MANZONI, LEONARDO PIERPAOLO
 Distribuzione geografica
Continente #
AS - Asia 1.521
NA - Nord America 989
SA - Sud America 248
EU - Europa 206
AF - Africa 23
AN - Antartide 1
OC - Oceania 1
Totale 2.989
Nazione #
US - Stati Uniti d'America 944
SG - Singapore 614
CN - Cina 404
BR - Brasile 197
HK - Hong Kong 141
VN - Vietnam 129
KR - Corea 89
FR - Francia 83
JP - Giappone 40
IT - Italia 33
CA - Canada 25
IN - India 25
AR - Argentina 19
GB - Regno Unito 18
BD - Bangladesh 14
NL - Olanda 12
EC - Ecuador 11
IQ - Iraq 10
MX - Messico 10
IL - Israele 9
PL - Polonia 9
DE - Germania 8
FI - Finlandia 8
ID - Indonesia 8
TR - Turchia 8
CO - Colombia 6
RU - Federazione Russa 6
ZA - Sudafrica 6
ES - Italia 5
EG - Egitto 4
LT - Lituania 4
PE - Perù 4
UA - Ucraina 4
UZ - Uzbekistan 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
BE - Belgio 3
DZ - Algeria 3
IE - Irlanda 3
JM - Giamaica 3
LB - Libano 3
SA - Arabia Saudita 3
SE - Svezia 3
TN - Tunisia 3
UY - Uruguay 3
AT - Austria 2
BN - Brunei Darussalam 2
CL - Cile 2
CZ - Repubblica Ceca 2
GE - Georgia 2
HN - Honduras 2
KE - Kenya 2
PY - Paraguay 2
SN - Senegal 2
SV - El Salvador 2
TW - Taiwan 2
AQ - Antartide 1
AU - Australia 1
BW - Botswana 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GH - Ghana 1
HU - Ungheria 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LV - Lettonia 1
MA - Marocco 1
MK - Macedonia 1
MO - Macao, regione amministrativa speciale della Cina 1
MV - Maldive 1
MY - Malesia 1
NI - Nicaragua 1
NP - Nepal 1
PH - Filippine 1
PS - Palestinian Territory 1
Totale 2.989
Città #
Santa Clara 517
Singapore 359
Hefei 205
Hong Kong 140
San Jose 89
Seoul 88
Lauterbourg 70
Beijing 55
Ho Chi Minh City 46
Los Angeles 46
Ashburn 34
Hanoi 31
Tokyo 26
São Paulo 15
Minamishinagawa 13
Bengaluru 9
Portland 9
Rio de Janeiro 9
Dallas 8
Belo Horizonte 7
Helsinki 7
Warsaw 7
Atlanta 6
Baghdad 6
Buffalo 6
Ottawa 6
Brescia 5
Frankfurt am Main 5
Guayaquil 5
Brasília 4
Calgary 4
Denver 4
Ha Long 4
Mexico City 4
Milan 4
New York 4
Phoenix 4
Tashkent 4
Toronto 4
Baku 3
Boardman 3
Brussels 3
Buenos Aires 3
Cairo 3
Chicago 3
Dhaka 3
Guangzhou 3
Guarulhos 3
Haiphong 3
Hải Dương 3
Jakarta 3
Lima 3
London 3
Montevideo 3
New Delhi 3
Quito 3
Quận Một 3
Quận Ninh Kiều 3
Ribeirão Preto 3
Seattle 3
Stockholm 3
Amsterdam 2
Ankara 2
Araçatuba 2
Asunción 2
Bandar Seri Begawan 2
Barueri 2
Bragança Paulista 2
Brooklyn 2
Bắc Giang 2
Campinas 2
Can Tho 2
Cape Town 2
Cary 2
Caçapava 2
Changsha 2
Charlotte 2
Costa Mesa 2
Cotia 2
Cuiabá 2
Curitiba 2
Da Nang 2
Dakar 2
Des Moines 2
Dublin 2
El Progreso 2
Elk Grove Village 2
Garanhuns 2
Goiânia 2
Gustavo Adolfo Madero 2
Hampton 2
Ipatinga 2
Irvington 2
Itajaí 2
Las Vegas 2
Manaus 2
Miami 2
Milwaukee 2
Montreal 2
Mumbai 2
Totale 2.013
Nome #
Novel second mitochondria-derived activator of caspases (Smac) mimetic compounds sensitize human leukemic cell lines to conventional chemotherapeutic drug-induced and death receptor-mediated apoptosis 89
Synthesis and biological evaluation of dual action cyclo-RGD/SMAC mimetic conjugates targeting alphavbeta3/alphavbeta5 integrins and IAP proteins 88
Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2 82
Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib 78
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis 74
Investigating the Interaction of Cyclic RGD Peptidomimetics with alphaVbeta6 Integrin by Biochemical and Molecular Docking Studies. 73
4-Connected azabicyclo[5.3.0]decane Smac mimetics-Zn2+ chelators as dual action antitumoral agents 71
Peptidomimetic compounds and preparation of biologically active derivatives 69
Preparation of homo- and heterodimeric Smac mimetic compounds as apoptosis inducers 62
