 4
Rome 4
Tashkent 4
The Bronx 4
Baku 3
Bandar Seri Begawan 3
Boardman 3
Brussels 3
Buenos Aires 3
Cairo 3
Deer Park 3
Dublin 3
Guangzhou 3
Guarulhos 3
Haiphong 3
Hampton 3
Houston 3
Hải Dương 3
Indianapolis 3
Jakarta 3
Las Vegas 3
Lima 3
Memphis 3
Montevideo 3
New Delhi 3
Quận Một 3
Quận Ninh Kiều 3
Ribeirão Preto 3
Saint Paul 3
Seattle 3
Shanghai 3
St Louis 3
Stockholm 3
Amsterdam 2
Ankara 2
Araçatuba 2
Asunción 2
Barueri 2
Battle Creek 2
Birmingham 2
Bragança Paulista 2
Bắc Giang 2
Campinas 2
Can Tho 2
Cape Town 2
Cary 2
Caçapava 2
Changsha 2
Cincinnati 2
Colombo 2
Costa Mesa 2
Cotia 2
Council Bluffs 2
Cuiabá 2
Curitiba 2
Da Nang 2
Totale 2.114
Nome #
Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis 93
Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting alphavbeta3/alphavbeta5 integrins and IAP proteins 92
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2 88
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis 83
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib 79
Investigating the Interaction of Cyclic RGD Peptidomimetics with alphaVbeta6 Integrin by Biochemical and Molecular Docking Studies. 76
4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents 75
Peptidomimetic compounds and preparation of biologically active derivatives 70
Preparation of homo- and heterodimeric Smac mimetic compounds as apoptosis inducers 66
Targeting the X-Linked Inhibitor of Apoptosis Protein through 4-Substituted Azabicyclo[5.3.0]alkane Smac Mimetics. Structure, Activity, and Recognition Principles 61
Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD-paclitaxel conjugates for integrin-assisted drug delivery 60
Integrin targeted synthetic ligands for diagnostic and therapeutic applications 59
Regulation of HuR structure and function by dihydrotanshinone-I 59
A new optical imaging probe targeting alphaVbeta3 integrin in glioblastoma xenografts 58
1ST ASYMMETRIC-SYNTHESIS OF ENANTIOPURE ALPHA-SULFENYL DITHIOACETALS AND ALPHA-SULFENYL ALDEHYDES 56
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family 51
Cyclic RGD Functionalized Gold Nanoparticles for Tumor Targeting 51
Synthesis of Gd and (68) Ga Complexes in Conjugation with a Conformationally Optimized RGD Sequence as Potential MRI and PET Tumor-Imaging Probes 50
DIASTEREOSELECTIVE ADDITION OF METAL-COORDINATED AND NAKED TRI-SEC-BUTYLBOROHYDRIDES TO A NOREPHEDRINE-DERIVED 2-ACETYLOXAZOLIDINE 49
Preparation of cyclic RGD peptidomimetic-paclitaxel conjugates targeting integrin ?V?3 for use as anticancer agents 49
Synthesis of azabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 48
Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents 47
Integrin-Mediated Drug Delivery in Cancer and Cardiovascular Diseases with Peptide-Functionalized Nanoparticles 46
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 46
4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation 46
Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions 44
Synthesis of functionalized azabicycloalkane amino acids as dipeptide mimics 40
Cyclic RGD peptides containing azabicycloalkane reverse-turn mimics 40
Enhancement of the Uptake and Cytotoxic Activity of Doxorubicin in Cancer Cells by Novel cRGD-Semipeptide-Anchoring Liposomes 40
Integrin-targeted peptide- and peptidomimetic-drug conjugates for the treatment of tumors. 40
Integrin targeted cyclopeptide ligands, their preparation and use 39
New potent alpha(v)beta(3) integrin ligands based on azabicycloalkane (gamma,alpha)-dipeptide mimics 39
Biological and molecular properties of a new avb3/avb5 integrin antagonist 38
68Ga-NOTA cyclic RGD peptide for alphavbeta3 integrin imaging after myocardial infarction in small animal by CT/PET 37
Functionalised azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition 37
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy 36
Design, synthesis, conformational analysis and application of azabicycloalkane amino acids as constrained dipeptide mimics 36
Molecular targeting of imaging and drug delivery probes in Atherosclerosis 36
Click chemistry to functionalise peptidomimetics 35
Conformationally constrained dipeptides: Synthesis of bicyclic lactams by stereoselective radical cyclizations 35
Stereoselective synthesis of conformationally constrained cyclohexanediols: A set of molecular scaffolds for the synthesis of glycomimetics 34