Integrin targeted synthetic ligands for diagnostic and therapeutic applications 57
Targeting the X-Linked Inhibitor of Apoptosis Protein through 4-Substituted Azabicyclo[5.3.0]alkane Smac Mimetics. Structure, Activity, and Recognition Principles 56
A new optical imaging probe targeting alphaVbeta3 integrin in glioblastoma xenografts 55
Design, synthesis and biological evaluation of novel dimeric and tetrameric cRGD-paclitaxel conjugates for integrin-assisted drug delivery 55
Regulation of HuR structure and function by dihydrotanshinone-I 53
1ST ASYMMETRIC-SYNTHESIS OF ENANTIOPURE ALPHA-SULFENYL DITHIOACETALS AND ALPHA-SULFENYL ALDEHYDES 51
Synthesis of Gd and (68) Ga Complexes in Conjugation with a Conformationally Optimized RGD Sequence as Potential MRI and PET Tumor-Imaging Probes 49
DIASTEREOSELECTIVE ADDITION OF METAL-COORDINATED AND NAKED TRI-SEC-BUTYLBOROHYDRIDES TO A NOREPHEDRINE-DERIVED 2-ACETYLOXAZOLIDINE 47
Synthesis of azabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 44
Preparation of cyclic RGD peptidomimetic-paclitaxel conjugates targeting integrin ?V?3 for use as anticancer agents 44
Structural Basis for Bivalent Smac-Mimetics Recognition in the IAP Protein Family 44
Dual action Smac mimetics-zinc chelators as pro-apoptotic antitumoral agents 44
4-Aminoproline-based arginine-glycine-aspartate integrin binders with exposed ligation points: practical in-solution synthesis, conjugation and binding affinity evaluation 43
Cyclic RGD Functionalized Gold Nanoparticles for Tumor Targeting 43
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 41
Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions 39
Enhancement of the Uptake and Cytotoxic Activity of Doxorubicin in Cancer Cells by Novel cRGD-Semipeptide-Anchoring Liposomes 39
Integrin-Mediated Drug Delivery in Cancer and Cardiovascular Diseases with Peptide-Functionalized Nanoparticles 37
Synthesis of functionalized azabicycloalkane amino acids as dipeptide mimics 36
Integrin targeted cyclopeptide ligands, their preparation and use 36
Integrin-targeted peptide- and peptidomimetic-drug conjugates for the treatment of tumors. 36
Cyclic RGD peptides containing azabicycloalkane reverse-turn mimics 35
68Ga-NOTA cyclic RGD peptide for alphavbeta3 integrin imaging after myocardial infarction in small animal by CT/PET 35
New potent alpha(v)beta(3) integrin ligands based on azabicycloalkane (gamma,alpha)-dipeptide mimics 34
Molecular targeting of imaging and drug delivery probes in Atherosclerosis 34
Conformationally constrained dipeptides: Synthesis of bicyclic lactams by stereoselective radical cyclizations 33
Functionalised azabicycloalkane amino acids by nitrone 1,3-dipolar intramolecular cycloaddition 33
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy 32
Click chemistry to functionalise peptidomimetics 31
Stereoselective synthesis of peptidomimetic compounds as intermediates in the preparation of integrin antagonists 31
Preparation of bicyclic lactams as intermediates for the synthesis of biologically active peptides 30
Synthesis of some oligopyridine-galactose conjugates and their metal complexes: a simple entry to multivalent sugar ligands 30
Stereoselective synthesis of conformationally constrained cyclohexanediols: A set of molecular scaffolds for the synthesis of glycomimetics 30
Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids 30
Froc: A New Fluorous Protective Group for Peptide and Oligosaccharide Synthesis 30
ASYMMETRIC-SYNTHESIS OF ENANTIOPURE ALPHA-SULFENYL DITHIOACETALS AND ALPHA-SULFENYL ALDEHYDES 29
Cyclic RGD-Containing Functionalized Azabicycloalkane Peptides as Potent Integrin Antagonists for Tumor Targeting 29
New SMAC mimetic compounds as apoptosis inducers 29