Stereoselective synthesis of C-alpha-tetrasubstituted azabicyclo[X.3.0]alkane amino acids 34
DIASTEREOSELECTIVE ADDITION OF ORGANOMETALLIC REAGENTS TO NOR-EPHEDRINE-DERIVED 2-ACYL-N-TOSYL-OXAZOLDINES 34
Preparation of bicyclic lactams as intermediates for the synthesis of biologically active peptides 33
Synthesis of some oligopyridine-galactose conjugates and their metal complexes: a simple entry to multivalent sugar ligands 33
Cyclic RGD-Containing Functionalized Azabicycloalkane Peptides as Potent Integrin Antagonists for Tumor Targeting 33
A practical way to 2,5-disubstituted pyrrolidine derivatives 33
New SMAC mimetic compounds as apoptosis inducers 33
Stereoselective synthesis of peptidomimetic compounds as intermediates in the preparation of integrin antagonists 33
Conformational analysis of azabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 33
Froc: A New Fluorous Protective Group for Peptide and Oligosaccharide Synthesis 33
Practical stereoselective synthesis of conformationally constrained unnatural proline-based amino acids and peptidomimetics 32
Synthesis of a pseudo tetrasaccharide mimic of ganglioside GM1 32
Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids 32
Solid-phase synthesis of peptides containing reverse-turn mimetic bicyclic lactams 32
ASYMMETRIC-SYNTHESIS OF ENANTIOPURE ALPHA-SULFENYL DITHIOACETALS AND ALPHA-SULFENYL ALDEHYDES 30
Synthesis of conformationally restricted and optically pure analogues of serine-proline dipeptide via aldolic condensation 30
Synthesis of the Lewis a trisaccharide based on an anomeric silyl fuorous tag 30
Stereoselective synthesis of a functionalized 2-oxo-1-azabicyclo[5.3.0]alkane as a potential scaffold for targeted chemotherapy strategieseted chemoterapy strategies 30
Linkers nella sintesi organica in fase solida 29
Diastereoselective addition of metal-coordinated and ''naked'' nucleophilic reagents to norephedrine derived 2-acyl-N-tosyl-oxazolidines 29
SYNTHESIS OF 7,5-FUSED BICYCLIC LACTAMS BY STEREOSELECTIVE RADICAL CYCLIZATION 28
Mimics of Ganglioside GM1 as Cholera Toxin Ligands: Replacement of the GalNAC Residue 28
Preparation of peptidomimetic azabicycloalkane compounds containing the RGD sequence for use as integrin inhibitors 28
Synthesis of Lewis A and Lewis X pentasaccharides based on N-trichloroethoxycarbonyl protection 28
N-Trichloroethoxycarbonyl-glucosamine derivatives as glycosyl donors 27
Synthesis of new bicyclic lactam petptidomimetics by ring-closing metathesis reactions 27
Synthesis of N-acetylglucosamine containing Lewis A and Lewis X building blocks based on N-tetrachlorophthaloyl protection - Synthesis of Lewis X pentasaccharide 27
STRUCTURE OF N,N',N''-TRIPHENYLBIURET 27
Synthesis of spiroazabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 27
Synthesis of substituted conformationally constrained 6,5- and 7,5-fused bicyclic lactams as dipeptide mimics 27
Preparation of pyrrolo[1,2-a]pyridine and pyrrolo[1,2-a]azepine scaffolds useful for the synthesis of compounds with biological activity 27
The first example of ring-closing metathesis of dehydroamino acids: an application to the synthesis of azabicyclo[X.Y.0]alkanes 26
Synthesis of 8,5-fused bicyclic lactam by stereo- and regioselective radical cyclization 26
Rapid synthesis of oligosaccharides using an anomeric fluorous silyl protective group 26
A Potent Integrin Antagonist from a Small Library of Cyclic RGD Pentapeptide Mimics Including Benzyl-Substituted Azabicycloalkane Amino Acids 26
Stereoselective synthesis of 6,5-bicyclic reverse-turn peptidomimetics 24
Preparation of peptidomimetics as integrino inhibitors 23
CONFORMATIONALLY CONSTRAINED DIPEPTIDES - SYNTHESIS OF 7,5-FUSED AND 6,5-FUSED BICYCLIC LACTAMS BY STEREOSELECTIVE RADICAL CYCLIZATIONS 23
Potent Integrin Antagonists from a Small Library of RGD-Including Cyclic Pseudopeptides 22
Totale 3.299
Categoria #
all - tutte 11.964
article - articoli 10.334
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.298


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202413 0 0 0 0 0 0 0 0 2 0 10 1
2024/20251.325 3 4 85 46 430 113 5 63 13 11 291 261
2025/20261.607 109 175 162 260 286 41 268 61 106 34 48 57
2026/2027354 83 73 198 0 0 0 0 0 0 0 0 0
Totale 3.299