Biological and molecular properties of a new avb3/avb5 integrin antagonist 29
DIASTEREOSELECTIVE ADDITION OF ORGANOMETALLIC REAGENTS TO NOR-EPHEDRINE-DERIVED 2-ACYL-N-TOSYL-OXAZOLDINES 29
Linkers nella sintesi organica in fase solida 28
Practical stereoselective synthesis of conformationally constrained unnatural proline-based amino acids and peptidomimetics 28
A practical way to 2,5-disubstituted pyrrolidine derivatives 28
Design, synthesis, conformational analysis and application of azabicycloalkane amino acids as constrained dipeptide mimics 28
Stereoselective synthesis of C-alpha-tetrasubstituted azabicyclo[X.3.0]alkane amino acids 28
Synthesis of conformationally restricted and optically pure analogues of serine-proline dipeptide via aldolic condensation 27
Synthesis of the Lewis a trisaccharide based on an anomeric silyl fuorous tag 27
Stereoselective synthesis of a functionalized 2-oxo-1-azabicyclo[5.3.0]alkane as a potential scaffold for targeted chemotherapy strategieseted chemoterapy strategies 27
Solid-phase synthesis of peptides containing reverse-turn mimetic bicyclic lactams 27
Diastereoselective addition of metal-coordinated and ''naked'' nucleophilic reagents to norephedrine derived 2-acyl-N-tosyl-oxazolidines 27
SYNTHESIS OF 7,5-FUSED BICYCLIC LACTAMS BY STEREOSELECTIVE RADICAL CYCLIZATION 26
Mimics of Ganglioside GM1 as Cholera Toxin Ligands: Replacement of the GalNAC Residue 26
Synthesis of Lewis A and Lewis X pentasaccharides based on N-trichloroethoxycarbonyl protection 26
STRUCTURE OF N,N',N''-TRIPHENYLBIURET 25
Synthesis of a pseudo tetrasaccharide mimic of ganglioside GM1 25
Conformational analysis of azabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 25
The first example of ring-closing metathesis of dehydroamino acids: an application to the synthesis of azabicyclo[X.Y.0]alkanes 24
Synthesis of new bicyclic lactam petptidomimetics by ring-closing metathesis reactions 24
Synthesis of N-acetylglucosamine containing Lewis A and Lewis X building blocks based on N-tetrachlorophthaloyl protection - Synthesis of Lewis X pentasaccharide 24
Synthesis of substituted conformationally constrained 6,5- and 7,5-fused bicyclic lactams as dipeptide mimics 24
Synthesis of spiroazabicycloalkane amino acid scaffolds as reverse-turn inducer dipeptide mimics 23
Synthesis of 8,5-fused bicyclic lactam by stereo- and regioselective radical cyclization 23
Rapid synthesis of oligosaccharides using an anomeric fluorous silyl protective group 23
Preparation of peptidomimetic azabicycloalkane compounds containing the RGD sequence for use as integrin inhibitors 23
N-Trichloroethoxycarbonyl-glucosamine derivatives as glycosyl donors 22
Preparation of peptidomimetics as integrino inhibitors 22
Stereoselective synthesis of 6,5-bicyclic reverse-turn peptidomimetics 22
A Potent Integrin Antagonist from a Small Library of Cyclic RGD Pentapeptide Mimics Including Benzyl-Substituted Azabicycloalkane Amino Acids 22
Preparation of pyrrolo[1,2-a]pyridine and pyrrolo[1,2-a]azepine scaffolds useful for the synthesis of compounds with biological activity 21
Potent Integrin Antagonists from a Small Library of RGD-Including Cyclic Pseudopeptides 20
CONFORMATIONALLY CONSTRAINED DIPEPTIDES - SYNTHESIS OF 7,5-FUSED AND 6,5-FUSED BICYCLIC LACTAMS BY STEREOSELECTIVE RADICAL CYCLIZATIONS 20
Totale 2.993
Categoria #
all - tutte 10.481
article - articoli 9.043
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.524


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2023/202413 0 0 0 0 0 0 0 0 2 0 10 1
2024/20251.325 3 4 85 46 430 113 5 63 13 11 291 261
2025/20261.607 109 175 162 260 286 41 268 61 106 34 48 57
2026/202748 48 0 0 0 0 0 0 0 0 0 0 0
Totale 2.993